Method and kit for identifying state of prostate cancer

A state-of-the-art technology for prostate cancer, applied in the direction of biochemical equipment and methods, microbial determination/testing, DNA/RNA fragments, etc.
CN113234820APending Publication Date: 2021-08-10BEIJING EXELLON MEDICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING EXELLON MEDICAL TECH CO LTD
Publication Date
2021-08-10

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Abstract

Provided herein is a method of identifying the state of prostate cancer in a subject, and the method comprises the steps: 1) detecting the methylation level of a biomarker gene in a biological sample from the subject wherein the biomarker gene is selected from one or more of the following genes: APC, CCND2, CDH1, GSTP1, MCAM, PENK, PITX2, PTGS2, RARB, and RASSF1A; 2) comparing the methylation level detected in the step 1) with the normal methylation level of the corresponding biomarker gene in the population to determine the state of prostate cancer in the subject. Also provided herein are kits for identifying the state of prostate cancer in a subject. The method and the kit provided by the invention provide a rapid, reliable and accurate new way for prediction, diagnosis and evaluation of prostate cancer.
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Description

technical field

[0001] The present invention relates to methods and kits for identifying prostate cancer status in a subject. Background technique

[0002] Prostate cancer is the most common malignant tumor of the male reproductive system, and it is the second leading cause of cancer death in men in the United States. In recent years, the incidence of prostate cancer in my country has increased significantly. Prostate cancer has leapt to the sixth most common tumor in Chinese men, and its growth rate is the fastest among all male tumors. The cure rate of prostate cancer detected in the early stage is as high as 95%, while the 5-year survival rate in the late stage is less than 30%. The prevention and treatment situation of prostate cancer in China is very severe today.

[0003] At present, the diagnosis of prostate cancer mainly includes PSA blood test, digital rectal examination and ultrasound. However, in recent years, studies have reported that the accuracy of prostate ...

Claims

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