383 results about "Anaesthetic Agent" patented technology

The invention relates to the technical field of anesthesia effect evaluation, in particular to an anesthesia effect evaluation system based on big data, which comprises a physiological data processing module, a patient grouping and analysis module, an anesthesia risk evaluation module and an anesthesia adjustment support module. And collecting physiological indexes and types and doses of anesthetic drugs. According to the method, the real-time processing capacity of physiological data is enhanced by integrating historical health records and operation information, accurate evaluation of the instant effect of anesthetic is provided by deeply analyzing time sequence changes of heart rate and blood pressure, the response of different patient groups to the anesthetic can be recognized through grouping analysis, and the accuracy of the anesthetic is improved. Therefore, a targeted anesthesia scheme is realized, the anesthetic injection time and dosage are analyzed by using the LSTM network, the dynamic prediction of drug response is optimized, a doctor is supported to adjust the anesthetic dosage according to real-time data, the precision and safety of anesthesia management are greatly improved, and the anesthesia side effect risk is reduced.

A system and a method provide closed-loop sedation, anesthesia, or analgesia by monitoring EEG and automatically adjusting delivery of sedative, anesthetic, and / or analgesic drugs to maintain a desired or predetermined level of cortical at all echelons of care. The system and the method further monitor a subject's cortical activity to detect occurrence of burst suppression which can be indicative of unsafe depth of anesthesia or sedation. Further, the system and the method provide for alteration or cessation of administration of anesthesia or sedation based on the occurrence of burst suppression to mitigate harm to the subject.

The invention provides a compound phospholipid gel sustained release preparation and a preparation method thereof. The preparation mainly comprises a local anesthetic, a non-steroidal anti-inflammatory drug, phospholipid and water for injection. The preparation can be injected around a surgical incision or directly instilled or coated at the surgical incision to achieve the purpose of long-acting analgesia, and is used for postoperative analgesia.

Systems and methods for controlling anesthetic-mediated unconsciousness in a patient are disclosed. An electroencephalogram (EEG) of a patient under a GABAergic-anesthetic may be recorded using EEG electrodes. Unconsciousness maintained by GABAergic anesthetics, such as propofol, propanidid, and / or sevoflurane, is characterized by slow-delta oscillations (0.3-4 Hz) and alpha oscillations (8-14 Hz) that may be viewed in an electroencephalogram (EEG). An alpha modulation index and a slow modulation index may be computed to characterize the level of unconsciousness of the patient and set a desired level of unconsciousness. The system may automatically or manually adjust the infusion rate of the anesthetic to achieve the desired level of unconsciousness.

The invention relates to the technical field of anesthesia management, in particular to an anesthesia medicine excess brain function influence assessment system applying artificial intelligence, which comprises a data acquisition module, a data preprocessing module, a model training module, a real-time assessment module, a risk early warning module, a treatment suggestion module, a system interaction module and a remote monitoring module. Through the combination of a convolutional neural network and a long-short-term memory network, spatial-temporal characteristics of brain wave and functional magnetic resonance imaging data are extracted, a brain function thermodynamic diagram is generated in real time, and the influence of anesthetic drugs is analyzed; the system is combined with a reinforcement learning algorithm to dynamically adjust the anesthetic dosage, a risk early warning module dynamically adjusts a threshold value through physiological parameters and tolerance of a patient, an expert team can provide medical assistance in real time through a remote monitoring module, and brain function safety of the patient in the operation or anesthesia process is ensured; according to the invention, the safety, accuracy and individuation level of anesthesia management are effectively improved.

The invention belongs to the technical field of medicine preparation, and relates to PLGA gel used as an injectable long-acting local anesthesia medicine as well as application and a preparation method of the PLGA gel. The PLGA gel comprises the PLGA gel which is loaded with superparamagnetic Fe3O4 particles and a small molecule local anesthetic, namely, levobupivacaine (Levobupi). The PLGA hydrogel containing Fe3O4 and levobupivacaine can be used as an injectable long-acting local anesthesia medicine, and the hydrogel can be changed from liquid to solid after being injected into a living body, so that the release efficiency of the medicine is slowed down, and the local action time of the hydrogel is prolonged. In addition, the hydrogel can undergo a phase change from a solid state to a liquid state under magnetocaloric therapy (MHT), increase pore diameter, promote release of levobupivacaine, and provide enhanced pain relief in vivo. Compared with the prior art, the invention has the beneficial effects of simple synthesis and easy industrialization. The drug release rate is adjusted through the phase change of the hydrogel, super-long-acting analgesia is realized, and the analgesia time is gt; 20 days. The gel can be loaded with various local anesthesia drugs such as L-bupivacaine, and pain management can be carried out on various pain scenes clinically.

An Adaptive Neuro-Fuzzy Inference System (ANFIS) for total intravenous anesthesia management is disclosed, enabling control over administration of anesthetic agents and dynamic adjustment according to patient physiological feedback. The system processes patient data, including processed EEG signals, hemodynamic information, capnography, and pulse oximetry, to facilitate real-time anesthetic dosage adjustments.

The invention provides a concentration-adjustable anesthesia device for the anesthesiology department. The concentration-adjustable anesthesia device aims at achieving accurate adjustment and continuous medicine supply of anesthetic concentration. The device comprises a base, a support, a central controller, a double-medicine-pushing module, a medicine liquid supply system, a monitoring instrument group and an automatic cleaning system. The central controller monitors vital sign data of a patient in real time, adjusts the anesthetic concentration according to needs, and automatically gives an alarm under abnormal conditions. The double-medicine-pushing module forms a redundant medicine supply mechanism through a first medicine pipe, a second medicine pipe and an electromagnetic valve control system, automatic switching is achieved when faults occur, and it is ensured that anesthesia is not interrupted. The liquid medicine supply system adopts a disposable medicine tank, and sterile connection is achieved through a sealing ring opening and an O-shaped ring. The device is further provided with an automatic cleaning system, alcohol is sprayed through an atomizing nozzle for internal disinfection, and a fan is arranged for rapid drying. The base is provided with walking wheels, so that the equipment can move in an operating room conveniently. The device is convenient to operate and high in reliability, and anesthesia safety and equipment maintenance convenience are effectively improved.

The invention relates to the technical field of biological pharmacy, and discloses a QS-21 saponin adjuvant as well as a preparation method and application thereof, the adjuvant is a composite liposome and comprises a liposome skeleton composed of distearoyl phosphatidylcholine and cholesterol, and QS-21 saponin, monophosphoryl lipid A and a local anesthetic are jointly entrapped in the liposome skeleton. The problem that high reactogenicity and immunogenicity of potent adjuvants are difficult to consider at the same time is solved, the immunostimulation component and the pain inhibition component are jointly entrapped in the same nano-carrier, collaborative delivery in injection local is achieved, and therefore pain and swelling caused by the adjuvants are accurately inhibited. The co-entrapment structure avoids the potential inhibition effect of the free anesthetic on the immune system, the potent body fluid and cellular immune enhancement activity of the adjuvant is completely reserved, and a new technical scheme is provided for developing vaccines with high safety and strong immune efficacy.

The utility model relates to the technical field of anesthesia quantitative sprayers, and discloses a throat anesthesia quantitative sprayer which comprises a fixing cylinder, a lifting assembly is fixedly connected to the middle of the surface of the fixing cylinder, a threaded hole is formed in the surface of the fixing cylinder, and a medicine placing bottle is in threaded connection with the interior of the threaded hole. A cavity is formed in the fixing cylinder, a transmission assembly is fixedly connected to the interior of the cavity, and the surface of the transmission assembly is sleeved with a medicine containing cylinder. According to the anesthetic quantitative sprayer for anesthetizing the throat part, through the arrangement of the transmission assembly, when the anesthetic quantitative sprayer is used, a medicine containing bottle is screwed on a fixing cylinder, anesthetic in the medicine containing bottle flows into a medicine containing cylinder, an external power source is connected, a servo motor is turned on, the servo motor drives a transmission rod, the transmission rod drives a lead screw, and the lead screw rotates to enable the anesthetic to flow into a transmission pipe; the situation that medical workers manually add anesthetics is avoided, and therefore the effect of facilitating use of the medical workers is achieved.

The invention relates to the technical field of aquatic animal living body transportation, and discloses a sea urchin long-distance transportation synergistic method based on dry transportation and anhydrous volatile anesthesia, which comprises the following steps: placing sea urchin in a closed container, using a natural volatile substance as an anesthetic, loading and volatilizing through an adsorption material, and performing anhydrous anesthesia on the sea urchin; the anesthetized sea urchin is inversely placed on a fixing support with a mesh structure in a transportation container in the posture that the mouth face faces upwards and the thorns face downwards, and the sea urchin is prevented from rolling over in the transportation process through the self-locking effect of the thorns and meshes; a functional interlayer is arranged in the fixing support, and a temperature control material and a moisturizing material are placed in the functional interlayer at the same time to maintain the temperature and humidity of the transportation environment; after transportation, the sea urchins are placed in seawater containing the cactus extract for initial recovery and then transferred to flowing natural seawater to complete unified recovery, a whole-process collaborative protection chain of anhydrous anesthesia loss prevention, dry transportation steady state maintenance and rapid water phase restoration can be constructed, and the dry transportation survival rate and quality are remarkably improved.

The invention relates to the technical field of medical care information, in particular to an anesthesia preoperative medication risk assessment method, which comprises the following steps: acquiring preoperative anesthetic dose and operation time of each historical patient and different types of physiological index data of each historical patient in different operation stages; based on the preoperative anesthetic dosage and the operation time of each historical patient, the change condition of different types of physiological index data of each historical patient in different operation stages is analyzed, and risk weights generated by anesthetic medication for different types of physiological indexes are determined; and based on the risk weight, constructing an anesthetic drug risk assessment model, and performing real-time anesthetic drug risk assessment on the patient by using the constructed anesthetic drug risk assessment model. According to the method, the risk weights generated by the anesthetic drugs for different types of physiological indexes are determined in a self-adaptive manner, and the anesthetic drug risk assessment model is constructed based on the risk weights so as to perform anesthetic drug risk assessment, so that the risk assessment accuracy is effectively improved.

The invention discloses a novel compound rapid surface anesthetic and a preparation method thereof, and belongs to the field of pharmaceutical preparations. According to the anesthetic, core anesthetic components of lidocaine and tetracaine are compounded with propylene glycol-laurocapram synergistic penetration enhancer, menthol auxiliary penetration enhancer, carbomer 980 gel matrix, triethanolamine pH regulator, glycerol humectant, panthenol soothing agent, purified water and the like, a surface smearing agent is prepared through a specific process, and the anesthetic can be administered in combination with an iontophoresis technology. Compared with the existing surface anesthetic for the cosmetic surgery, the surface anesthetic disclosed by the invention solves the problems of slow effect taking and poor effect, can realize rapid penetration of local skin, has short anesthesia effect taking time, long duration and good effect, has no obvious irritation to the skin, has good product stability, can effectively reduce the drug toxicity, and has a good application prospect. The device is suitable for surface anesthesia of non-surgical medical beauty items such as skin beauty, laser treatment and water-light micro-needles.

The invention provides a concentration-adjustable anesthesia device for the anesthesiology department, and belongs to the technical field of anesthesia. Comprising an anesthesia box, and a mixing cavity is formed in the anesthesia box. A user can firstly adjust the position of a mounting plate so as to adjust and control the effective volume of a first adjusting cavity and a second adjusting cavity, then after the anesthetic in the first adjusting cavity reaches the required content, a control assembly can drive a blocking assembly to remove blocking of a first water hole, and then the anesthetic in the second adjusting cavity reaches the required content. Then the anesthetic can automatically flow into the mixing cavity through the first water hole, and similarly, after the mixing agent in the second adjusting cavity reaches the required content, the mixing agent can flow into the mixing cavity through the second water hole, so that the adding amount of the anesthetic and the adding amount of the mixing agent can be adjusted and controlled, and the accuracy of adjusting and controlling the concentration of the anesthetic is improved; and after the anesthetic is added, the anesthetic and the mixture can automatically flow into the mixing cavity to be mixed, so that the effect of improving the use effect of the anesthetic is achieved.

The present invention relates to the technical field of medical devices, and specifically to a medical anesthesia machine capable of preventing anesthetic reflux. The present invention comprises: a main body mechanism, a drug filling mechanism and a mask mechanism. The main body mechanism comprises a columnar shell and a support frame. An anti-skid column is fixedly installed on the top of the columnar shell, an anesthetic treatment medicine tube is installed on the anti-skid column, an anesthetic treatment medicine tube is fixedly connected to the inner wall of the anesthetic treatment medicine tube with an anesthetic evaporator, and a sealing plug is slidably embedded between the anesthetic treatment medicine tube and the anesthetic evaporator. During the atomization anesthesia process, the present invention can coordinate the operation of various components of the device through an automated control system according to the patient's inhalation and exhalation states, push the atomized anesthetic gas to be delivered to the mask for the patient to inhale during inhalation, stop the delivery in time and close the corresponding passage during exhalation, so that the anesthetic delivery is synchronized with the patient's breathing, which not only ensures the anesthesia effect but also greatly reduces the possibility of anesthetic reflux caused by reverse pressure difference.

The utility model relates to the technical field of medical instruments, in particular to a clinical anesthetic storage device which comprises a heat preservation mechanism and a plurality of storage mechanisms, the heat preservation mechanism comprises a heat preservation box, the storage mechanisms are symmetrically installed in the heat preservation box, and the heat preservation mechanism further comprises a partition plate and a cover plate. The partition plate is fixedly connected to the inner side wall of the heat preservation box, the cover plate is arranged at the top of the heat preservation box, and a plurality of first threaded holes are evenly formed in the upper surface of the cover plate; in the using process, when anesthetic in the heat preservation box is taken out, the cover plate does not need to be opened, the cover body is rotated, the cover body is rotated out of the first threaded hole, the cover body adsorbs the first magnetic block through the second magnetic block to drive the storage barrel to move, the storage barrel is taken out of the first threaded hole, and then the needed anesthetic can be taken out independently; when the anesthetic is taken out, a large amount of cold air is not lost, and the temperature in the heat preservation box can be kept relatively stable.

The present invention relates to a soluble microneedle for local anesthesia and a local anesthesia patch comprising same, the soluble microneedle comprising an amide-based local anesthetic, hyaluronic acid, and polyvinylpyrrolidone in a specific content ratio. The present invention uses the soluble microneedle to implement direct drug delivery by physically permeating through the stratum corneum and mucosa, and thus a precise and rapid anesthetic effect may be exhibited. Especially, the microneedle comprising a specific amount of polyvinylpyrrolidone is dissolved, and the anesthetic contained in the microneedle is rapidly delivered to nerve cells, and thus the disadvantage of a long waiting time of conventional anesthetic creams may be overcome, and thus the present invention has the advantage of being usable in various ways in dental, dermatology, and other surgical procedures requiring local anesthesia.

The invention provides an analgesic microneedle patch based on 3D printing and a preparation method and application thereof, and belongs to the technical field of biomedical materials.The preparation method of the hydrogel microneedle patch based on 3D printing comprises the following steps that 1, cold water fish skin gelatin is dissolved in DPBS, and a gelatin solution is obtained; (2) mixing methacrylic anhydride and gelatin liquid to generate polymerization reaction, so as to obtain a hydrogel material; and 3) loading an anesthetic and analgesic drug on the hydrogel material, and printing by a photocuring 3D printing method to obtain the hydrogel microneedle patch. The 3D printing technology is combined with a microneedle which is a dysmenorrhea-free skin drug delivery system, local anesthetics are loaded into the microneedle patch, on the basis of painless drug delivery, the drug delivery efficiency is improved, the drug onset time is shortened, and then the effect of effectively, rapidly and safely playing a local anesthesia role is achieved.

The invention relates to particular prodrugs and analogs of (3α,5α)-3-hydroxy-21-(1H-imidazol-1-yl)-3-methoxymethyl)-pregnan-20-one, in free or pharmaceutically acceptable salt and / or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use as sedatives, hypnotics, anxiolytics, and / or anesthetics, and methods for treatment of depression, anxiety, insomnia, epilepsy, and other central nervous system disorders, as well as to combinations with other agents.

The utility model provides an anesthetic filling device and an anesthetic vaporizer, and belongs to the technical field of medical instruments.The anesthetic filling device is installed on a bottle body containing anesthetic and comprises a connecting piece connected with a bottle opening of the bottle body; the one-way valve is at least partially arranged at the bottle opening of the bottle body and comprises a valve element, a fixing frame and an elastic piece, the valve element is movably arranged in the cavity of the connecting piece, the fixing frame is fixedly connected to the bottle opening of the bottle body, and the elastic piece is connected between the valve element and the fixing frame in an abutting mode; the valve core opens or seals the sealing port of the connecting piece under the action of external thrust and the elastic force of the elastic piece; the valve element comprises a valve element body and a plurality of elastic arms connected to the valve element body, one end of each elastic arm is fixedly connected with the valve element body, and the other end of each elastic arm is a free end. The multiple elastic arms are evenly distributed on the periphery of the valve element body in the circumferential direction, and the free ends of the elastic arms abut against the inner side wall of the connecting piece. According to the anesthetic filling device, the sealing performance of the anesthetic filling device can be improved, and anesthetic leakage during inversion is avoided.

The invention relates to the technical field of injection gel, and particularly discloses hydroxyapatite sodium hyaluronate injection gel and a preparation method thereof. The hydroxyapatite sodium hyaluronate injection gel is prepared from the following raw materials: hydroxyapatite sodium hyaluronate composite gel and a sodium hyaluronate anesthetic mixed solution, the hydroxyapatite and sodium hyaluronate composite gel is prepared from the following raw material components in parts by weight: 100 to 500 parts of hydroxyapatite microspheres, 8 to 24 parts of cross-linked sodium hyaluronate and 8 to 24 parts of collagen, the sodium hyaluronate anesthetic mixed solution is prepared from the following raw material components in parts by weight: 0.5 to 1.5 parts of sodium hyaluronate dry powder and 1 to 5 parts of anesthetic.

The invention discloses a low-stress bleeding processing method for channel catfish. The method comprises the following steps: an acid-base control step, in which the channel catfish is placed in water containing sodium citrate to control the acid-base in the body, thereby increasing the alkali reserve in the body of the fish; a combined light anesthesia step, in which the channel catfish is lightly anesthetized through the combined action of low temperature and a chemical anesthetic, so that the fish exhibits a state in which the gill cover of the fish opens and closes weakly and slowly, and the fish body rolls over and loses balance; a fish body puncture step, in which the blood circulation of the channel catfish is destroyed by a manual or mechanical method, thereby creating a bleeding wound on the fish body; a metabolic bleeding step, in which the fish body is placed in a bleeding tank that has been aerated and oxygenated in advance to saturated dissolved oxygen, for bleeding, while maintaining a certain dissolved oxygen concentration; and an ultrasonic blood purification step, in which the fish body is placed in a bleeding tank equipped with an ultrasonic device for bleeding, thereby accelerating the discharge of residual blood in the body.

The invention relates to a breathing system and a breathing method for artificial respiration of a patient. The invention further relates to a control assembly and a control method for controlling a breathing assembly belonging to a breathing system. The anesthetic meter member (38) provides an anesthetic gas mixture (Ng) having a predetermined theoretical concentration (conreq) of the anesthetic (Nm). The respirator (12) delivers a breathable gas mixture with an anesthetic gas mixture (Ng) to the patient-side coupling unit. The setpoint concentration (conreq) is specified in such a way that the setpoint concentration is at most equal to the calculated upper concentration limit (conmax). The higher the temperature in the anesthetic meter member (38), in the ventilator (12) and / or in the ambient environment, the higher the concentration upper limit (conmax). The present invention reduces the risk of anesthetic (Nm) coagulation.

A system (100) and method (1000) for managing fluid administration to a patient (120) following administration of an anaesthetic. The system (100) comprises a processor (112) configured to receive monitored patient haemoglobin data before and after the administration of the anaesthetic. The processor (112) is configured to calculate a baseline blood volume (BBV) of the patient (120). After administration of the anaesthetic, the processor (112) is configured to calculate a target blood volume (TBV), wherein the target blood volume (TBV) is calculated by comparing the monitored patient haemoglobin data before and after the administration of the anaesthetic.

The invention relates to the field of anesthetic quantification, in particular to an anesthetic quantitative conveying device of an anesthesia machine in an operating room, which comprises a table top, a bottom plate, a box body, a quantitative groove and a buffer groove, the bottom plate is fixed at the upper end of the table top, the box body is fixed at the upper end of the bottom plate, the quantitative groove is arranged on one side of the box body, and a piston I is arranged in the quantitative groove; and a lead screw is rotationally installed at the upper end of the first piston, a movable frame is rotationally installed at the end, penetrating through the upper end of the quantitative groove, of the lead screw, a mounting frame is arranged on one side of the quantitative groove, a height-adjustable lifting frame is connected to the mounting frame in an inserted mode, and a buffer groove is formed in the upper end of the lifting frame. The height of the piston can be adjusted by driving the screw rod through the motor, precise quantification is realized by combining infrared distance measurement, negative pressure is formed by utilizing the design of the piston II and the spring of the buffer groove, liquid medicine is prevented from flowing back and dripping, and the operation convenience and the medicine utilization rate are improved; the problem that an existing anesthetic quantifying device for the operating room lacks accurate quantifying and liquid leakage preventing functions is solved.

A novel active agent-eluting hemostatic agent and methods of use and manufacture thereof are presented. A polymer, such as gelatin, is used as the base for a hemostatic agent. The gelatin is crosslinked with a chemical crosslinker, such as a carbodiimide, in the presence of an active agent. The active agent may be an anesthetic or antimicrobial, such as an antibiotic. The novel process allows for the active agent to be both covalently bound to the gelatin as well as be trapped within cages in the gelatin that are formed from the crosslinking. This dual measure allows for controlled and sustained release of the active agent from the hemostatic agent to reduce surgical site infections.

The anesthesia cabin comprises a shell and a guide pipe, the guide pipe vertically penetrates into the middle of the interior of the shell, an excrement leaking net is arranged in the position, on the outer side of the middle of the guide pipe, of the interior of the shell, and a bearing frame is rotationally matched with the position, on the outer side of the guide pipe, below the excrement leaking net; a hollow base is detachably arranged on the bottom side of the shell, a volatilization frame is arranged at the position, on the inner side of the base, of the bottom of the bearing frame, and a motor for driving the bearing frame to rotate is arranged on one side in the base. The volatilization frame comprises a disc-shaped movable disc, and a universal joint hinged to the bottom side of the bearing frame is arranged in the center of the top side of the movable disc. The anesthesia cabin has the beneficial effects that the movable disc synchronously rotating along with the bearing frame is arranged on the inner side of the base of the anesthesia cabin, an anesthetic is guided to flow and volatilize through the vortex-shaped flowing groove in the upper surface of the movable disc, and meanwhile the movable disc is guided to swing and rotate through the wavy guiding groove in the rotating process of the movable disc; the volatilization speed of anesthetic on the upper surface of the movable disc is accelerated.

The topical composition is for application to a portion of skin at a locus of postsurgical pain and comprises: an amount of anti-inflammatory analgesic; an amount of muscle relaxant; an amount of neuropathic analgesic; an amount of anesthetic; and a carrier having skin penetration enhancement qualities.

The present invention belongs to the technical field of biomedicine, and particularly relates to an anesthetic preparation containing trimecaine and a preparation method thereof. The anesthetic preparation containing trimecaine comprises the following raw materials in parts by weight: 8-12 parts of trimecaine, 0.5-1 part of lindenenolide, 0.3-0.8 part of sodium phytate, 1-5 parts of schizophyllan oligosaccharide, 3-5 parts of 1,2-propanediol, 2-6 parts of sodium carboxymethylcellulose, 3-8 parts of Tween, and 60-70 parts of physiological saline. The combination of lindenenolide and trimecaine added in the anesthetic preparation of the present invention can improve the anesthetic effect and prolong the anesthetic time. Sodium phytate and schizophyllan oligosaccharide in the anesthetic preparation act synergistically to effectively improve the stability of the anesthetic preparation. Among them, due to the film-forming property of schizophyllan oligosaccharide, it can also improve the anesthetic efficacy of the anesthetic preparation to a certain extent. In addition, the anesthetic prepared by the present invention has no obvious irritation to the skin.

The invention relates to the technical field of syringes, and discloses an anesthetic syringe which comprises a needle cylinder, and the outer wall of the needle cylinder is fixedly sleeved with a limiting wing ring; the connecting mechanism is arranged on the needle cylinder, and the connecting mechanism is used for disassembling and assembling the needle cylinder; the constant-speed pushing mechanism is arranged on the connecting mechanism, and the constant-speed pushing mechanism is used for stably pushing the anesthetic; the constant-speed pushing mechanism comprises a strip-shaped frame piece, and a lead screw is rotationally connected to the inner wall of the strip-shaped frame piece. Through the cooperative design of the constant-speed pushing mechanism and the connecting mechanism, a needle cylinder loaded with anesthetics can be fixed by means of the connecting mechanism, a user can hold the needle cylinder from the grip with one hand and rotate the rotating wheel with the other hand, the pushing block can be driven to translate at a relatively constant speed by rotating the rotating wheel, and a piston is pushed at a constant speed; the stability of injection work is improved, and the discomfort of a patient in the injection process is remarkably reduced.