Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of medicine, can solve problems such as inappropriate prevention of sleep disorders, unclear ingredients, unclear action targets, etc., and achieve clear action targets and pharmacological effects, clear effective ingredients, anti-inflammatory and antioxidant properties. The effect of protecting neurons

Inactive Publication Date: 2021-07-09
SHENZHEN ELDERLY MEDICAL RES INST +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned medicines are not suitable for the prevention of sleep disorders, and have the disadvantages of unclear ingredients and unclear targets

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041]A traditional Chinese medicine composition made from the following raw materials: jujube seed 9g, nutmeg 6g, short stem five plus 6g, thistle 6g, moringa leaf 5g, coriander 5g, ebony plum 9g, lily 9g, poria cocos 9g, gardenia 6g, cinnamon 3g, licorice 3g, γ-aminobutyric acid 0.3g, chitooligosaccharide 0.5g.

[0042] The preparation method of Chinese medicine composition comprises the following steps:

[0043] Step 1: Weigh the medicinal materials or decoction pieces corresponding to the weight of the above prescription, add 10 times the weight of water to soak for 30 minutes, heat and reflux at 100 degrees Celsius for 1 hour, filter the reflux liquid with a 200-mesh filter, keep the filtrate, and add 10 times the weight of the obtained filter residue The water was heated and refluxed for 1 hour, and the reflux liquid was filtered with a 200-mesh filter, and the filtrate was retained, and the two extracts were combined, concentrated under reduced pressure to a thick extra...

Embodiment 2

[0052] The difference from Example 1 is that the dosage form of the traditional Chinese medicine composition in this example is an oral liquid preparation. The difference between the preparation method described and the preparation method in Example 1 is that after obtaining a concentrate with a density of about 1.08 under reduced pressure in step 1, refrigerate for 24 hours, centrifugally filter, then add 0.3 g of gamma-aminobutyric acid, shell Add 0.5 g of oligosaccharide, add potassium sorbate 0.2% (wt) or other bacteriostatic agents, appropriate amount of corrective agent, dissolve, stir evenly, and make liquid drinks, oral liquids, mixtures, etc.

[0053] Wherein the flavoring agent includes steviol glycoside, glycyrrhizin, honey, etc., and the bacteriostatic agent includes potassium sorbate, ethyl niplatinate, sodium benzoate, etc.

[0054] [Specification]: 10ml / bottle, 20ml / bottle, etc.; specifications can be adjusted according to production or market needs.

Embodiment 3

[0056] The difference from Example 1 is that the dosage form of the traditional Chinese medicine composition in this example is compressed candy. The difference between the specific method and Example 1 is that 0.3 g of gamma-aminobutyric acid and 0.5 g of chitosan oligosaccharide are added to the concentrate obtained in step 1, dried, pulverized, and pressed into tablets using pharmaceutically acceptable equipment and auxiliary materials. , made into tablet candies.

[0057] [Specification]: 0.5g / piece, 1g / piece, etc., the specification can be adjusted according to production or market needs.

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Abstract

The invention belongs to the field of medicine, and particularly relates to a traditional Chinese medicine composition, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 3-30 parts of semen ziziphi spinosae, 1-15 parts of semen myristicae, 3-30 parts of acanthopanax sessiliflorus, 1-15 parts of herba cepbalanoplosis segeti, 1-15 parts of horseradish tree leaves, 1-15 parts of coriander, 1-15 parts of smoked plums, 1-30 parts of lilies, 3-30 parts of poria cocos, 1-10 parts of fructus gardeniae, 1-10 parts of cortex cinnamomi, 1-6 parts of liquorice, 0.1-3 parts of gamma-aminobutyric acid and 0.1-3 parts of chitosan oligosaccharide. The composition has the beneficial effects that the composition is prepared from medicinal and edible medicinal materials, can be used as a medicated diet food therapy product for preventing the sleep disorder, has the advantages of clear components and clear action targets, and has a remarkable effect when being used as a medicine for treating the sleep disorder.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition, a preparation method and an application thereof. Background technique [0002] Sleep disorders are disorders of the human body's sleep and wake mechanism due to various reasons. The incidence of insomnia among adults in my country has reached 38.2%, and among them, the incidence of insomnia in the elderly is as high as 74.1%. Long-term sleep disturbance seriously endangers health and often leads to mental illness. [0003] At present, the main treatments for sleep disorders are western medicines, including antihistamines, sedative-hypnotic drugs, antidepressants, etc. While the treatment of western medicine improves sleep disorders, it is often accompanied by daytime sleepiness, impaired cognitive function and psychomotor function. , and serious side effects such as rebound and withdrawal symptoms. [0004] Chinese medicine treatm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61P25/20A61K31/197A61K31/722
CPCA61K31/197A61K31/722A61K36/076A61K36/185A61K36/23A61K36/254A61K36/28A61K36/484A61K36/54A61K36/725A61K36/736A61K36/744A61K36/8967A61P25/20A61K2300/00
Inventor 吴正治梁少瑜李艳吴俊洪刘洁人刘展艳
Owner SHENZHEN ELDERLY MEDICAL RES INST
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