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Transdermal patch for treating ascites due to cirrhosis and preparation method thereof

A technology of liver cirrhosis ascites and transdermal patch, applied in the direction of non-active ingredient medical preparations, medical preparations containing active ingredients, digestive system, etc., can solve skin foaming, edge leakage, increase body surface pollution Difficulty of cleaning etc.

Pending Publication Date: 2021-07-23
吴晶
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the moisture in the paste medicine is beneficial for the medicinal effect particles of the medicine to enter the human body and circulate in the blood vessels more conveniently with the movement of water molecules, however, there is evaporation of water vapor in the relatively mild airtight environment where the skin of the acupoints is located. The water vapor released can only be limited between the application and the skin at the acupoints, and the water vapor cannot be discharged to the external environment and then volatilized, which will cause skin blistering and other damage to the skin surface of the set part due to long-term soaking in a humid environment
In particular, when the patient is in any non-lying position, the moisture under the application may gather to the edge of the low level under the action of gravity and wet the edge patch or even leak from the edge position of the patch, greatly It increases the difficulty of cleaning the dirt on the patient's body surface during the external treatment process, and at the same time, the outflow of water may contain some medicinal substances, which leads to the loss of medicinal substances, and finally makes the treatment effect not up to standard

Method used

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  • Transdermal patch for treating ascites due to cirrhosis and preparation method thereof
  • Transdermal patch for treating ascites due to cirrhosis and preparation method thereof
  • Transdermal patch for treating ascites due to cirrhosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] A transdermal patch for treating liver cirrhosis ascites, comprising a patch body 2 and a patch medicament 1.

[0048] Application medicament 1 comprises the raw material of following weight fraction:

[0049] 50 parts of raw astragalus, 20 parts of morning glory, 20 parts of rhubarb, 20 parts of Gansui, 20 parts of curcuma, 20 parts of coix seed, 20 parts of Scutellaria barbata, 10 parts of peach kernel, 10 parts of safflower, and 5 parts of borneol.

[0050] The preparation method of application medicament 1 is:

[0051] The medicinal materials are mixed, and the raw astragalus, morning glory, rhubarb, kansui, curcuma, coix seed, banzhilian, peach kernel, safflower, and borneol configured in the above weight parts are screened out of impurities and mixed to obtain a mixed medicinal material.

[0052] The drug material is crushed, the above mixed drug is added to the crushing chamber of the conventional drug crushing device, and the mixed drug is crushed by the crushi...

Embodiment 2

[0057] A transdermal patch for treating liver cirrhosis ascites, comprising a patch body 2 and a patch medicament 1.

[0058] Application medicament 1 comprises the raw material of following weight fraction:

[0059] 50 parts of astragalus, 20 parts of kansui, 20 parts of curcuma, 20 parts of coix seed, 20 parts of Scutellaria barbata, 10 parts of rhubarb, 10 parts of peach kernel, 10 parts of safflower, and 5 parts of borneol.

[0060] The preparation method of application medicament 1 is:

[0061] The medicinal materials are mixed, and the raw astragalus, morning glory, rhubarb, kansui, curcuma, coix seed, banzhilian, peach kernel, safflower, and borneol configured in the above weight parts are screened out of impurities and mixed to obtain a mixed medicinal material.

[0062] The drug material is crushed, the above mixed drug is added to the crushing chamber of the conventional drug crushing device, and the mixed drug is crushed by the crushing device, so that the large pa...

Embodiment 3

[0067] The invention provides a transdermal patch for treating liver cirrhosis ascites. Such as Figure 4 As shown, the transdermal patch includes an application agent 1 for external treatment and an application body 2 capable of confining the application agent 1 on the surface of a predetermined acupoint. The applicator body 2 includes a tissue contact layer 3 , a heating component 4 , a backing layer 5 and a water-absorbing layer 6 .

[0068] The tissue contact layer 3 is used for accommodating the applicator 1 , and it can pack the boiled applicator 1 into its body. A heating component 4 can also be optionally installed on the first surface of the tissue contacting layer 3, so that the heating component 4 can adjustably heat the applied medicine 1 in the tissue contacting layer 3 for a long time according to actual needs. The heating component 4 is used to heat the application medicine 1 applied on the set acupuncture point. According to the patient's requirements for th...

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PUM

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Abstract

The invention relates to a transdermal patch for treating ascites due to cirrhosis. The transdermal patch comprises a patch medicament (1) which can be placed on the skin surface of a set acupoint for external application treatment, wherein the patch medicament (1) is filled in a patch body (2), and the patch body (2) selectively positions and applies the patch medicament (1) to the surface of the set acupoint of a human body; the patch body (2) at least comprises a tissue contact layer (3) and a water absorption layer (6), wherein the tissue contact layer (3) is used for accommodating the patch medicament (1), and the water absorption layer (6) is mounted on the surface of the tissue contact layer (3) in a manner of being capable of absorbing water overflowing from the inner space of the tissue contact layer (3) for accommodating the patch medicament (1); and the water absorption layer (6) surrounds the opening position of the tissue contact layer (3) for filling the patch medicament (1).

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine patches, in particular to a transdermal patch for treating liver cirrhosis ascites and a preparation method thereof. Background technique [0002] Liver cirrhosis is an advanced disease of many liver diseases, and its formation and development often go through a long-term process, and ascites is a manifestation of its decompensation. Due to the repeated degeneration, necrosis and abnormal regeneration of liver tissue, the structure and function of the liver have been severely damaged. Therefore, it is still difficult to significantly improve the metabolism and synthesis function of the liver while reducing ascites within a short course of treatment. The formation of ascites is due to the deficiency of the human body's righteousness, the dysfunction of the liver, spleen, and kidney, and the stagnation of qi, congestion, and water and drink in the abdomen. Because it is easy to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61M37/00A61P1/16A61K9/70A61K47/10A61K31/045
CPCA61K36/481A61K36/39A61K36/708A61K36/47A61K36/9066A61K36/8994A61K36/539A61K36/736A61K36/286A61K31/045A61K9/7023A61K47/10A61P1/16A61M37/00A61M2037/0007
Inventor 吴晶蒋荆萍
Owner 吴晶