Method for producing 225actinium from 226radium

A ph value and solution technology, which is applied in the direction of radiation conversion of chemical elements, external conversion of reactors/accelerators, recovery of specific isotopes, etc., can solve problems such as long irradiation time and loss

Pending Publication Date: 2021-12-31
ДЗЕ ЮРОПИЕН ЮНИОН, РЕПРИЗЕНТЕД БАЙ ДЗЕ ЮРОПИЕН КОММИШН
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Problems solved by technology

The disadvantage of such a long irradiation time is that, 225 Ac has decayed after being produced, making the produced 225 Ac loses a considerable portion of its production

Method used

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  • Method for producing 225actinium from 226radium
  • Method for producing 225actinium from 226radium

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[0102] Table 2: Available for figure 2 Examples of the composition of the extraction apparatus and solutions in the high acidity plant shown.

[0103] Target solution 0.5M HNO 3 and 0.35M 226 Ra(NO 3 ) 2

The first extraction device 6 DGA (Eichrome, TODGA) rinse solution 8 0.5M HNO 3

Radium extraction device 10 SCE (DOWEX 50W) Radium eluent 12 2M HNO 3

First eluent 16 0.05M HNO 3

Second extraction device 18 Ln resin (Eichrome, HDEHEP) Second eluent 19 0.5M HNO 3

The third extraction device 22 DGA (Eichrome, TODGA) third eluent 24 0.1M HNO 3

Lead Extraction Unit 30 Sr resin (Eichrome)

[0104] It can be seen that the concentrated and purified 225 Ac has been removed from the third extraction unit 22 . However, in the fifth closed circuit 21 an additional extraction column, namely a lead extraction unit 30 , is provided between the second extraction unit 18 and th...

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Abstract

225actinium is produced from 226radium by irradiating a liquid 226radium target by means of protons, deuterons or gamma irradiation in an irradiation device (2) and by extracting the produced 225actinium out of the irradiated liquid target solution in a first extraction device (6). The liquid target solution from which the 225actinium has been removed is then irradiated again to produce further 225actinium therein. The liquid target solution is preferably circulated, in a closed loop (4), over the irradiation device and in a further closed loop (7) over the first extraction device (6). An advantage of such a method is that the irradiated target solution does not need to be dried and re-dissolved to be able to separate the produced actinium from the radium and no further drying and re-dissolving step is needed for producing the liquid target again starting from the separated radium. The radium target can thus be recycled in a more efficient and safer way, especially in view of the radon gas which is continuously produced by the decay of 226radium.

Description

technical field [0001] The present invention relates to a 226 radium production 225 Actinium method, wherein, providing 226 A liquid target solution of radium, wherein said liquid target solution is irradiated in an irradiation device to extract from the 226 Radium starts to be produced in liquid target solution 225 actinium; and at least part of the resulting 225 Actinium and the remainder 226 Ra separates. Background technique [0002] 225 Actinium is an interesting radionuclide that can be used in cancer therapy. 225 Actinium is a radioactive isotope that emits alpha rays with a half-life of 10 days. It can be used as a reagent in radioimmunotherapy. Alpha particle emitters are promising radiation sources for lethal irradiation of single cancer cells and micrometastases due to their intensive ionizing radiation. Alpha particles are advantageous for radioimmunotherapy applications because their range in soft tissues is limited to a few cell diameters. [0003] T...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G21G1/00
CPCG21G1/001G21G2001/0089G21G1/10G21G1/12
Inventor 里卡德·马姆贝克罗伯托·卡奇乌夫尼度·拉尔·巴尼克
Owner ДЗЕ ЮРОПИЕН ЮНИОН, РЕПРИЗЕНТЕД БАЙ ДЗЕ ЮРОПИЕН КОММИШН
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