Unlock instant, AI-driven research and patent intelligence for your innovation.

Process for continuously producing isopropanolamine

A propylene oxide and loop reactor technology, applied in the field of continuous process, can solve the problems of improper control of propylene oxide concentration, poor selectivity of monoisopropanolamine, easy occurrence of temperature flying, etc. Eliminate the effects of many side reactions and long service life

Pending Publication Date: 2022-04-12
WANHUA CHEM GRP CO LTD
View PDF12 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The present invention aims to solve the problems of harsh conditions, low product yield, poor selectivity of monoisopropanolamine and many by-products in the isopropanolamine production method using water as a catalyst in the prior art. Improper control of the oxypropane concentration leads to the problem that the reaction is prone to runaway temperature. A method for preparing isopropanolamine using a solid-supported heteropolyacid as a catalyst and using a loop reactor to catalyze amination and continuous production is provided.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Process for continuously producing isopropanolamine
  • Process for continuously producing isopropanolamine
  • Process for continuously producing isopropanolamine

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0056] Preparation of immobilized heteropolyacid catalyst:

[0057] 1. Experimental raw materials

[0058] Phosphotungstic acid (H 3 [P(W 3 o 10 ) 4 ]·12H 2 O), silicotungstic acid (H 3 [Si(W 3 o 10 ) 4 ]·12H 2 O), phosphomolybdic acid (H 3 [P(Mo 3 o 10 ) 4 ]·12H 2 O): analytically pure, Sigma-Aldrich (Shanghai) Trading Co., Ltd.,

[0059] Bentonite, MCM-41, methanol: analytically pure, Sinopharm Chemical Reagent Co., Ltd.

[0060] 2. Preparation example

preparation example 1

[0062] Catalyst A: Immobilized phosphotungstic acid catalyst

[0063] Add 1.5g of phosphotungstic acid and 12.55g of bentonite into a three-necked flask, then add 70ml of methanol to dissolve completely, and stir at room temperature for 5h. After that, the solvent was removed under reduced pressure, and the product was dried in a vacuum oven at 110°C for 6 hours. After drying, it was roasted in a muffle furnace at 300°C for 8 hours to prepare a solid-supported heteropolyacid with a loading capacity of phosphotungstic acid of about 10%. catalyst. By adjusting the amount of phosphotungstic acid and bentonite, it is possible to prepare immobilized phosphotungstic acid catalysts with loadings of 20%, 30%, 40%, 50%, and 60%.

preparation example 2

[0065] Catalyst B: Immobilized phosphomolybdic acid catalyst

[0066] Add 1.5g of phosphomolybdic acid and 3.13g of MCM-41 into a three-necked flask, then add 30ml of methanol to dissolve completely, and stir at room temperature for 5h. Afterwards, the solvent was removed under reduced pressure, and the product was dried in a vacuum oven at 120°C for 4 hours. After drying, it was activated in a muffle furnace at 250°C for 10 hours to prepare a solid-supported heteropolyacid with a loading capacity of phosphomolybdic acid of about 30%. catalyst. By adjusting the amount of phosphomolybdic acid and MCM-41, the immobilized phosphomolybdic acid catalysts with loadings of 10%, 20%, 40%, 50% and 60% can be prepared.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a process for continuously producing isopropanolamine by using a loop reaction system, which adopts an immobilized heteropolyacid catalyst and takes epoxypropane and liquid ammonia as raw materials. The immobilized heteropolyacid catalyst is used for isopropanolamine production through a loop reactor continuous production system, and by means of good mixing of the loop reactor, the disadvantage that the local concentration of epoxypropane is too high is eliminated, meanwhile, the immobilized heteropolyacid catalyst can be in full contact with reaction liquid, and the yield of isopropanolamine is increased. The catalytic effect of the supported heteropolyacid catalyst is greatly exerted, and the selectivity to monoisopropanolamine is remarkable and can reach 95% or above.

Description

technical field [0001] The invention belongs to the field of isopropanolamine production, and more specifically relates to a continuous process for efficiently synthesizing isopropanolamine by using a solid-supported heteropolyacid as a catalyst and using a loop reactor. Background technique [0002] Monoisopropanolamine (MIPA), also known as 1-amino-2-propanol, is a colorless viscous liquid at room temperature, easily soluble in water and ethanol, and its aqueous solution is alkaline. Monoisopropanolamine has a wide range of applications: it can be used as industrial synthetic detergent, foam stabilizer, shampoo and surfactant in the detergent industry; it can be used as antistatic agent, refining agent, Fiber wetting agent and antioxidant, etc.; in the pharmaceutical intermediate industry, piperazine, morpholine, antibiotics such as procaine, penicillin G and diphenhydramine hydrochloride can be synthesized; in the metal processing industry, it can be used as metal cutting...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C213/04C07C213/10C07C215/08C07C215/12B01J29/03B01J29/04B01J35/10B01J27/188B01J31/18B01J8/18B01J19/00B01F25/312B01F23/40B01F23/45
Inventor 曹彦锴张聪颖李昱学刘富强杨晓坤王宁宁刘德彪丁皓
Owner WANHUA CHEM GRP CO LTD