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Food or pharmaceutical composition for improving cognitive function and memory, containing probiotic or containing omega-3-containing probiotic

A technology for improving cognition and cognitive function, which is applied in the field of compositions for improving cognitive function and memory, and can solve the problems of negligible improvement of memory and insufficient improvement of cognitive function

Inactive Publication Date: 2021-10-12
比菲德股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, until now, little research has been done on the effects of omega-3 fatty acids and probiotic intake on improving intestinal function, including the intestinal flora and the intestinal immune system, and its correlation. The effect of omega-3 fatty acids and probiotics on memory improvement and improved cognitive function in the elderly population, a major player in the age of aging, is very understudied

Method used

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  • Food or pharmaceutical composition for improving cognitive function and memory, containing probiotic or containing omega-3-containing probiotic
  • Food or pharmaceutical composition for improving cognitive function and memory, containing probiotic or containing omega-3-containing probiotic
  • Food or pharmaceutical composition for improving cognitive function and memory, containing probiotic or containing omega-3-containing probiotic

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0072] Experimental Example 1: Population Sociological Characteristics

[0073] In the present invention, healthy elderly people over 65 years of age were recruited from the Seoul area and the Bundang area, and appropriate research participants were selected through a pre-screening test in advance. The intervention study was conducted for a total of 12 weeks in the Seoul area from May to August 2018, and in the Bundang area from June 2018 to March 2019. A total of 161 people were registered in Seoul and Bundang area, according to the selection and exclusion criteria of study participants (excluding those who had been taking antibiotics, anti-inflammatory agents, gastrointestinal disease drugs, anticoagulants in the past three months, A total of 102 people who continued to take lactic acid bacteria and omega-3 fatty acid supplements within a month, and people with food allergies (soy allergy) were selected for intervention research.

[0074] The final selected study participan...

Embodiment 1

[0087] Example 1: Experiments on whether there is a change in the aging-related index through the intake of probiotics or omega-3

[0088] In consideration of the age of the subject persons of the present invention, it was checked through experiments whether aging-related indicators were changed by the intake of probiotics or the supplementary intake of omega-3 fatty acids. As aging progresses, naive T cells in the T cell subpopulation in the blood decrease, while memory T cells increase.

[0089] Thus, the composition of T cell subsets was confirmed after supplemental intake of probiotics or omega-3 fatty acids. When observing CD4 in blood + Original CD4 T cells of T cells and CD4 effector memory T cells (CD4 effector memory T cells, CD4T EM cell), in all groups of the placebo control group, the probiotic group, and the probiotic+omega-3 fatty acid group, no significant change over time was observed. However, if image 3 As shown, CD4 central memory T cells (CD4 central ...

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Abstract

The invention discloses a food or pharmaceutical composition for improving cognitive function and memory, containing a probiotic or containing a probiotic containing omega-3. The present invention relates to a composition for improving cognitive function and memory, which comprises a probiotic bacterium or omega-3, and the probiotic bacterium of (Bifidobacterium bifidum) BGN4 (KCCM12754P) or (Bifidobacterium longum) BORI (KCCM-10492) contains omega-3, and has an excellent cognitive function and memory improving effect, and thus can be used as food, health food, and a pharmaceutical product.

Description

technical field [0001] The present invention relates to a composition comprising probiotics or omega-3 for improving cognitive function and memory, more specifically, relates to a composition comprising Bifidobacterium bifidum (Bifidobacterium bifidum) BGN4 (KCCM12754P) strain and Bifidobacterium longum Food composition or pharmaceutical composition for improving cognitive function and memory of Bifidobacterium longum BORI (KCCM-10492) strain. Background technique [0002] Beginning early in life, through childhood and adolescence, and into adulthood, health problems occur at every transitional time in life. Health risk factors that threaten health in each life transition period are different, and disease prevention through diagnosis and treatment of corresponding risk factors is essential for maintaining a healthy life. [0003] Elderly, on the other hand, unlike young adults, mostly have multiple diseases caused by aging at the same time, and usually progress in a non-spe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/745A61P25/00A23L33/135
CPCA61K35/745A61P25/00A23L33/135A23V2002/00A23V2400/517A23V2400/533A23V2200/322
Inventor 池根亿朴明洙
Owner 比菲德股份有限公司