Method and device for calculating fractional flow reserve based on vascular intravascular image, calculation equipment and storage medium

Abstract

The invention discloses a method and a device for calculating fractional flow reserve based on a vascular intracavity image, computing equipment and a storage medium. The method comprises the following steps: acquiring an image sequence for performing vascular intracavity image division; performing coarse and fine segmentation on the image sequence to determine a blood vessel cavity boundary; mapping the determined vascular lumen boundary to an axial image generated based on the image sequence; screening a suspected bifurcation point sequence by analyzing a boundary strength value in a neighborhood range of each vascular cavity boundary point in the axial graph; after the suspected bifurcation point sequence is mapped to each frame of original image, determining a fan-shaped region formed by an arc line formed by the suspected bifurcation point sequence and a catheter central point, determining a catheter artifact according to the similarity of the fan-shaped region on the image sequence, and deleting a bifurcation point corresponding to the catheter artifact in the suspected bifurcation points to obtain the determined bifurcation point; after bifurcated blood vessels are determined according to the determined bifurcated points, constructing a blood vessel model by combining the main blood vessel and the bifurcated blood vessels determined according to the boundary of the blood vessel cavity; and calculating FFR according to the blood vessel model.

Description

technical field [0001] The invention belongs to the field of medical image processing, and in particular relates to a method, a device, a computing device and a storage medium for calculating a blood flow reserve fraction based on an intravascular image. Background technique [0002] In today's clinical practice, coronary artery disease is mostly diagnosed using invasive imaging modalities, of which coronary angiography is the most popular and is currently considered the gold standard for cardiac catheterization and hemodynamic assessment. However, photometric maps produced by coronary angiography only depict the two-dimensional projected diameter of the lumen at a specific projection angle without any geometrical information about the lumen or plaque. Therefore, recent coronary angiography is often accompanied by newer intravascular imaging techniques such as intravascular ultrasound (Intravascular UltraSound, IVUS) and optical coherence tomography (Optical Coherence Tomogr...

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Problems solved by technology

[0004] Although OCT images and IVUS images can effectively obtain information on vascular stenosis, IVUS and OCT do not have the function of measuring coronary artery fractional flow reserve (Fractional Flow Reserve, FFR), and cannot judge whether there is functional stenosis in coronary vessels

If the blood flow reserve fraction of the coronary vessels needs to be measured, an invasive pressure guide wire is required, and at the same time, the coronary artery is under the condition of maximum hyperemia induced by intravenous administration of adenosine, which not only increases the complexity of the operation sexuality, and also poses increased risk and cost to the patient

[0005] The patent application with the publication number CN107977965A discloses a non-invasive calculation method for FFR of superior mesenteric artery dissection based on CT images, and the patent application with the publication number CN106650029A discloses a fast calculation of the bifurcation blood vessel pressure difference and FFR based on CFD simulation Methods and systems, both of which are non-invasive methods for measuring coronary FFR, but neither is based on intravascular imaging

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