A kind of prescription for removing blood stasis and lowering turbidity for treating gout

A technology for removing blood stasis and reducing turbidity, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, metabolic diseases, etc., and can solve the problems of acute recurrence of gout symptoms, high incidence of adverse reactions, and inability to effectively avoid gout recurrence.

Active Publication Date: 2022-07-05
陕西省中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although Western medicine can effectively reduce uric acid levels, control acute attacks, and relieve clinical symptoms in terms of treatment, there are still some deficiencies: ①The timing, target and possible adverse effects of uric acid lowering are still controversial; ②In clinical practice, the initial application of urate-lowering drugs is likely to lead to acute recurrence of gout symptoms, and lowering urate can not effectively prevent the recurrence of gout. Some studies have shown that febuxostat and allopurinol are effective in the treatment of urate-lowering for one year. , 53% of patients had their SUA controlled at ≤6mg·dL -1 , but the recurrence rate of gout is still 63%
③The incidence of adverse reactions of long-term medication is high

Method used

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  • A kind of prescription for removing blood stasis and lowering turbidity for treating gout
  • A kind of prescription for removing blood stasis and lowering turbidity for treating gout
  • A kind of prescription for removing blood stasis and lowering turbidity for treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] A stasis-removing and turbid-removing formula for treating gout is prepared from the following components: stir-fried Atractylodes 15g; Achyranthes sichuanensis 10g; Cortex Phellodendri 9g; Fried Coix Seed 15g; Angelica 9g; Rehmannia glutinosa 10g; Chuanxiong 10g; Atractylodes Rhizoma 15g; Poria 12g; Plantago 15g; Zhigancao 6g; Salvia 12g; Rhubarb 3g.

Embodiment 2

[0012] A prescription for removing blood stasis and lowering turbidity for treating gout, prepared from the following components: 20 g of fried Atractylodes; 15 g of Achyranthes chinensis; 12 g of Treats; 30 g of fried Coix seed; 12 g of Angelica sinensis; 15 g of Rehmannia glutinosa; Poria 15g; Plantago 30g; Zhigancao 9g; Salvia 15g; Rhubarb 6g.

Embodiment 3

[0014] A prescription for removing blood stasis and lowering turbidity for treating gout is prepared from the following components: stir-fried Atractylodes Rhizoma 17.5g; Achyranthes sichuanensis 12.5g; Cortex Phellodendri 10.5g; Chuanxiong 11g; Atractylodes 22.5g; Poria 13.5g; Plantago 22.5g; Zhigancao 7.5g; Salvia 13.5g;

[0015] clinical information:

[0016] Methods: Select patients who meet the diagnostic criteria of gouty arthritis in remission stage, and the TCM diagnosis and syndrome classification belong to the type of spleen deficiency and dampness and blood stasis blocking collaterals. A total of 60 cases were randomly divided into the treatment group (treatment with Quyu Jiangzhuo Decoction, 30 cases). Compared with the control group (benbromarone treatment, 30 cases), the blood uric acid levels, symptom syndrome scores, blood lipids, blood flow levels, safety indicators, curative effects, adverse reactions, etc. of the two groups of patients before and after treat...

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicine preparations, in particular to a formula for removing blood stasis and reducing turbidity for treating gout, which is composed of the following raw materials: stir-fried Atractylodes Rhizoma, Achyranthes chinensis, Phellodendron rhizome, stir-fried Coix seed, Angelica sinensis, Rehmannia glutinosa, Chuanxiong, stir-fried Atractylodes Rhizoma, Poria, psyllium, licorice, salvia, rhubarb. The medicines of the present invention play a role of invigorating the spleen and invigorating the middle, removing blood stasis and removing dampness, consolidating the root and removing blood stasis, and can effectively relieve the symptoms of patients, and can effectively reduce uric acid and blood lipids, have few adverse reactions, are not easy to induce gout, and have satisfactory clinical effects.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a stasis-removing and turbid-removing formula for treating gout. Background technique [0002] Gout is a clinical syndrome in which purine metabolism is abnormal in the body due to metabolic and genetic factors, serum uric acid concentration increases, and monosodium urate crystals are chronically deposited in joint capsule, bursa, cartilage, bone and other tissues, causing inflammatory reactions and clinical syndromes. , which is directly related to hyperuricemia caused by decreased uric acid excretion and / or disorder of purine metabolism, and is the second largest metabolic disease in my country. With the improvement of social and economic level and people's living standards, the prevalence of gout is increasing year by year and the age of onset tends to be younger. If the disease is improperly treated and repeated, it can lead to complications such as u...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P19/06A61P19/02A61P3/06
CPCA61K36/284A61K36/21A61K36/756A61K36/8994A61K36/232A61K36/804A61K36/236A61K36/076A61K36/68A61K36/484A61K36/537A61K36/708A61P19/06A61P19/02A61P3/06A61K2300/00
Inventor 肖洋柯婷杭程祁海燕王高雷王露露师韩菲董丹丹成路平刘厚利钟艺鸣吴宇祥高向宏
Owner 陕西省中医医院
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