Pharmaceutical composition containing 4-butoxy-beta-piperidinyl propiophenone compound as well as preparation method and application of pharmaceutical composition

Abstract

The invention discloses a pharmaceutical composition containing a 4-butoxy-beta-piperidinyl propiophenone compound, the administration route is external local administration, the dosage form is cream, the pharmaceutical composition is prepared by taking the 4-butoxy-beta-piperidinyl propiophenone compound or other pharmaceutically acceptable salts as an active ingredient and mixing the active ingredient and the cream, and the pharmaceutical composition is prepared by mixing the active ingredient and the cream. And adding a conventional auxiliary agent. The invention further discloses a preparation method and application of the pharmaceutical composition. The pharmaceutical composition is obviously different from other products in the prior art, the administration route is changed from oral administration to local administration, adverse reactions caused by oral administration are greatly reduced, meanwhile, a brand new clinical application is provided, and the pharmaceutical composition is applied to treatment of male ejaculation dysfunction.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a preparation composition for the treatment of male ejaculation dysfunction; in particular to a pharmaceutical composition containing 4-butoxy-β-piperidinyl propiophenone compounds and preparation thereof methods and applications. Background technique [0002] According to the "2013 Asia-Pacific Sexual Behavior and Sexual Satisfaction Survey Report", the incidence of premature ejaculation (PE) in male ejaculation dysfunction has reached 32%, and the total number of adult men in China is 460 million, that is to say, there are more than 150 million premature ejaculation patients. The results of a cross-sectional study conducted in 5 cities in Anhui Province, China showed that: in China, 34.62% of men complained of premature ejaculation. Premature ejaculation (PE) is the most common sexual dysfunction disease in men, which seriously affects the quality of sexual life of patients, c...

AI Technical Summary

Problems solved by technology

CN106692036A provides a preparation method of thermosensitive dyclonine hydrochloride gel, the gel prepared by this method is used for laryngeal anesthesia and lubrication during upper gastrointestinal endoscopy, and does not involve clinical evidence of male ejaculation disorder Applied therapy

So far, no products containing dyclonine and clinically applied to male ejaculation disorders have been listed on the market

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