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An aerosol for skin repair after sun exposure and its preparation method

A technology of skin repair and aerosol, which is applied in the field of medical cosmetology, can solve the problems of ultraviolet inflammatory reaction cell damage, etc., and achieve the effects of reducing skin burning, swelling and pain, accelerating reconstruction, and relieving skin symptoms

Active Publication Date: 2022-06-28
赵月
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that existing post-sun repair products are difficult to effectively deal with the inflammatory response and cell damage caused by ultraviolet rays, the present invention provides an aerosol for post-sun skin repair and its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] This embodiment provides an aerosol for skin repair after sun exposure. The aerosol includes the following components by weight: 0.5 parts of adipose stem cell exosomes, 12 parts of drug-loaded nanoliposomes, and a molecular weight of 0.10 part of 1000-1400kDa hyaluronic acid, 0.05 part of hyaluronic acid with a molecular weight of 20-300kDa, 1 part of allantoin, 10 parts of glycerin and 76.35 parts of deionized water.

[0028] In this example, the mass ratio of egg yolk phosphatidylcholine, cholesterol and the pharmaceutical composition in the drug-loaded nanoliposomes is 70:20:10, wherein tea polyphenols, astaxanthin, bisabolol, The mass ratio of spiramide-3, vitamin E and peppermint oil is 3:2:1:2:1:1.

Embodiment 2

[0030] This embodiment provides an aerosol for skin repair after sun exposure. The aerosol includes the following components by weight: 0.1 part of adipose stem cell exosomes, 10 parts of drug-loaded nanoliposomes, and a molecular weight of 0.15 part of 1000-1400kDa hyaluronic acid, 0.01 part of hyaluronic acid with molecular weight of 20-300kDa, 0.5 part of allantoin, 5 parts of glycerin and 84.24 parts of deionized water.

[0031] In this example, the mass ratio of egg yolk phosphatidylcholine, cholesterol and the pharmaceutical composition in the drug-loaded nanoliposomes is 68:20:12, in which tea polyphenols, astaxanthin, bisabolol, The mass ratio of spiramide-3, vitamin E and peppermint oil is 2:1:3:1:2:1.

Embodiment 3

[0033] This embodiment provides an aerosol for skin repair after sun exposure, the aerosol includes the following components by weight: 1 part of adipose stem cell exosomes, 15 parts of drug-loaded nanoliposomes, and a molecular weight of 0.05 part of 1000-1400kDa hyaluronic acid, 0.03 part of hyaluronic acid with a molecular weight of 20-300kDa, 0.8 part of allantoin, 8 parts of glycerin and 75.12 parts of deionized water.

[0034] In this example, the mass ratio of egg yolk phosphatidylcholine, cholesterol and the pharmaceutical composition in the drug-loaded nanoliposomes is 65:20:15, and the pharmaceutical composition contains tea polyphenols, astaxanthin, bisabolol, The mass ratio of spiramide-3, vitamin E and peppermint oil is 1:2:2:3:1:1.

[0035]The adipose stem cell exosomes used in Examples 1-3 are human adipose stem cell exosomes with a particle size of 20-200 nm, which are physiologically active substances secreted by cells during physiological activities. The main...

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Abstract

The invention relates to an aerosol for repairing skin after sun exposure and a preparation method thereof, belonging to the technical field of medical cosmetology. In order to solve the problem that the existing post-sun repair products are difficult to effectively deal with the inflammatory response and cell damage caused by ultraviolet rays, the present invention provides an aerosol for post-sun skin repair. The main components include fat stem cell exosomes, drug-loaded Nanoliposomes, Hyaluronic Acid, Allantoin, Glycerin and Deionized Water. The present invention uses adipose stem cell exosomes and drug-loaded nanoliposomes with anti-inflammatory, sedative, and free-radical-scavenging effects as main functional components to help damaged skin cells quickly repair damage, eliminate redness, and provide skin cells with post-sunburn reconstruction. Nutrition. The various components in the aerosol of the present invention play a synergistic effect after compounding, replenish sufficient water for damaged skin, restore cell function, promote skin tissue metabolism, and remove oxygen free radicals. At the same time, each component Mild and non-irritating, safe and non-toxic side effects.

Description

technical field [0001] The invention belongs to the technical field of medical cosmetology, and particularly relates to an aerosol for skin repairing after sun exposure and a preparation method thereof. Background technique [0002] The two kinds of penetrating ultraviolet rays, UVA and UVB in the sun, will directly reach the dermis of the skin, causing redness, burning, heat and pain in the irradiated skin of people with allergic constitution. allergy. At the same time, UV radiation can also lead to a sharp increase in free radicals in the body, causing localized skin wrinkles, pigmentation and cell damage. [0003] Within 72 hours after sun exposure is the repair period for skin injuries, and 6-8 hours after exposure is the best time for repair. Common post-sun skin repairs are mostly cold compresses to calm and replenish moisture, and it is difficult to effectively deal with the inflammatory response and cell damage caused by ultraviolet rays. Moreover, most of the aft...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/04A61K8/14A61K8/34A61K8/35A61K8/49A61K8/67A61K8/68A61K8/73A61K8/92A61Q19/00C12N5/0775B82Y5/00B82Y40/00
CPCA61K8/99A61K8/735A61K8/4946A61K8/345A61K8/922A61K8/498A61K8/35A61K8/34A61K8/68A61K8/678A61K8/046A61K8/14A61Q19/004A61Q19/08C12N5/0667B82Y5/00B82Y40/00A61K2800/82A61K2800/5922A61K2800/413
Inventor 赵月肖志波
Owner 赵月
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