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Overturning displacement full-sealing heat cover system and driving method

A fully-sealed, heat-covered technology, applied in biochemical equipment and methods, biomass post-treatment, bioreactors/fermenters for specific purposes, etc. Large, high production costs and other issues, to achieve the effect of improving experimental efficiency and accuracy, small overall structure size, reducing manufacturing cost and manufacturing difficulty

Pending Publication Date: 2022-07-29
3D BIOMEDICINE SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Furthermore, for a one-time use cartridge, the high production cost is unacceptable, so the thermal cover structure also needs to ensure low production cost and processing difficulty
Moreover, the volume of the heat cover structure should not be too large, otherwise it will be difficult to apply to the cartridge with limited internal space

Method used

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  • Overturning displacement full-sealing heat cover system and driving method
  • Overturning displacement full-sealing heat cover system and driving method
  • Overturning displacement full-sealing heat cover system and driving method

Examples

Experimental program
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Embodiment Construction

[0036] In order to understand the content of the present invention more clearly, detailed description will be given in conjunction with the accompanying drawings and embodiments.

[0037] The use of the hot lid system to heat the reaction wells during the library preparation process must simultaneously ensure the integrity of the library preparation cassette and the requirements of not affecting the operability of other functional components, that is, the hot lid (lid assembly) is essentially required not only to perform a single dimension In order to realize the normal closing and opening operation of the hot lid, it is also necessary to provide an appropriate displacement method to ensure that the operating space directly above the reaction well can be released when the hot lid is open for other functional components (such as pipettes) in the cassette to adjust. The reaction wells are operated. The more complex displacement requirement not only brings problems to the sealing...

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PUM

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Abstract

The invention relates to an overturning displacement full-sealing heat cover system and a driving method, the overturning displacement full-sealing heat cover system comprises a heat cover and a displacement driving module which are not fixedly connected with each other, and the separated external displacement driving module drives the heat cover in a card box to perform required single-degree-of-freedom overturning displacement. The required displacement movement of the heat cover is realized; after the heat cover is opened, a sufficient effective operation space is formed right above a PCR (Polymerase Chain Reaction) tube, so that other functional parts such as a pipettor and the like can be operated; the heat cover independently arranged in the clamping box can be simply and conveniently made of elastic sealing materials to ensure the sealing performance of the clamping box in the displacement process, and the heat cover is easy and convenient to manufacture, low in cost, especially small in size and suitable for instruments with narrow internal space, and is an ideal solution for heating the heat cover in the library preparation process.

Description

technical field [0001] The invention relates to the technical field of genetic testing, and in particular, to a system and a driving method for a full-sealing thermal cover with flip displacement. Background technique [0002] During library preparation PCR, to prevent the water in the main reaction well samples from evaporating and condensing on the PCR tube lid, it is usually necessary to heat the PCR tube lid. Compared with the method of adding paraffin oil to prevent evaporation, heating with a hot cover avoids the problem that the paraffin oil is not easily removed after the reaction is completed, and has become a commonly used solution. [0003] Most of the hot lids used in the prior art come from the structure of a thermal cycler, which corresponds to the fixed structure of a 96-well plate or a PCR strip tube. When heating is required, the movable structure is driven by a motor to compress the PCR tube lid and use the hot lid ( Such as PI heating film) to heat the PC...

Claims

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Application Information

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IPC IPC(8): C12M1/36C12M1/34
CPCC12M1/36C12M1/34C12M1/00
Inventor 王海保陈居勇王兆松曹震廷洪志强
Owner 3D BIOMEDICINE SCI & TECH CO LTD
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