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Photoacoustic microscopic endoscopic imaging system

An imaging system and photoacoustic microscopy technology, applied in the field of medical imaging, can solve the problems of inability to obtain blood oxygen saturation information and increase of wavelength switching time, improve spatial resolution and imaging quality, and overcome the problem of long wavelength switching time Effect

Pending Publication Date: 2021-09-07
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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  • Abstract
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  • Application Information

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Problems solved by technology

At present, in the photoacoustic imaging system for measuring blood oxygen, most of the multi-wavelength pulsed laser sources switch wavelengths through manual control or host computer programs, which greatly increases the wavelength switching time and makes it impossible to obtain relatively complete blood oxygen saturation information.

Method used

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  • Photoacoustic microscopic endoscopic imaging system
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Embodiment Construction

[0014] Such as figure 1 As shown, a photoacoustic micro-endoscopic imaging system includes: a dual-wavelength modulation device, a micro-endoscopic imaging device, and a PC upper computer. The dual-wavelength modulation device is used to generate the first excitation light and the second excitation light, the micro-endoscopic imaging device is used for excitation and detection of photoacoustic signals, and the PC host computer is used for image reconstruction.

[0015] The dual-wavelength modulation device includes a 532nm pulsed laser 1, a first half-wave plate 2, a polarization fractional prism 3, a second half-wave plate 4, a first fiber coupler 5, a 5m polarization-maintaining fiber 6, a second fiber coupler 7, a second One filter 8, the first neutral density filter 9, the first plane mirror 10, the third half-wave plate 11, the third fiber coupler 12, 50m single-mode fiber 13, the fourth fiber coupler 14, the second filter Sheet 15, second neutral density filter 16, seco...

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Abstract

The invention discloses a photoacoustic microscopic endoscopic imaging system. The photoacoustic microscopic endoscopic imaging system comprises a dual-wavelength modulation device, a microscopic endoscopic imaging device and a PC (Personal Computer) upper computer; the dual-wavelength modulation device is used for generating first exciting light and second exciting light; the microscopic endoscopic imaging device is used for exciting and detecting photoacoustic signals; and the PC upper computer is used for image reconstruction. A photoacoustic scanning probe is miniaturized, and the photoacoustic imaging contrast ratio and the resolution ratio are improved.

Description

technical field [0001] The invention relates to the technical field of medical imaging, in particular to a photoacoustic microendoscopic imaging system. Background technique [0002] The photoacoustic effect refers to the phenomenon that after an object is subjected to light with periodically changing intensity, it will expand with heat and contract with cold due to the periodic temperature change inside the object, thereby generating ultrasonic waves. As a new type of biomedical optical imaging technology, photoacoustic imaging has bright application prospects. A variety of photoacoustic imaging systems have been developed for different application scenarios. Blood oxygen saturation is the percentage of the capacity of oxyhemoglobin in the blood to the total hemoglobin capacity that can be combined with oxygen. It is not only an important indicator for estimating the oxygen-carrying capacity of hemoglobin, but also an important physiological parameter of the respiratory cy...

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Application Information

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IPC IPC(8): A61B5/1455
CPCA61B5/14552A61B5/0095
Inventor 李韪韬王飞龙王康陶玲钱志余徐昊星陈阳
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS