Application of serum amyloid A2 in preparation of kit for detecting lung cancer

A serum starch and kit technology, applied in the fields of biotechnology and medicine, can solve the problem of SAA2 lung cancer

Pending Publication Date: 2021-07-30
上海依赛洛森生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] At present, there is no commercial kit for SAA2 screening and clinical staging of lung cancer

Method used

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  • Application of serum amyloid A2 in preparation of kit for detecting lung cancer

Examples

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Embodiment 1

[0055] Example 1 Application of Serum Amyloid A2 in the Preparation and Detection of Lung Cancer Early Screening and Clinical Staging Kit

[0056] 1. Test material

[0057] Blood samples were collected from 90 lung cancer patients and 61 healthy individuals. All human peripheral blood samples to be used for ELISA detection were centrifuged at 1600g within 2 hours at 4°C for 15 minutes, then the supernatant was transferred to a new EP tube, marked, and quickly stored at -80°C.

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Abstract

The invention discloses application of serum amyloid A2 in preparation of a kit for detecting lung cancer, and belongs to the field of biotechnology and medicine. The invention particularly discloses the application of serum amyloid protein A2 as a molecular marker in preparation of a kit or a reagent for detecting lung cancer. The serum amyloid protein A2 as the molecular marker is used for early screening and clinical staging of lung cancer. Through test verification, the invention reveals that the high expression of the SAA2 gene is closely associated with the clinical staging of the lung cancer for the first time, discovers that the SAA2 can be used as a marker for detecting tissues and plasma samples of NSCLC patients, and develops a rapid detection reagent or kit for clinical early screening and clinical staging of the lung cancer, thereby providing a new means for diagnosis of the lung cancer.

Description

technical field [0001] The invention relates to the fields of biotechnology and medicine, in particular to the application of serum amyloid A2 in the preparation of a kit for detecting lung cancer. Background technique [0002] Lung cancer is currently one of the most common malignant tumors, and it is also the tumor with the fastest increasing morbidity and mortality worldwide. About 1.2 million patients are diagnosed with lung cancer and 1.1 million people die of lung cancer every year. Lung cancer can be divided into two categories based on its histopathology: small cell lung cancer and non-small cell lung cancer. Non-small cell lung cancer includes squamous cell carcinoma, adenocarcinoma, and large cell carcinoma. [0003] So far, there is still a lack of effective molecular detection methods for early screening and clinical staging of lung cancer. The development of new early screening and diagnostic techniques has become a major scientific problem to be solved urgent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/574G01N33/68G01N33/577G01N33/58G01N33/543
CPCG01N33/57423G01N33/57488G01N33/68G01N33/577G01N33/581G01N33/54393G01N2333/775
Inventor 孟民杰张舒林魏慧敏万武
Owner 上海依赛洛森生物医药有限公司
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