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Liquid-phase chip detection system and method for analyzing one or more to-be-analyzed subjects

A liquid phase chip detection and detection system technology, which is applied in the direction of analyzing materials, material excitation analysis, chemical instruments and methods, etc., can solve the problems of detection sensitivity and accuracy to be improved, and achieve the effect of improving accuracy

Pending Publication Date: 2022-01-28
深圳市液芯科技有限公司
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Problems solved by technology

As a new type of biomolecular detection technology, liquid phase suspension chip technology has significant advantages such as high throughput, fast speed and low cost for biomolecular detection, but its detection sensitivity and accuracy still need to be improved

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  • Liquid-phase chip detection system and method for analyzing one or more to-be-analyzed subjects
  • Liquid-phase chip detection system and method for analyzing one or more to-be-analyzed subjects
  • Liquid-phase chip detection system and method for analyzing one or more to-be-analyzed subjects

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Embodiment Construction

[0039] The present invention will be further described in detail below through specific embodiments in conjunction with the accompanying drawings.

[0040] The liquid phase chip detection system provided by the present invention can analyze (detect) one or more analytes, and is suitable for various detection equipment, such as liquid phase chip detectors, which can be used for in vitro diagnosis and immune analysis from a functional point of view , molecular diagnosis, etc.

[0041] Such as figure 1 and figure 2 As shown, the detection system includes: a detection area 11 , a processing device 20 , a detection device 30 , a light source 40 and an electrode 50 . The detection device 30 , the light source 40 and the electrodes 50 are all electrically connected to the processing device 20 .

[0042] The detection area 11 is used to provide a detection site for one or more particles f to be analyzed. The particles to be analyzed are arranged in a single layer in the detection...

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Abstract

The invention provides a liquid-phase chip detection system and a method for analyzing one or more to-be-analyzed subjects. An electric field is applied to the to-be-analyzed particles in a detection area through the electrodes, so that the to-be-analyzed particles are subjected to electrochemical luminescence reaction, and report light signals related to the to-be-analyzed subjects combined on the to-be-analyzed particles are emitted; and a detection device detects the report optical signal to obtain report optical signal data, and the processing device processes the report optical signal data to obtain the content of the to-be-analyzed subjects. Due to the adoption of the electrochemical luminescence reaction, an excitation light source is not needed when the report light signal is detected, so that background noise of the light source is avoided, the detection sensitivity and accuracy of the report light signal are improved, and the detection sensitivity and accuracy of the to-be-analyzed subjects are also improved.

Description

technical field [0001] The invention relates to the technical field of biochip detection, in particular to a liquid phase chip detection system and a method for analyzing one or more analytes. Background technique [0002] Liquid phase suspension chip technology is a cutting-edge molecular detection technology integrating fluid technology, particle synthesis technology, molecular hybridization technology, and high-efficiency digital signal processing technology. Its principle is to combine known molecules (DNA, RNA, polypeptide, protein, small molecule etc.) integrated on the surface of one or more microparticles to form a probe array, capture one or more analytes in the sample, and couple the analytes to one or more luminescent substances (fluorescent dyes, fluorophores or Fluorescent particles, Raman spectrum characteristic molecules, etc.) are used as labels, and then the luminescent objects are excited by an excitation light source to emit light, and then detected by opt...

Claims

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Application Information

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IPC IPC(8): G01N21/64G01N21/76G01N21/01B01L3/00
CPCG01N21/6486G01N21/763G01N21/01B01L3/00G01N2021/0112
Inventor 王东风张健刘军营
Owner 深圳市液芯科技有限公司
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