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System for predicting severe acute pancreatitis and application thereof

A technology for acute pancreatitis and severe disease, which is applied in the field of biomedicine and can solve problems such as complicated use

Pending Publication Date: 2022-01-07
PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above methods rely on imaging examinations, which are more complicated to use in practice, and emergency physicians need a scoring standard that does not rely on imaging examinations

Method used

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  • System for predicting severe acute pancreatitis and application thereof
  • System for predicting severe acute pancreatitis and application thereof
  • System for predicting severe acute pancreatitis and application thereof

Examples

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Embodiment 1

[0078] Embodiment 1, the development and verification of the model

[0079] Subject information

[0080] The present invention is a multi-center retrospective study. Patients diagnosed with AP from different regions in China (Peking Union Medical College Hospital, Beijing Sixth Hospital, Fourth Affiliated Hospital of Harbin Medical University, West China Longquan Hospital of Sichuan University) from January 1, 2017 to December 31, 2019 were collected for development. Cohort participation in building clinical predictive models. The independent external validation cohort consisted of patients with AP who attended Peking Union Medical College Hospital between January 1, 2020, and May 31, 2021.

[0081] AP is diagnosed if at least two of the following three criteria are met: abdominal pain consistent with acute pancreatitis, serum amylase and / or lipase elevated to more than three times the upper limit of the normal range, and computed tomography (CT), magnetic resonance imaging...

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Abstract

The invention belongs to the field of biomedicine, and particularly relates to a system for predicting severe acute pancreatitis and application thereof. The system comprises a calculation device for calculating the illness risk according to the heart rate, the respiratory rate, the serum calcium concentration and the blood urea nitrogen. Meanwhile, the invention also provides application of the system in preparation of a product for calculating the risk of severe acute pancreatitis.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to a system for predicting severe acute pancreatitis and its application. Background technique [0002] Acute pancreatitis (AP) is an inflammatory reaction in which pancreatic tissue is digested, edema, hemorrhage, and even necrosis after activation of pancreatic enzymes due to various etiologies. Clinically, it is characterized by acute epigastric pain, nausea, vomiting, fever, and increased pancreatic enzymes. Acute pancreatitis is a common emergency of the digestive system, and most patients are diagnosed as mild acute pancreatitis (MAP) or moderate severe acute pancreatitis (Moderate severe acute pancreatitis, MSAP). 10-20% of patients develop severe acute pancreatitis (Severe Acute Pancreatitis, SAP) due to critical condition and persistent organ failure. Severe acute pancreatitis is acute pancreatitis accompanied by serious systemic and local complications. In the 19...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/20G16H50/70A61B5/0205
CPCG16H50/20G16H50/70A61B5/0205
Inventor 吴东李云龙李佳宁施文陈国榕宋锴范正阳韩梓莹闫夏晓杨子涵
Owner PEKING UNION MEDICAL COLLEGE HOSPITAL CHINESE ACAD OF MEDICAL SCI
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