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Eye iontophoresis drug delivery device and method using annular electrode

A technology of iontophoresis and ring electrodes, which is applied in electrotherapy, medical equipment, physical therapy, etc., and can solve the problems of large delivery area, insufficient uniformity of the electric field of needle-shaped electrodes, and complex structures.

Inactive Publication Date: 2021-09-21
MINZU UNIVERSITY OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this type of device does not need to be adsorbed on the cornea, which reduces the damage to the eyes, the delivery area is still too large
In addition, some of these devices need to be pressed against the eyes with the help of external force all the time, the uniformity of the electric field formed by some needle-shaped electrodes is not good enough, and some have complex structures.

Method used

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  • Eye iontophoresis drug delivery device and method using annular electrode
  • Eye iontophoresis drug delivery device and method using annular electrode
  • Eye iontophoresis drug delivery device and method using annular electrode

Examples

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Embodiment Construction

[0019] Place the ring electrode (3) under the eyelid, on the sclera. The signal generation module (1) generates a waveform. The specific waveform can be selected according to the specific drug and the effect to be achieved. Generally, a pulse voltage of 2-5V is used. After the selected waveform is amplified by the power amplifier (2), it is loaded onto the ring electrode for electroosmotic drug delivery. The time of electroosmosis is controlled according to the amount of drug required.

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Abstract

The invention discloses an eye iontophoresis drug delivery device and a method. The device comprises a signal generation module, a power amplification module and an annular electrode. The annular electrode is placed below an eyelid and above a sclera, a voltage waveform used for electroosmosis is adjusted, and after the selected waveform is amplified by a power amplifier, the waveform is loaded to the annular electrode for electroosmosis drug delivery. By means of the electroosmosis flexible device, ions penetrate into the eyeball through the sclera, damage to the cornea is reduced, operation is easy and convenient, efficiency is improved, and a better electroosmosis effect is achieved.

Description

technical field [0001] The invention relates to the technical field of electronic devices, in particular to an electroosmotic drug delivery device and method. Background technique [0002] With the development of our society and the advancement of science and technology, the treatment of many posterior segment diseases has been paid more and more attention by everyone. However, due to the special physiological structure of the eye, the treatment of posterior segment diseases has always been a difficult problem in the field of ophthalmology. Invasive drug delivery is a common method, but its duration is short, it cannot achieve effective drug concentration, and it can also cause damage to the eyeball and cause infection. Therefore, it is more ideal to use a drug delivery device to allow the drug to penetrate to the required area. Location. However, due to the poor permeability of eye tissue and the barriers of some biological structures, the drug penetration effect is poor....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00A61N1/36A61F9/00
CPCA61M37/00A61N1/36046A61F9/0008A61M2037/0007A61M2210/0612A61M2210/005
Inventor 张宇识刘琦张智伟
Owner MINZU UNIVERSITY OF CHINA