Nucleic acid detector

A detector and nucleic acid technology, applied in the field of nucleic acid detectors, can solve the problems of bulkiness, high cost, and complicated operation.

Pending Publication Date: 2021-09-10
HEMOSMART MEDICAL TECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing nucleic acid detectors are aimed at horizontal microfluidic chips, which are complex in structure, large in size and occupy a lot of space, are heavy, expensive, and complicated to operate.

Method used

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Embodiment Construction

[0065] The preferred embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, so that the advantages and features of the present invention can be more easily understood by those skilled in the art. It should be noted here that the descriptions of these embodiments are used to help understand the present invention, but are not intended to limit the present invention.

[0066] According to one embodiment of the present invention, a nucleic acid detector is provided, which can automatically perform nucleic acid extraction, amplification and detection. Figure 1 to Figure 3 shows the nucleic acid detector, Figure 4 A microfluidic chip 100 suitable for the nucleic acid detector is shown. The microfluidic chip 100 is a vertical microfluidic chip, that is, its height is at least greater than its width, and it is in the shape of a vertical plate as a whole. The sample inlet is located on the upper part of the microfluidic ...

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Abstract

The invention discloses a nucleic acid detector which comprises a base, a chip mounting assembly, a heating device, an optical detection device and a mechanical arm assembly; the chip mounting assembly is arranged on the left side part of the base and comprises a box body, a chip groove for accommodating a micro-fluidic chip is formed in the box body, and the chip groove is provided with a groove opening facing upwards; the heating device is arranged on the front side or the rear side of the chip mounting assembly; the optical detection device is arranged below the chip mounting assembly and is provided with an emitted light emitting part and an exciting light receiving part which are used for facing the lower end part of the micro-fluidic chip; the lower end part of the box body is provided with a hollow part capable of allowing emitted light to enter the chip groove and allowing exciting light to be emitted out of the chip groove; and the mechanical arm assembly comprises a mechanical arm capable of moving in the left-right direction, the mechanical arm is provided with a fork-shaped piece, and the fork-shaped piece is provided with a joint groove allowing the end of a piston of the micro-fluidic chip to be clamped in. The nucleic acid detector is compact in structure and small in size.

Description

technical field [0001] The invention belongs to the technical field of nucleic acid detection and relates to a nucleic acid detection instrument. Background technique [0002] Nucleic acid amplification detection technology is to provide in vitro amplification conditions for nucleic acid fragments to make them exponentially amplify in large quantities and add fluorescent dyes or fluorescent markers during the nucleic acid amplification process, and use optical devices to detect the strength of fluorescent signals. The process of obtaining nucleic acid amplification results through the analysis of fluorescent signals. During the nucleic acid amplification reaction, the reaction system needs to be heated. In addition, the nucleic acid detector can integrate nucleic acid amplification and detection. When the detection chip (usually a microfluidic chip) is placed in the nucleic acid detector, the reaction chamber of the detection chip (usually an amplification reaction chamber)...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/64C12M1/34C12M1/38C12M1/00C12Q1/68
CPCG01N21/6428C12Q1/68G01N2021/6439
Inventor 颜菁翟锋俞涛
Owner HEMOSMART MEDICAL TECH LTD
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