Integrated reaction disc for biochemical analyzer and control method of integrated reaction disc

Abstract

The invention discloses an integrated reaction disc for a biochemical analyzer and a control method of the integrated reaction disc. A to-be-detected sample storage cavity, a to-be-detected sample quantification cavity, a mixing cavity and a reagent cavity are connected through capillary channels, a diluent storage cavity and a diluent quantification cavity are connected, the mixing cavity and the reagent cavity are connected through capillary channels; each capillary channel is a curve-shaped hydrophobic channel, a specific relationship is formed between the centrifugal radius of each capillary channel and the centrifugal radius of each cavity, and the control method comprises quantitative control, mixing control, liquid preparation control, flushing control and temperature control. Quantitative proportioning, mixing, liquid preparation and early-stage centrifugation functions of a to-be-detected sample and a diluent can be realized only by controlling the reagent disc body to rotate clockwise and anticlockwise, the mixed liquid is high in proportioning precision and uniform in mixing, and meanwhile, liquid in each cavity cannot flow back, so that the accuracy of the reagent disc is improved. The liquid in each cavity can reliably flow according to a predetermined route.

Description

technical field [0001] The present invention relates to the technical field of biochemical analysis, in particular to an integrated reaction plate for a biochemical analyzer and a control method thereof. Background technique [0002] Interleukin-33 (IL-33) is a new member of the IL-1 family, which can not only function as a nuclear factor in the nucleus, but also be released outside the cell by damaged or necrotic cells as a cytokines play a role. The released IL-33 activates downstream IL-33 by isoforms composed of specific receptors, suppressor of tumorigenicity 2 (ST2) and IL-1 receptor auxiliary protein (IL-1RAcP). NF-κB and MAPKs signaling pathways further activate a variety of immune responses. IL-33 is abnormally expressed in a variety of tumors (such as lung cancer, breast cancer, colorectal cancer, etc.), participates in the occurrence, development and metastasis of tumors, and even plays a dual role of tumor-promoting and anti-tumor in the same type of tumor. Th...

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Problems solved by technology

[0008] In view of the deficiencies in the above-mentioned background technology, the present invention proposes an integrated reaction plate for a biochemical analyzer and its control method, which solves the technical problem of low accuracy of detection results of existing biochemical item detection devices

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