Driving circuit, driving method and microfluidic substrate

Abstract

The invention discloses a driving circuit, a driving method and a microfluidic substrate. The driving circuit comprises a first switch unit, a second switch unit, a reset unit, a first capacitor and a second capacitor, wherein the driving process comprises a first stage and a second stage, the first switch unit is switched on in the first stage, a first voltage signal is transmitted to a first node, the second switch unit is switched on, a second voltage signal is input to the output end of the driving circuit, the driving circuit outputs an alternating-current signal, and the alternating-current signal output time is maintained after the first capacitor is charged; and in a second stage, the first switch unit is switched off, meanwhile, an effective signal output by a second scanning signal end controls the reset unit to be switched on, a third voltage signal is input to the output end of the driving circuit for resetting, the driving circuit outputs a direct-current signal, and the direct-current signal output time is maintained after the second capacitor is charged. According to the driving circuit the output end of the driving circuit is switched between a high-frequency alternating-current signal and a direct-current signal, the hysteresis residual problem of the microfluidic substrate is solved, and the driving performance is enhanced.

Description

Technical field [0001] The present invention relates to the field of microfluidic control technology, and more particularly, relates to a circuit for a microfluidic substrate and a driving method. Background technique [0002] Microfluidic (a Microfluidics) technology refers to the use of micro-channels (the size of several tens to hundreds of microns) for a minute or manipulating the fluid (A nanoliter volume liters) technique. Microfluidic technology can be applied to the field of genetic engineering, disease diagnosis and drug discovery, cell analysis, environmental monitoring and protection, health quarantine, forensic and so on. [0003] In the field of digital control technology based on electrical microfluidic wetting (EWOD, electrowetting-on-dielectric), the microfluidic circuit board commonly used to control a voltage drive electrode, so that an electric field is formed between adjacent drive voltage, the droplets mobile driven by an electric field. [0004] Currently, i...

AI Technical Summary

Problems solved by technology

In the passive driving scheme, the driving electrode is directly connected to the signal, and it can be driven by an AC signal or a DC signal. For passive driving, if a DC signal is used for driving, the dielectric layer will be charged and accumulated, which will easily lead to hysteresis and residual droplets. The driving ability of biochemical reagents is weak, which affects the performance and application of the chip; if the AC signal is used for passive driving, the number of signals required is large, that is, more signal lines are required to transmit signals, which will increase the difficulty of production and cost

[0005]So the existing technology is more and more inclined to the development of active driving scheme, and for the general active driving scheme of 1T1C, the signal on the driving electrode depends on the storage Capacitor retention, unable to achieve AC output within one frame time; even if the positive and negative voltages are provided in different frames to provide an AC-like effect, but its frequency is limited by the frame frequency, which cannot meet the needs of digital microfluidics (usually 0.1 ~100kHz, preferably 1-10kHz)

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