Stress bioreactor for tissue and organ culture and culture robot

Abstract

The invention relates to a stress bioreactor for tissue and organ culture and a culture robot, and is characterized in that the stress bioreactor comprises a driving device (1) and a plurality of culture chambers (9) arranged in parallel, a movable clamp (7) and a fixed clamp (8) are arranged in each culture chamber (9), and two ends of an artificial tissue or organ (10) are clamped between the movable clamp (7) and the fixed clamp (8); a driving device (1) is connected with the movable clamp (7) in each culture room (9) through a transmission mechanism, so that the artificial tissues or organs (10) clamped by the movable clamps (7) are driven to do reciprocating stretching motion. The multi-culture-room parallel design is adopted, a plurality of artificial tissues or organs can be cultured independently at the same time and do not interfere with one another, and the machine use efficiency and the artificial tissue or organ culture efficiency are greatly improved. And more culture rooms can be further expanded by lengthening the cross beam and modularly splicing the base.

Description

technical field [0001] The invention relates to a biological tissue engineering culture device, in particular to a stress bioreactor for tissue and organ culture, a tissue and organ culture robot and a control method thereof. Background technique [0002] At present, artificial tissues or organs constructed by tissue engineering methods have the bottleneck of insufficient mechanical properties and biological functions, which restricts the clinical application of artificial tissues or organs. One of the important reasons for this phenomenon is the lack of mechanical stimulation in the process of artificial tissue or organ culture in vitro. Therefore, bioreactor devices that can provide tissue-specific mechanical stimuli when artificial tissues or organs are cultured in vitro are particularly important. [0003] Most of the devices in the prior art adopt the design of one driving device corresponding to one culture chamber, but when culturing tissues and organs, it is often n...

AI Technical Summary

Problems solved by technology

[0006] The present invention designs a stress bioreactor and a culture robot for tissue and organ culture, and the technical problems it solves are: (1) the prior art cannot realize the simultaneous cultivation of multiple culture chambers by one drive device; (2) The cultivation chamber and the driving device are not easy to disassemble; (3) The cultivation chamber of the prior art has poor sealing effect, and bacterial contamination is prone to occur

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