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Particle sorting method based on acoustic artificial structure

An artificial structure and particle technology, applied in chemical instruments and methods, classification, solid separation, etc., can solve the problems of not being too wide, flux limitation, channel not too high, etc., to achieve low production cost, wide channel, and processing throughput high effect

Active Publication Date: 2022-05-27
SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method has high precision and is easy to observe, but because it is sorted in the horizontal direction and requires sheath flow focusing, the channel cannot be too high or too wide, so there is a limitation in throughput

Method used

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  • Particle sorting method based on acoustic artificial structure
  • Particle sorting method based on acoustic artificial structure
  • Particle sorting method based on acoustic artificial structure

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Embodiment Construction

[0029] In order to make the above objects, features and advantages of the present invention more clearly understood, the specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without departing from the connotation of the present invention. Therefore, the present invention is not limited by the specific embodiments disclosed below.

[0030] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", " Back, Left, Right, Vertical, Horizontal, Top, Bottom, Inner, Outer, Clockwise, Countercl...

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Abstract

The invention discloses a particle sorting method, device and equipment based on an acoustic artificial structure and a storage medium thereof. The method comprises the following steps: enabling the acoustic artificial structure to resonate through ultrasonic excitation; injecting a to-be-separated sample into the flow chamber, and capturing to-be-separated sample particles of which the radiation force is greater than a threshold value to the sound artificial structure by utilizing the sound radiation force generated by the resonance strong local sound field; particles flowing out of the flow chamber are collected, the radiation force of the particles being less than a threshold. According to the scheme provided by the invention, sheath flow or other modes are not needed to focus the sample, so that the channel can be wider, and the treatment flux is higher; compared with a surface wave device, the device used in the scheme is low in manufacturing cost. And the manual structure can be freely replaced flexibly and conveniently.

Description

technical field [0001] The invention relates to the technical fields of acoustic manipulation and microfluidics, in particular to a particle sorting method, device, equipment and storage medium based on an acoustic artificial structure. Background technique [0002] Isolation of specific particles or cells from mixed samples is important for many studies, including biomedical research, chemical analysis, and water treatment. After a certain period of development, microfluidic sorting technology has become a mainstream solution. Its significant advantage is that it can integrate technologies such as sound, electricity, magnetism, light and force with microfluidics, and has the characteristics of high precision, miniaturization and easy manipulation. These methods all rely on the force of the physical field on the particles. In the case of flow, different particles are subjected to different forces, resulting in different motion trajectories, so as to achieve the purpose of s...

Claims

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Application Information

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IPC IPC(8): B07B13/00
CPCB07B13/00
Inventor 郑海荣黄来鑫李飞蔡飞燕孟龙牛丽丽周伟林争荣
Owner SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI
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