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Human body efficacy quantitative evaluation method for blue light protection and application of human body efficacy quantitative evaluation method

A quantitative evaluation, blue light technology, applied in the field of technical cosmetics skin science, can solve the problems of lack of blue light protection efficacy evaluation methods, and achieve the effect of intuitive evaluation methods

Pending Publication Date: 2022-03-08
马彦云 +5
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a quantitative evaluation method for human body efficacy of blue light protection to solve the technical problem of lack of blue light protection efficacy evaluation method

Method used

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  • Human body efficacy quantitative evaluation method for blue light protection and application of human body efficacy quantitative evaluation method
  • Human body efficacy quantitative evaluation method for blue light protection and application of human body efficacy quantitative evaluation method
  • Human body efficacy quantitative evaluation method for blue light protection and application of human body efficacy quantitative evaluation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] This embodiment provides a quantitative evaluation method for human body efficacy of blue light protection.

[0085] The blue light source is: the relative proportion of 400-700nm is not less than 50%, and the wavelength band less than 400nm is not higher than 2.5%.

[0086] Test samples (that is, protective samples): Sample 1 is the company's product protective cream (from the self-made sample of Shanghai Fudun Testing Technology Co., Ltd.).

[0087] The tester meets the following requirements:

[0088] (1) The number of testers is 35;

[0089] (2) Choose healthy volunteers aged 18 to 60, both male and female;

[0090] (3) No history of light-sensitive diseases in the past, and no drugs that affect light-sensitivity within 6 months before the test;

[0091] (4) The tester's skin type is above type III, among which there are no less than 5 people with type III and IV skin;

[0092] (5) The skin at the test site should be free from pigmentation, inflammation, scars, ...

Embodiment 2

[0110] In this embodiment, the tester is tested by the method of Example 1, and the specific data obtained are shown in Table 1.

[0111] Detector: data number F024, gender: male; age: 58 years old; skin type: III.

[0112] Table 1: Distribution of Delta M value of tester F024 at 5 time points between the uncoated sample group and the coated sample group

[0113]

[0114]

[0115] In Table 1, M is the melanin index; Delta M is the M difference between the test area and the standard area or the M difference between the control area and the standard area, indicating the change in the melanin index M.

[0116] Take Delta M as the Y axis and the number of days as the X axis to draw a graph, such as figure 1 As shown, and the slope is calculated by the calculation formula in Example 1, the slope K1 of the control area, that is, the unsmeared sample group, is 2.18; the slope of the test area, that is, the smeared sample group, is K2, which is 2.01. Calculate BPF = 2.18 / 2.01 ...

Embodiment 3

[0130] For sample 1 in Example 1, 35 testers (F001~F036, wherein the data of F027 was lost to follow-up) were tested, the data are shown in Table 5, the statistical description of the delta value of the product group and the control group every day, Table 5 includes Table 5.1, Table 5.2 and Table 5.3.

[0131] Table 5.1

[0132]

[0133]

[0134] Table 5.2

[0135]

[0136] Table 5.3

[0137]

[0138]

[0139] Fit the linear equation to the mean value and time in Table 5, and calculate the slope and BPF. The results are shown in Table 6. Table 6 shows the slope and BPF of the product group and the control group at the levels of delta M, delta L and delta ITA° .

[0140] Table 6

[0141] K Product control BPF Delta M 0.63 1.12 1.77 Delta L -0.67 -1.19 1.77 Delta ITA° -1.77 -2.43 1.37

[0142] In summary, the method of the present invention can effectively detect the blue light protection index of the protection samp...

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Abstract

The invention provides a human body efficacy quantitative evaluation method for blue light protection and application. The blue light protection human body efficacy quantitative evaluation method comprises the following steps: setting a test area, a contrast area and a standard area on to-be-tested skin, and measuring melanin indexes, brightness indexes and skin yellow staining indexes of the areas; coating a blue light protection sample in the test area; performing blue light irradiation on the test area and the control area, and respectively measuring melanin indexes, brightness indexes and skin yellow staining indexes of the skin in the test area, the control area and the standard area; and calculating the blue light protection index. The invention provides the quantitative evaluation method for the human body efficacy of blue light protection, the deficiency of a blue light protection efficacy evaluation method is made up, a more intuitive evaluation method is provided for a blue light protection sample, and the method has important significance for research and development of the blue light protection sample.

Description

technical field [0001] The invention relates to the field of technical cosmetics and dermatology, in particular to a quantitative evaluation method for human body efficacy of blue light protection and its application. Background technique [0002] Blue light is visible light that is ubiquitous in daily life, and its wavelength is 400-500nm, which belongs to high-energy visible light. The impact of blue light on the human body is multifaceted, it can cause damage to the human visual system and affect the biological rhythm of the human body. Studies have shown that high-energy blue light can cause serious damage to human skin, causing macula, freckles, accelerating skin aging, causing skin allergies, and affecting sleep quality. Blue light exposure can cause obvious skin pigmentation in dark-skinned people, while it has a slight effect on light-skinned people, especially seriously affecting the skin pigmentation of Chinese people. In today's society, there are more and more ...

Claims

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Application Information

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IPC IPC(8): A61B5/00G06F17/11
CPCA61B5/443G06F17/11
Inventor 马彦云濮伟霖张蕊王久存刘玮谈益妹
Owner 马彦云
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