1 results about "GSTP1" patented technology

The present application relates to the field of biotechnology, and application of a kuding tea and its extract and a product for preventing or treating hypertension. The product has the following effects: reducing the abundance of staphylococcus aureus (SA) in the intestinal tract or / and regulating the composition of the intestinal flora; reducing the level of at least one exotoxin secreted by SA in the body; up-regulating the expression of at least one of glutathione S-transferase and glutathione S-transferase P1 in the hypothalamic paraventricular nucleus. The present application also provides application of GSTM2 / GSTP1 as a target point in a product for preventing or treating hypertension. The present application is applied to a product for up-regulating the antioxidant defense (GSTM2 / GSTP1) of the hypothalamic paraventricular nucleus (PVN) through intestinal SA-exotoxin, and is further applied to prevention and treatment of hypertension. The present application provides a new target point for intervention in reducing blood pressure, and thus prepares a new product such as a drug for preventing and treating hypertension.