Method for qualitatively screening and confirming 25 additives in Chinese patent medicine and health-care oral liquid
A technology of health care products and additives, applied in the field of drug analysis, can solve the problems of false positive, complex matrix, false negative, etc., and achieve the effect of good reproducibility and high sensitivity
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[0022] Example embodiments described below with reference to the specific substance of the present invention, but are not meant to limit the scope of the present invention.
[0023] First, the instruments and reagents
[0024] Liquid LC-20AD-8050 mass spectrometer; XS205DC Mettler analytical balance.
[0025] Sodium saccharin (dihydrate) (Lot: ST107701-869, Purity: 100.0%), aspartame (Lot: STC63701-9575, purity: 99.4%), neotame (Lot: ST54980120-5529, purity: 99.5%) alitame (batch number: STC67401-9780, purity: 100.0%), acesulfame-K (aka: acesulfame K, batch number: STC63801-9574, purity: 100.0%), cyclamate (batch number: ST219401-9573, purity: 100.0%), ethyl maltol (lot: 9774, purity: 100%) were purchased from Nature Standard; Sudan I (lot: 111953-201301, purity: \), Sudan IV (lot: 111950-201602, purity : \), scarlet 808 (batch number: 111940-201804, purity: \), new Fuchsin (lot: 111955-201301, purity: \), auramine O (lot: 111770-201603, purity: \), stevioside ( lot: 111515-201803...
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Abstract
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