Excrement sample P53 gene mutation kit

Abstract

The invention discloses a fecal sample P53 gene mutation kit, which is used for P53 mutation detection and beta-actin internal reference, comprises a Lina core nucleic acid extraction kit and peptide nucleic acid clamp (PNA) method detection, and comprises a kit body, a cotton cloth layer is arranged outside the kit body, and a rotatable detachable filter screen layer is arranged on the side surface of the kit body, which is positioned in the cotton cloth layer. A mounting frame is mounted outside the filter screen layer, an activated carbon layer for removing peculiar smell is mounted in an inner cavity of the mounting frame, an antibacterial layer is arranged on the side face of the activated carbon layer, a reinforcing ring is arranged on the side face of the antibacterial layer, the outer portion of the reinforcing ring is arranged in the middle of the inner cavity of the mounting frame, and an isolation filter layer is arranged on the side face of the reinforcing ring. The kit has the advantages that the detection diversity, specificity and accuracy are high, air entering from the outside of the kit can be filtered, germs and peculiar smells contained in the outside air can be eliminated, pressure can be effectively resisted, and damage caused by deformation of the kit body is avoided.

Description

technical field [0001] The invention relates to a P53 gene mutation kit, in particular to a stool sample P53 gene mutation kit. Background technique [0002] The kit refers to the box used to contain chemical reagents such as chemical components, drug residues, and virus types, which are generally used by hospitals and pharmaceutical companies; p53 gene, a human tumor suppressor gene, encodes a protein with a molecular weight of 43.7KDa. However, because the protein band appeared at 53KDa indicated by Marker, it was named P53. Because the protein contains a large amount of proline, the electrophoresis speed is slowed down. The inactivation of p53 gene plays an important role in tumor formation, mdm2 mutation and P53 mutation do not coexist, p53 is an important anti-cancer gene, its wild type makes cancer cells apoptosis, thereby preventing canceration; it also has the function of helping cells to repair defective genes function, p53 mutations increase carcinogenesis. [0...

AI Technical Summary

Problems solved by technology

[0003] At present, the inside of the P53 gene mutation kit is easy to enter the outside air when it is in use. In this way, when the outside is turbid or the gas containing germs enters the inside of the kit, it will interfere with the detection equipment inside the kit, and in severe cases, it will also cause the detection equipment to be damaged. It cannot be used directly, and it will also interfere with the test results; at the same time, when the kit is used, it is easy to be squeezed by external force, which will lead to deformation and damage of the kit; single detection, low specificity and accuracy

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