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Thermal block for receiving and controlling temperature of at least one laboratory sample vessel, manufacturing method and simulation method

A laboratory and sample technology, which is applied to a number of laboratory sample vessels and heat blocks for temperature adjustment, physical properties, computer implementation, and the field of manufacturing heat blocks, which can solve the problems of high cost and many manufacturing steps.

Pending Publication Date: 2022-07-15
EPPENDORF AG A BODY CORP INC UNDER THE LAWS OF GERMANY HAVING ITS REGISTERED OFFICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the cost of this production is relatively high because the number of manufacturing steps is also a source of failure.

Method used

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  • Thermal block for receiving and controlling temperature of at least one laboratory sample vessel, manufacturing method and simulation method
  • Thermal block for receiving and controlling temperature of at least one laboratory sample vessel, manufacturing method and simulation method
  • Thermal block for receiving and controlling temperature of at least one laboratory sample vessel, manufacturing method and simulation method

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Embodiment Construction

[0120] figure 1 An embodiment of a method 100 according to the invention for manufacturing a thermal block 1 according to the invention is schematically shown. In this method, Selective Laser Melting (SLM) is used as an additive manufacturing method for manufacturing the thermoblock. Here, the laser beam 5 is used to locally melt the powdery material 6 , here for example aluminum particles, in particular EOS aluminum AlSi10Mg. In this case an instrument EOS M 290, available from Electro Optical Systems, EOS GmbH, Kreiling, Germany, 82152, can be used. Here, the laser is computer-controlled focused on points of the powder-filled plane 6 previously defined by the 3D model.

[0121] The process starts with (not shown) dividing the 3D-CAD file data into layered models, the layer thickness of which is, for example, between 10 and 100 microns, wherein a 2D image is created for each layer. This file format is the industry standard STL file used for most layer-based 3D printing or ...

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Abstract

The invention relates to a thermal block for receiving and controlling the temperature of at least one laboratory sample vessel in a laboratory temperature control instrument, in particular in a PCR thermal cycler, which thermal block is produced by using a metal-containing material by means of an additive manufacturing method. The invention also relates to a method for producing a thermal block and to a computer-implemented method for simulating physical properties of a thermal block to be produced according to the invention.

Description

technical field [0001] The invention relates to a thermoblock for receiving and tempering at least one laboratory sample vessel, in particular a plurality of laboratory sample vessels, in a laboratory thermostat, in particular a PCR thermal cycler. Furthermore, the invention relates to a method for manufacturing a thermal block and a computer-implemented method for simulating the physical properties of a thermal block to be manufactured according to the invention. Background technique [0002] Such thermal blocks are used in particular in thermal cyclers defined for PCR (polymerase chain reaction). Thermal cyclers are laboratory tempering instruments in which a liquid sample is heated or cooled to a defined temperature level in a temperature cycle. In order to regulate the temperature (tempering), Peltier elements are usually used which are thermally coupled to the underside of the block. A temperature cycle here comprises at least two temperature levels, often two or thre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L7/00B01L9/06B33Y10/00B29C64/00B01L9/00B33Y80/00B22F10/00
CPCB01L7/52B01L2200/12B33Y10/00B01L9/523B33Y80/00B22F10/00B01L2300/0829Y02P10/25
Inventor 马尔特·基尔希罗斯纳弗洛里安·杜尔亨纳尔·塔什托雷·霍佩尔曼纽尔·佩措尔德
Owner EPPENDORF AG A BODY CORP INC UNDER THE LAWS OF GERMANY HAVING ITS REGISTERED OFFICE