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Chinese medicinal composition for treating skin wounds and preparation method thereof

A skin wound and composition technology, applied in the field of traditional Chinese medicine composition, can solve problems such as allergies and inability to resist scars at the same time, and achieve the effect of promoting tissue regeneration, promoting skin wound healing, and good therapeutic effect

Inactive Publication Date: 2010-09-29
CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the existing traditional Chinese medicine preparations for the treatment of skin wounds, such as moist burn ointment, Kangfuxin drops, etc., although they have a good therapeutic effect on skin wounds, they also have some problems such as not being able to resist the formation of scars at the same time, or producing Allergies and other deficiencies

Method used

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  • Chinese medicinal composition for treating skin wounds and preparation method thereof
  • Chinese medicinal composition for treating skin wounds and preparation method thereof
  • Chinese medicinal composition for treating skin wounds and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1 Prepare the microemulsion preparation of Chinese medicine composition of the present invention

[0020] Dry 1000g of Periplaneta americana and 1000g of Centella asiatica as raw materials of traditional Chinese medicine at 50°C in vacuum, grind them separately and mix well, add 85% ethanol with an amount 14 times the total weight of the raw materials, soak at room temperature for 24 hours, filter, and repeat 3 times, combine the filtrate and recover to a viscous syrupy extract; dissolve in distilled water at 20°C-60°C that is twice the weight of the raw material of the cockroach body, stir to make it fully dissolved, and then let it stand for stratification to remove the insoluble matter in the upper layer After filtering the lower aqueous solution, the resulting filtrate was concentrated under reduced pressure to obtain 2000ml of mixed water-soluble extract 1, and every ml of mixed water-soluble extract 1 was equivalent to 1g of the raw material.

[0021] Dr...

Embodiment 2

[0036] Example 2 Prepare the ointment preparation of Chinese medicine composition of the present invention

[0037] Dry 1,000g of Periplaneta americana and 5,000g of Centella asiatica as raw materials for traditional Chinese medicine at 50°C in vacuum, pulverize them and mix them evenly, add 85% ethanol with an amount 14 times the total weight of the raw materials, soak at room temperature for 24 hours, filter, and repeat 3 times, the filtrate was combined and recovered to a viscous syrupy extract, dissolved in 50°C physiological saline that was 1 times the weight of the raw material, stirred to fully dissolve, left to separate layers, and the lower aqueous solution was separated, filtered, and the filtrate reduced Concentrate under pressure to obtain 3000ml of mixed water-soluble extract 1, and each ml of mixed water-soluble extract 1 is equivalent to 2g of raw materials.

[0038] Dry 1000 g of the raw material Glycyrrhiza inflata at 50°C in vacuum, crush it, add 12 times t...

Embodiment 3

[0054] Example 3 Another ointment preparation of the Chinese medicine composition of the present invention

[0055] Dry 5000g of Periplaneta americana and 1000g of Centella Asiatica as raw materials of traditional Chinese medicine at 50°C in vacuum, pulverize them and mix them evenly, add 85% ethanol with a volume concentration of 14 times the total weight of the raw materials, soak at room temperature for 24 hours, filter, and repeat 3 times, the filtrate was combined and recovered to a viscous syrupy extract, dissolved in 50°C physiological saline 0.5 times the weight of the raw material, stirred to fully dissolve, left to separate layers, and the lower aqueous solution was separated, filtered, and the filtrate was reduced. Concentrate under pressure to obtain 3000ml of mixed water-soluble extract 1, and each ml of mixed water-soluble extract 1 is equivalent to 2g of raw materials.

[0056] 1000 g of the raw material licorice inflata was vacuum-dried at 50°C, crushed, adde...

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Abstract

The invention discloses a Chinese medicinal composition for treating skin wounds and a preparation method thereof. The Chinese medicinal composition is prepared from 1 to 5 weight parts of cockroach, 1 to 5 weight parts of asiatic pennywort herb, 1 to 5 weight parts of liquoric root and 1 to 5 weight parts of Sinkiang arnebia root which serve as active ingredients. The method comprises the following steps of: performing ethamol extraction on the raw materials such as the cockroach and the asiatic pennywort herb in a weight ratio to obtain mixed water-soluble extractum 1, wherein the concentration of the mixed water-soluble extractum 1 is equal to 0.5 to 2.5g of crude medicaments every ml; soaking the liquoric root with ammonia water, concentrating and drying the liquoric root under the reduced pressure to obtain a dry extractum 2; performing ethamol extraction on the Sinkiang arnebia root in ratio amount, concentrating filtrate to obtain dry extractum, extracting the dry extractum with petroleum ether, and concentrating the dry extractum until forming dry extractum 3; and adding the mixed water-soluble extractum 1, the dry extractum 2 and the dry extractum 3 into a matrix and auxiliary materials needed by various external formulations, and preparing the mixture to obtain the Chinese medicinal external preparation for treating the skin wound. The Chinese medicinal composition can be used for the skin wound caused by various physical factors or chemical factors, has obvious curative effect. Animal experiments prove that the Chinese medicinal composition can promote the skin wound to quickly heal, can inhibit scars after wound healing, and has the effective rate of over 95 percent.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating skin wounds. Background technique [0002] The normal skin of the body is damaged and invaded by external physical, chemical, microbial and other factors. If the dermis is damaged, skin scar tissue is often produced, and the physiological structure of the skin is difficult to recover, which seriously affects the function and appearance of the skin. The mentality caused great distress, which in turn led to a lack of confidence in life and work, especially in the field of burn surgery, this problem is more prominent. [0003] In the existing traditional Chinese medicine preparations for the treatment of skin wounds, such as moist burn ointment, Kangfuxin drops, etc., although they have a good therapeutic effect on skin wounds, they also have some problems such as not being able to resist the formation of scars at t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/107A61K9/06A61P17/02A61K35/64
Inventor 李劲平宋香清张杰陈腊梅
Owner CENT SOUTH UNIV
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