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Tooth root surface treating agent

A technology of surface treatment agent and tooth root, applied in the direction of dental preparations, dentistry, dental prosthesis, etc., can solve the problems of poor treatment effect and achieve good reattachment effect

Active Publication Date: 2021-08-06
WUHAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The main purpose of the present invention is to provide a novel and efficient tooth root surface treatment agent for the shortcomings of the existing root surface treatment effect.

Method used

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Examples

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Effect test

Embodiment 1

[0031] A tooth root surface treatment agent, it comprises decontamination composition 1 and regeneration composition 2; Concrete preparation steps are as follows:

[0032] 1) Prepare decontamination composition 1, weigh each component according to the proportion, each component and its mass percentage are: Poloxamer 407 (finished product) 15%, Triton X-114 1%, propylene glycol 5%, 1% glycerin, 2% tetrahydropiperine, 1% sycamore enol, and the rest is deionized water; mix the weighed components uniformly to prepare the decontamination composition 1;

[0033] 2) Prepare regeneration composition 2, weigh each component according to the proportion, and each component and its mass percentage are: chlorhexidine gluconate 1%, EMD (enamel matrix derivative) 5%, BMP2 (bone morphogenic protein 2) 5%, BMP4 (bone morphogenic protein 4) 10%, FGF2 (fibroblast growth factor 2) 1%, minocycline hydrochloride 2%, polyethylene glycol diacrylate 0.4%, the rest is deionized water ; Mix the weighed...

Embodiment 2

[0053] A tooth root surface treatment agent, it comprises decontamination composition 1 and regeneration composition 2; Concrete preparation steps are as follows:

[0054] 1) Prepare decontamination composition 1, weigh each component according to the proportion, each component and its mass percentage are: Poloxamer 407 (finished product) 15%, Triton X-114 1%, propylene glycol 5%, 1% glycerin, 2% tetrahydropiperine, 2% saruenol, and the rest is deionized water; mix the weighed components uniformly to prepare composition 1;

[0055] 2) Prepare regeneration composition 2, weigh each component according to the proportion, each component and its mass percentage are: chlorhexidine gluconate 2%, EMD (enamel matrix derivative) 10%, BMP2 (bone morphogenic protein 2) 10%, BMP4 (bone morphogenic protein 4) 10%, FGF2 (fibroblast growth factor 2) 1%, minocycline hydrochloride 2%, polyethylene glycol diacrylate 0.4%, the rest is deionized water ; Mix the weighed components uniformly to pr...

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Abstract

The invention discloses a tooth root surface treating agent. The tooth root surface treating agent comprises a decontamination composition 1 and a regeneration composition 2, wherein the decontamination composition 1 comprises the ingredients in percentage by mass: 13%-17% of poloxamer 407, 1%-3% of Triton X-114, 3%-7% of propylene glycol, 1%-2% of glycerine, 1%-2% of tetrahydropiperine, 1%-3% of malloperenol and the balance of water; the regeneration composition 2 comprises the ingredients in percentage by mass: 0.5%-2% of chlorhexidine gluconate, 15%-31% of regenerant, 1%-3% of minocycline hydrochloride, 0.3%-0.5% of polyethylene glycol diacrylate and the balance of water; and the regenerant is composed of an enamel matrix derivative, a bone morphogenetic protein 2, a bone morphogenetic protein 4 and fibroblast growth factor 2. The tooth root surface treating agent can achieve efficient cleaning of the surface of a tooth root, can be used for improving the reattachment effect of fibroblasts of gums and is applicable to popularization and application.

Description

technical field [0001] The invention belongs to the technical field, in particular to a tooth root surface treatment agent Background technique [0002] Healthy gums cover the surface of the entire tooth root, protecting the tooth root and stabilizing the tooth. Periodontitis is the inflammation and destruction of the tissues around the teeth in the oral cavity. Gingival recession is an important symptom of periodontitis, causing the gum on the surface of the root to shift downward. Gingival recession exposes the surface of the tooth root that was originally covered by the gum, which not only causes aesthetic problems, but also makes the patient look old; it can also cause soreness and sensitivity of the tooth root; further development of gingival recession leads to a large amount of damage to the tooth supporting tissue, and eventually leads to loosening and shedding of the gums. After the gingiva on the root surface recedes, it will cause some other problems: For example...

Claims

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Application Information

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IPC IPC(8): A61K6/52
CPCA61K6/52
Inventor 杨栋文昶李四红王水凝余文娟
Owner WUHAN UNIV
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