Circulating blood cell dose accumulation algorithm based on hemodynamic model simulation
A hemodynamic and model simulation technology, applied in the field of circulating blood cell dose accumulation algorithm based on hemodynamic model simulation, can solve the problems of no concept and algorithm technology implantation and display, inability to receive blood dose, etc. Achieve real reliability, easy to achieve results
Pending Publication Date: 2022-05-13
ZHONGSHAN HOSPITAL FUDAN UNIV
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Problems solved by technology
The actual flowing blood system and the "resting" state CT images based on TPS calculations cause a pair of stark contradictions. The dose calculation of the TPS system cannot truly count the blood exposure dose in the systemic circulatory system at all.
In any of the current clinical TPS products, there is no implantation and display of this concept and algorithm technology
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[0020] Below according to the accompanying drawings figure 1 , give a preferred embodiment of the present invention, and give a detailed description, so that the functions and characteristics of the present invention can be better understood.
[0021] see figure 1 , a circulating blood cell dose accumulation algorithm based on a hemodynamic model simulation in an embodiment of the present invention, comprising steps:
[0022] S1: According to the CT positioning image, take a single blood vessel in the tumor radiotherapy area in the vascular system, set the blood flow velocity and cross-sectional area of the blood vessel, and establish a hemodynamic model of the blood vessel. The hemodynamic model includes multiple blood vessels. Stream parameters such as figure 1 shown;
[0023] S2: According to the radiotherapy planning parameters of the radiotherapy planning system, align the position of the hemodynamic model of the blood vessel to the radiotherapy field projection syst...
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The invention provides a circulating blood cell dose accumulation algorithm based on hemodynamic model simulation, and the algorithm comprises the steps: S1, building a blood vessel hemodynamic model according to a CT positioning image; s2, aligning the position of the hemodynamic model of the blood vessel to a radiotherapy radiation field projection system in a three-dimensional space; s3, analyzing the CT positioning image to obtain a dose projection system parameter; using a blood flow dose projection dynamic convolution model to count deposition dose in the blood vessel during dynamic blood radiotherapy; and S4, drawing a human blood cell metrology cumulative differential statistical chart according to the deposited dose. According to the circulating blood cell dose accumulation algorithm based on hemodynamic model simulation, a blood exposure dose calculation tool is provided, and statistics and calculation of the actual exposure dose of immune cells in blood are completed in a TPS system; and creating an irradiated cumulative dose statistical model of the flowing blood cells of the patient in clinical radiotherapy.
Description
technical field [0001] The invention relates to the field of circulating blood cell dose accumulation algorithms, in particular to a circulating blood cell dose accumulation algorithm based on hemodynamic model simulation. Background technique [0002] China is a country with a large population, and cancer is one of the three major diseases that cause human death. The traditional main treatment methods for malignant tumors include surgery, radiotherapy, and chemotherapy, and about 60%-70% of tumor patients need radiotherapy. In recent years, with the development of clinical oncology, medical imaging, radiation physics, radiation biology and tumor immunology, radiation therapy technology has undergone a change from two-dimensional irradiation technology to three-dimensional irradiation technology. From two-dimensional general radiation technology (2D-CRT) to three-dimensional conformal radiation technology (3D-CRT), and then from intensity modulated technology (IMRT) to volu...
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Login to View More IPC IPC(8): G16H50/50G16H20/40G16H30/20G06T7/00G06T7/62A61N5/10
CPCG16H50/50G16H20/40G16H30/20G06T7/0012G06T7/62A61N5/1031G06T2207/10081G06T2207/30104G06T2207/30096
Inventor 杜世锁周永康曾昭冲
Owner ZHONGSHAN HOSPITAL FUDAN UNIV