Erection-assisting and time-delay essential oil spray with yohimbine hydrochloride synergistic effect and preparation method thereof

Abstract

The invention relates to an erection-assisting time-delay essential oil spray with a yohimbine hydrochloride synergistic effect and a preparation method thereof; a glycerol carbonate / propylene glycol / ethanol solvent system is adopted, a transparent easily-sprayed liquid is obtained, and the problem of yohimbine high-dose dissolution troubling the industry for many years is solved. The obtained spray thoroughly avoids a plurality of harms to human bodies caused by the use of chemically synthesized anesthetic such as lidocaine benzocaine and dyclonine in classical time-delay oil, and scientifically avoids sequelae such as long-time hyperemia, edema, indistinct stabbing pain and dilatation illusion caused by biological product top-speed erection aids such as prostaglandin E1 on penis; the effects of assisting erection, delaying time, improving the quality of sexual life and avoiding sequelae are achieved; the spray prepared from a yohimbine hydrochloride / nano-coated essential oil liposome / glycerol carbonate system and an alcohol-water composition has a rapid and exact curative effect, does not have any toxic or side effect, and does not generate any adverse effect even if being used for a long time through a penis local spray transdermal technology.

Description

technical field [0001] The invention relates to a yohimbine hydrochloride synergistic essential oil spray for boosting erection and delaying time and a preparation method thereof. Background technique [0002] With the progress of the times and the acceleration of modernization, the pressure of work and life is increasing day by day. Men are facing increasingly fierce competition and suffering from diseases, especially erectile dysfunction. A related survey in Massachusetts, USA showed that 52% of men in the area were confused by such sexual health problems, and the data is astonishing. Male sexual dysfunction not only affects the physical health of male patients, but also easily leads to psychological problems such as lack of self-confidence and depression, which seriously affects the quality of life of men and the harmony and happiness of their sexual partners and families. [0003] Male sexual dysfunction includes: low libido or even no libido, inability to erect, premat...

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Problems solved by technology

[0004] The classic drugs for the treatment of male erectile dysfunction mainly include alprostadil injections, suppositories and even testosterone injections, which are inconvenient and unsafe to use

[0005] At present, the treatment of sexual dysfunction is mostly limited to oral Chinese and Western medicines and dietary therapy. Dietary therapy (including oral aphrodisiac health food with various names) is inaccurate for a long time. , the active ingredients are severely damaged, and the systemic absorption is slow, the active ingredients are rarely used locally, and the curative effect is difficult to fully exert

Although the western medicine represented by sildenafil has fast effect, long-term use has strong dependence and tolerance. What's more, the United States has reported 40 cases of blindness caused by taking Viagra, which may be related to the retrobulbar venous thrombosis caused by taking Viagra

[0006] In order to overcome the shortcomings of oral preparations and injections, the industry has introduced transdermal preparations rich in avant-garde scientific and technological achievements, such as prostaglandin E1 cream and prostaglandin E1 liposome dispersion, etc., which are applied to the penis by smearing and spraying. The goal is clear, the method of use is novel and convenient, the administration is safe, and the effect is fast. However, the swelling of the penis is obvious after long-term use, and there has been no major breakthrough in the storage stability of the preparation, which limits the large-scale popularization of this type of product

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