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Codonopsis mollis Chipp herba compound composition with anti-allergy and soothing effects, and preparation method and application of Codonopsis mollis Chipp herba compound composition

A technology of Tibetan Codonopsis compound prescription and composition, which is applied in the field of Tibetan Codonopsis compound composition and its preparation, and can solve the problems of high price, poor water solubility and single function

Active Publication Date: 2021-12-24
TIBET UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are many kinds of skin care products that claim to have anti-allergic and soothing effects. Among them, dipotassium glycyrrhizinate, bisabolol and other raw materials are the most common, and their effects are good, but there are also problems such as high price, poor water solubility, and single effect.

Method used

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  • Codonopsis mollis Chipp herba compound composition with anti-allergy and soothing effects, and preparation method and application of Codonopsis mollis Chipp herba compound composition
  • Codonopsis mollis Chipp herba compound composition with anti-allergy and soothing effects, and preparation method and application of Codonopsis mollis Chipp herba compound composition
  • Codonopsis mollis Chipp herba compound composition with anti-allergy and soothing effects, and preparation method and application of Codonopsis mollis Chipp herba compound composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] This example provides a Tibetan Codonopsis compound composition with anti-allergic and soothing effects, including the following raw materials in parts by weight: 40 parts of Tibetan Codonopsis, 30 parts of Tibetan Calamus and 30 parts of hollyhock flowers.

[0027] The preparation method of this composition comprises the following steps:

[0028] (1) Weigh dry Tibetan Codonopsis pilosula, Tibetan calamus and hollyhock flowers in proportion, mix, pulverize, and pass through a 20-mesh sieve; then add 70% ethanol with a volume fraction of 15 times the amount of medicinal materials, and reflux extraction 2 times, each time Extract for 1.5 hours, filter and combine the filtrates, recover ethanol under reduced pressure at 65°C to obtain extract;

[0029] (2) Add hot water 15 times the quality of the extract to the extract obtained in step (1), stir and disperse evenly, and place for 12 hours;

[0030] (3) The material obtained in step (2) was centrifuged at 4000 rpm for 20 ...

Embodiment 2

[0032] This example provides a Tibetan Codonopsis compound composition with anti-allergic and soothing effects, including the following raw materials in parts by weight: 10 parts of Tibetan Codonopsis, 35 parts of Tibetan Calamus and 50 parts of hollyhock flowers.

[0033] The preparation method of this composition comprises the following steps:

[0034] (1) Weigh dry Tibetan Codonopsis pilosula, Tibetan calamus and hollyhock flowers in proportion, mix, pulverize, and pass through a 20-mesh sieve; then add 30% ethanol with a volume fraction of 20 times the mass of the medicinal materials, and reflux extraction once. for 3 hours, filtered to take the filtrate, and recovered ethanol under reduced pressure at 75°C to obtain extract;

[0035] (2) Add hot water 20 times the quality of the extract to the extract obtained in step (1), stir and disperse evenly, and place for 24 hours;

[0036] (3) The material obtained in step (2) was centrifuged at 5000 rpm for 30 minutes, the preci...

Embodiment 3

[0038] This example provides a Tibetan Codonopsis compound composition with anti-allergic and soothing effects, including the following raw materials in parts by weight: 40 parts of Tibetan Codonopsis, 50 parts of Tibetan Calamus and 10 parts of hollyhock flowers.

[0039] The preparation method of this composition comprises the following steps:

[0040] (1) Weigh the dried Tibetan Codonopsis pilosula, Tibetan calamus and hollyhock flower medical materials in proportion, mix, pulverize, and pass through a 20-mesh sieve; After extraction for 1 hour, the filtrates were combined after filtration, and the ethanol was recovered under reduced pressure at 55°C to obtain the extract;

[0041] (2) Add hot water 5 times the quality of the extract to the extract obtained in step (1), stir and disperse evenly, and place for 12 hours;

[0042] (3) The material obtained in step (2) was centrifuged at 3000 rpm for 15 minutes, the precipitate was discarded, the supernatant was taken, concent...

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Abstract

The invention discloses a Codonopsis mollis Chipp herba compound composition with anti-allergy and soothing effects and a preparation method and application of the Codonopsis mollis Chipp herba compound composition. The Codonopsis mollis Chipp herba compound composition is prepared from Codonopsis mollis Chipp herba, Acoruscalamus L roots and Abelmoschus manihot (L.) Medic corolla. The preparation method comprises the following steps that after dried Codonopsis mollis Chipp herba, Acorus calamus L roots and Abelmoschus manihot (L.) Medic corolla medicinal materials are pretreated, ethyl alcohol is added for reflux extraction, obtained filtrate is combined, ethyl alcohol recovery is carried out to obtain an extract, hot water dispersion is carried out on the extract, after centrifugation is carried out, normal pressure concentration and vacuum drying are carried out so as to obtain the Codonopsis mollis Chipp herba compound composition with the anti-allergy and soothing effects. The Codonopsis mollis Chipp herba, the Acoruscalamus L roots and the Abelmoschus manihot (L.) Medic corolla are matched for use, so that the Codonopsis mollis Chipp herba compound composition has a remarkable synergistic effect in the aspects of resisting allergy and soothing.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a compound composition of Tibetan Codonopsis Codonopsis with anti-allergic and soothing effects, a preparation method and application thereof. Background technique [0002] Sensitive skin is considered to be a highly intolerant skin state, which is easily stimulated by various factors and produces a multifactorial syndrome of subjective symptoms such as stinging, burning, tightness, itching, etc., and the skin appearance is normal or accompanied by There was mild desquamation, erythema, and dryness. Sensitive skin and "skin allergy" are two different concepts. Skin allergy is an allergic reaction. After the allergen enters the body, it prompts the body to produce corresponding antibodies, triggering an antigen-antibody reaction, manifested as erythema, pimples, wind Clinical objective signs such as lumps, often accompanied by itching. Sensitive skin usually has a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P17/00A61P37/08A61K8/9794A61K8/9789A61Q19/00
CPCA61K36/344A61K36/888A61K36/185A61P17/00A61P37/08A61K8/9794A61K8/9789A61Q19/005A61K2236/331A61K2236/53A61K2800/5922A61K2300/00
Inventor 卓玛东智普珍袁瑞瑛李斌黄山
Owner TIBET UNIV
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