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Medicine for treating hypertension and preparation method

A high blood pressure and drug technology, which is applied in the field of drugs for the treatment of high blood pressure and its preparation, can solve problems such as the lack of compound effects of unilateral prescriptions, large toxic and side effects of drugs, and difficult standardization of syndrome differentiation and treatment, so as to expand renal arteries, treat high blood pressure, and lower blood pressure Effect

Inactive Publication Date: 2005-03-30
金陵药业股份有限公司技术中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is still difficult to standardize the treatment based on syndrome differentiation, and the treatment of disease differentiation is still immature, and the single prescription lacks compound effects, and the use of decoction is inconvenient
Diuretics, vasodilators, sympathetic blockers, calcium ion antagonists combined with angiotensin-converting enzyme inhibitors are commonly used in the treatment of hypertension in Western medicine, but the drugs have large toxic and side effects and the curative effect is not stable enough

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Take the following raw materials by weight:

[0038] Prunella vulgaris 2000g Scutellaria baicalensis 1667g Oyster 5000g

[0039] Banxia 1667g Dannanxing 1000g Stiff silkworm 1667g

[0040] Seaweed 1667g Alisma 2500g

[0041] The above-mentioned crude drug is prepared according to the following procedures:

[0042] a. Add water to decoct oysters and silkworms twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoction, filter, concentrate under reduced pressure to a relative density of 1.08 (70°C), spray dry, and dry The extract is ready for use;

[0043] b. Soak Prunella vulgaris and other six traditional Chinese medicines in water for half an hour, decoct twice, add 10 times the amount of water each time, decoct for 1 hour, combine the decoctions, centrifuge, adsorb on the resin, and elute the resin with 70% ethanol. Collect the alcoholic liquid, filter it, recycle the ethanol as much as possible, spray dry it, and obtain the dry ext...

Embodiment 2

[0046] The granular powder with active components prepared in Example 1 was divided into 1000 hard capsules to make a hard capsule for treating hypertension.

Embodiment 3

[0048] The granular powder with active components prepared in Example 1 is mixed with commonly used adjuvants for tablets such as lubricants, disintegrants, binders, etc., and compressed into tablets to prepare a tablet for treating hypertension.

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Abstract

The present invention relates to a Chinese medicine for curing hypertension and its preparation method. It is made up by using 8 Chinese medicinal materials of prunella spike, scutellaria root, oyster shell, pinellia tuber, bile-processed arisaema root, silkworm, sargassum and alisma tuber as raw material and adopting the steps: decocting oyster shell and silkworm, reduced pressure concentrating and spray-drying; decocting other 6 Chinese medicinal materials, resin adsorption, eluting resin with ethyl alcohol, collecting alcohol liquor, filtering, recovering ethyl alcohol completely, spray-drying, mixing said dried extract powders uniformly and making them into various oral dosage forms.

Description

Technical field: [0001] The invention relates to a medicine for treating hypertension and a preparation method thereof. Background technique: [0002] Hypertension is a common disease. According to literature records, the prevalence rate in my country is generally 3-9%, and there are at least 50 million patients in my country. The prevalence rate in European and American countries is as high as 10-20%, and the average prevalence rate in the world is 10%. Among the major fatal diseases such as coronary heart disease and cerebrovascular disease, the morbidity and mortality of cardiovascular and cerebrovascular diseases are closely related to the level of hypertension. Therefore, all countries in the world attach great importance to the research and development of hypertension. Prevention and treatment. At present, there are many types of antihypertensive drugs used in the treatment of hypertension at home and abroad, but some antihypertensive drugs, especially chemical drugs...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P9/12
Inventor 周仲瑛王兴旺徐向阳孙晔张蕙万辉张庆晓田丽娟陈钟陈希张杰倪洁张春来
Owner 金陵药业股份有限公司技术中心
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