Application of 4, 4-diisothiocyano stilbene-2, 2-disulfonic acid in preparation of medicine for preventing and/or treating obesity

A technology of isothiocyanate and disulfonic acid, applied in medicine, the field of anion transport inhibitor 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid
CN114288282AActive Publication Date: 2022-04-08庹必光
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
庹必光
Publication Date
2022-04-08

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Abstract

The invention relates to an application of an anion transport inhibitor 4, 4 '-diisothiocyanatostilbene-2, 2'-disulfonic acid in preparation of medicines for preventing and / or treating obesity, and belongs to the technical field of new applications of medicines. The anion transport inhibitor 4, 4 '-diisothiocyano stilbene-2, 2'-disulfonic acid can be applied to preparation of drugs for effectively treating obesity, obesity caused by high-fat diet is effectively relieved, weight is reduced, accumulation of visceral fat, scapular fat and epididymis fat is reduced, and abnormal glucose metabolism caused by obesity is effectively relieved. The application of the anion transport inhibitor 4, 4 '-diisothiocyano stilbene-2, 2'-disulfonic acid in preparation of the medicine for treating obesity is disclosed for the first time, and the anion transport inhibitor 4, 4 '-diisothiocyano stilbene-2, 2'-disulfonic acid has an unexpected effect in the aspect of inhibiting obesity.
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Description

technical field

[0001] The invention relates to the technical field of new uses of medicines, in particular to anion transport inhibitor 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid , DIDS) in the preparation of medicaments for the prevention and / or treatment of obesity. Background technique

[0002] Obesity refers to excessive accumulation and (or) abnormal distribution of fat in the body leading to weight gain. It is a chronic metabolic disease caused by the interaction of multiple factors including genetic and environmental factors. Overweight and obesity, especially abdominal obesity, have a variety of metabolic abnormalities, which are important risk factors for cardiovascular and cerebrovascular diseases, diabetes, certain cancers and some other chronic diseases.

[0003] In recent years, with the changes in diet structure and lifestyle, the incidence of obesity in my country has increased significantly. Obesi...

Claims

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