Characteristic substance concentration, extraction and separation device for supervision and analysis of market medicine finished products

Abstract

The invention discloses a characteristic substance concentration, extraction and separation device for market drug finished product supervision and analysis, the device comprises a crushing assembly, a dissolution and extraction assembly, a concentration and separation assembly and an outer frame, the crushing assembly is mounted on a first-layer partition plate, the dissolution and extraction assembly is mounted on a second-layer partition plate, the concentration and separation assembly is mounted on the bottom side in the outer frame, and the outer frame is mounted on the outer frame. The dissolving and extracting assembly is located under the smashing assembly, and the concentrating and separating assembly is located under the dissolving and extracting assembly. The smashing assembly can cause mutual collision between large and small medicine fragments through annular airflow, tablets are further smashed into smaller particles, the dissolving and extracting assembly is driven by the spraying force of carbon tetrachloride to rotate, the dissolving speed of the medicine particles is increased, and the medicine particles can be effectively dissolved. And the carbon tetrachloride solution can be in full contact with the aqueous solution, so that the phenomenon of insufficient extraction is avoided.

Description

technical field [0001] The invention relates to the technical field of drug extraction and separation, in particular to a characteristic substance concentration, extraction and separation device used for regulatory analysis of finished drug products in the market. Background technique [0002] Drugs are indispensable items in people's lives. They are related to our life, health and safety, and directly affect our quality of life. Many drugs containing molecular iodine are used for sterilization and anti-infection, and the effective iodine concentration is directly related to the anti-infection effect of the drug, and excessive iodine intake may lead to excessive hyperplasia of the thyroid gland, so the molecular iodine content of the characteristic The determination of is the top priority of the supervision of iodine-containing drugs. However, the conventional iodine content detection is mostly carried out by semi-manual and semi-mechanical methods, and the accuracy of this...

AI Technical Summary

Problems solved by technology

However, the conventional iodine content detection is mostly carried out by semi-manual and semi-mechanical methods, and the accuracy of this detection method is often not guaranteed.

Most of the traditional concentration, extraction and separation equipment do not have a device for crushing tablets, and some devices with a crushing function cannot guarantee the degree of crushing, and often the drug powder remains in the crushing device

On the other hand, most of the traditional extraction devices rely on shaking and vibration to help the contact between the extractant and the solvent. This extraction method often cannot completely extract the characteristic substances. Some equipment will use rapid stirring to assist the extraction, but the elemental iodine Due to its easy sublimation physical characteristics, elemental iodine is often lost due to local overheating in the process of rapid stirring

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