Aerosol for after-sun skin repair and preparation method thereof

A technology of skin repair and aerosol, which is applied in the field of medical cosmetology, can solve the problems of ultraviolet inflammatory reaction cell damage, etc., and achieve the effect of reducing skin burning, swelling and pain, removing oxygen free radicals, and high purity

Active Publication Date: 2021-11-09
赵月
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to solve the problem that existing post-sun repair products are difficult to effectively deal with the inflammatory response and cell damage caused by ultraviolet rays, the present invention provides an aerosol for post-sun skin repair and its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] This embodiment provides an aerosol for skin repair after sun exposure, the aerosol includes the following components by weight: 0.5 parts of fat stem cell exosomes, 12 parts of drug-loaded nanoliposomes, and a molecular weight of 0.10 part of hyaluronic acid of 1000-1400 kDa, 0.05 part of hyaluronic acid of molecular weight of 20-300 kDa, 1 part of allantoin, 10 parts of glycerin and 76.35 parts of deionized water.

[0028] In this example, the mass ratio of egg yolk phosphatidylcholine, cholesterol and pharmaceutical composition in drug-loaded nanoliposomes is 70:20:10, wherein tea polyphenols, astaxanthin, bisabolol, The mass ratio of ceramide-3, vitamin E and peppermint oil is 3:2:1:2:1:1.

Embodiment 2

[0030] This embodiment provides an aerosol for repairing skin after sun exposure. The aerosol includes the following components in parts by weight: 0.1 parts of fat stem cell exosomes, 10 parts of drug-loaded nanoliposomes, and a molecular weight of 0.15 part of hyaluronic acid of 1000-1400 kDa, 0.01 part of hyaluronic acid of molecular weight of 20-300 kDa, 0.5 part of allantoin, 5 parts of glycerin and 84.24 parts of deionized water.

[0031] In this example, the mass ratio of egg yolk phosphatidylcholine, cholesterol and pharmaceutical composition in drug-loaded nanoliposomes is 68:20:12, wherein tea polyphenols, astaxanthin, bisabolol, The mass ratio of ceramide-3, vitamin E and peppermint oil is 2:1:3:1:2:1.

Embodiment 3

[0033] This embodiment provides an aerosol for skin repair after sun exposure, the aerosol includes the following components by weight: 1 part of fat stem cell exosomes, 15 parts of drug-loaded nanoliposomes, and a molecular weight of 0.05 part of hyaluronic acid of 1000-1400 kDa, 0.03 part of hyaluronic acid of molecular weight of 20-300 kDa, 0.8 part of allantoin, 8 parts of glycerin and 75.12 parts of deionized water.

[0034] In this embodiment, the mass ratio of egg yolk phosphatidylcholine, cholesterol and pharmaceutical composition in drug-loaded nanoliposomes is 65:20:15, wherein tea polyphenols, astaxanthin, bisabolol, The mass ratio of ceramide-3, vitamin E and peppermint oil is 1:2:2:3:1:1.

[0035]The adipose stem cell exosomes used in Examples 1-3 are human adipose stem cell exosomes with a particle size of 20-200nm, which are physiologically active substances secreted by cells during physiological activities. The main functional components include protein substan...

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Abstract

The invention relates to an aerosol for after-sun skin repair and a preparation method thereof, and belongs to the technical field of medical cosmetology. In order to solve the problem that an existing after-sun repair product is difficult to effectively cope with inflammatory response and cell damage caused by ultraviolet rays, the invention provides the aerosol for after-sun skin repair, which mainly comprises an adipose-derived stem cell exosome, a drug-loaded nano-liposome, hyaluronic acid, allantoin, glycerol and deionized water. According to the invention, the adipose-derived stem cell exosome and the drug-loaded nano-liposome with the effects of diminishing inflammation, calming and scavenging free radicals are used as main functional components; damaged skin cells are helped to rapidly repair damage and eliminate redness and swelling; and nutrition is provided for skin cell reconstruction in the later sunburn period. All the components in the aerosol disclosed by the invention have a synergistic effect after being compounded; sufficient water is supplemented for damaged skin; the cell function of the damaged skin is recovered; metabolism of skin tissue is promoted; oxygen free radicals are removed; and meanwhile, all the components are mild, free of irritation, safe and free of toxic and side effects.

Description

technical field [0001] The invention belongs to the technical field of medical cosmetology, and in particular relates to an aerosol for skin repair after sun exposure and a preparation method thereof. Background technique [0002] The two penetrating ultraviolet rays in the sun, UVA and UVB, will directly reach the dermis of the skin, causing redness, burning, heat, and pain in the irradiated skin of people with allergies. This is what is often called solar dermatitis in medicine, that is, ultraviolet rays. allergy. At the same time, ultraviolet radiation can also cause a sharp increase in free radicals in the body, causing local skin wrinkles, pigmentation and cell damage. [0003] The repair period for skin injuries is within 72 hours after sun exposure, and the best time for repair is 6-8 hours after sun exposure. Common post-sun skin repairs are mostly cold compresses to calm and replenish water, which is difficult to effectively deal with the inflammatory response and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/99A61K8/04A61K8/14A61K8/34A61K8/35A61K8/49A61K8/67A61K8/68A61K8/73A61K8/92A61Q19/00C12N5/0775B82Y5/00B82Y40/00
CPCA61K8/99A61K8/735A61K8/4946A61K8/345A61K8/922A61K8/498A61K8/35A61K8/34A61K8/68A61K8/678A61K8/046A61K8/14A61Q19/004A61Q19/08C12N5/0667B82Y5/00B82Y40/00A61K2800/82A61K2800/5922A61K2800/413
Inventor 赵月肖志波
Owner 赵月
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