Integrated reaction disc for biochemical analyzer and control method of integrated reaction disc

A technology of biochemical analyzer and reaction plate, which is applied in the field of biochemical analysis, can solve the problems of low accuracy of detection results, and achieve the effects of high proportioning accuracy, convenient washing, and improvement of test accuracy

Pending Publication Date: 2022-07-12
河南医学高等专科学校附属医院
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] In view of the deficiencies in the above-mentioned background technology, the present invention proposes an integrated reaction plate for a biochemical analyzer and its control method, which solves the technical problem of low accuracy of detection results of existing biochemical item detection devices

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  • Integrated reaction disc for biochemical analyzer and control method of integrated reaction disc
  • Integrated reaction disc for biochemical analyzer and control method of integrated reaction disc
  • Integrated reaction disc for biochemical analyzer and control method of integrated reaction disc

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Embodiment Construction

[0056] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, but not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0057] Special note: The description of the orientation or positional relationship indicated in the present invention is only based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying the indicated device or element. It must have a specific orientation, be constructed and ...

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Abstract

The invention discloses an integrated reaction disc for a biochemical analyzer and a control method of the integrated reaction disc. A to-be-detected sample storage cavity, a to-be-detected sample quantification cavity, a mixing cavity and a reagent cavity are connected through capillary channels, a diluent storage cavity and a diluent quantification cavity are connected, the mixing cavity and the reagent cavity are connected through capillary channels; each capillary channel is a curve-shaped hydrophobic channel, a specific relationship is formed between the centrifugal radius of each capillary channel and the centrifugal radius of each cavity, and the control method comprises quantitative control, mixing control, liquid preparation control, flushing control and temperature control. Quantitative proportioning, mixing, liquid preparation and early-stage centrifugation functions of a to-be-detected sample and a diluent can be realized only by controlling the reagent disc body to rotate clockwise and anticlockwise, the mixed liquid is high in proportioning precision and uniform in mixing, and meanwhile, liquid in each cavity cannot flow back, so that the accuracy of the reagent disc is improved. The liquid in each cavity can reliably flow according to a predetermined route.

Description

technical field [0001] The present invention relates to the technical field of biochemical analysis, in particular to an integrated reaction plate for a biochemical analyzer and a control method thereof. Background technique [0002] Interleukin-33 (IL-33) is a new member of the IL-1 family, which can not only function as a nuclear factor in the nucleus, but also be released outside the cell by damaged or necrotic cells as a cytokines play a role. The released IL-33 activates downstream IL-33 by isoforms composed of specific receptors, suppressor of tumorigenicity 2 (ST2) and IL-1 receptor auxiliary protein (IL-1RAcP). NF-κB and MAPKs signaling pathways further activate a variety of immune responses. IL-33 is abnormally expressed in a variety of tumors (such as lung cancer, breast cancer, colorectal cancer, etc.), participates in the occurrence, development and metastasis of tumors, and even plays a dual role of tumor-promoting and anti-tumor in the same type of tumor. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/00G01N35/02G01N35/04G01N33/50
CPCG01N35/02G01N35/00584G01N35/00623G01N35/00663G01N35/0092G01N35/00712G01N35/025G01N35/04G01N33/50G01N2035/0444
Inventor 岳颖何平申娟鲍应环陈月婵连晶瑶
Owner 河南医学高等专科学校附属医院
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