An industrialized method for continuously extracting high-content marigold flavonoids

A technology with high content of marigold flavonoids, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, allergic diseases, etc., can solve the problems of complex extraction operations of marigold flavonoids and low product purity, and achieve high production capacity and easy operation Simple, the effect of improving industrial efficiency

Active Publication Date: 2022-05-20
CHENGUANG BIOTECH GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the defects of complex extraction operation and low product purity of the existing marigold flavonoids

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] 1) Use a granulator to granulate the marigold flower meal, adjust the ring die compression ratio of the granulator to 1:1.8, and feed steam to granulate;

[0035] 2) For 100kg marigold granules, add 0.4m 3 98% acetone, extracted 4 times, each time for 1 hour, the temperature of the extract was about 52°C;

[0036] 3) the extract is concentrated until the volume fraction of acetone is about 10%;

[0037] 4) filter to obtain filtrate and filter cake;

[0038] 5) The filter cake is transported to a dryer for drying to obtain the product of Example 1.

Embodiment 2

[0040] Compared with Example 1, the difference is that the step 1) ring die compression ratio is 1:1.2, and other operations are the same as in Example 1 to obtain the product of Example 2.

Embodiment 3

[0042] Compared with Example 1, the difference is that the step 1) ring die compression ratio is 1:2.2, and other operations are the same as in Example 1 to obtain the product of Example 3.

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PUM

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Abstract

The invention discloses an industrial method for continuously extracting high-content marigold flavonoids, which comprises the following steps: 1) granulating marigold flower raw materials, and the ring die compression ratio of the granulator is 1:(1.2-2.2); 2) 70%-100% acetone is used as an extractant to extract the above-mentioned marigold flower particles, and filter to obtain an extract; 3) lower the volume fraction of acetone to 0-30%, filter to obtain a filter cake, and dry the filter cake to obtain a marigold Flavonoid products. The method is simple, has strong continuity and operability, high production capacity and low energy consumption, and is suitable for industrialized production.

Description

technical field [0001] The invention belongs to the technical field of natural plant extraction, and in particular relates to an industrialized method for continuously extracting high-content marigold flavonoids. Background technique [0002] Marigold (Tagetes erecta L) is an annual herbaceous plant belonging to the genus Tagetes in the Asteraceae family. It has the functions of clearing heat and detoxifying, reducing phlegm and relieving cough; it has fragrance and can be used as fragrance agent; it has been used as antibacterial, sedative and antispasmodic agent in the past. Marigold flowers mainly contain flavonoids, glycosides, amino acids, vitamins, pigments and other ingredients. Marigold flavonoids are yellow-green powder extracted from marigold flowers. Its main component is quercetin tagetin, accounting for about 80% of marigold flavonoids. It has anti-inflammatory, anti-allergic, hypotensive, anti-arrhythmic, anti- Platelet aggregation, anti-oxidation, anti-tumor...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61P29/00A61P37/08A61P9/12A61P9/06A61P7/02A61P39/06A61P35/00A61K133/00
CPCA61K36/28A61P29/00A61P37/08A61P9/12A61P9/06A61P7/02A61P39/06A61P35/00A61K2236/333
Inventor 高兰兰吴迪崔平永
Owner CHENGUANG BIOTECH GRP CO LTD
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