Device and method for non-invasive investigating biofluid concentration using optoacoustic frequency spectrum
一种生物流体、生物体的技术，应用在测量装置、生物测试、血液表征装置等方向，能够解决难低浓度的物质浓度、不能精确地测量生物流体浓度、吸收带相互重叠等问题，达到精确测量的效果
Inactive Publication Date: 2006-05-03
SAMSUNG ELECTRONICS CO LTD
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Problems solved by technology
Second, the absorption bands of the components may overlap with each other
Third, since biological tissue is prone to scattering, it is difficult to predict the concentration of substances with low concentrations
However, since the transmission characteristics of sound waves can vary depending on the individual and the individual's body part, conventional fluid measurement devices cannot accurately measure biofluid concentrations, which is also a problem with other conventional measurement devices utilizing photoacoustic spectroscopy
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[0047] The device and method for non-invasively measuring the concentration of a biological fluid will be described in detail below with reference to the accompanying drawings. The same reference numerals in different figures denote the same elements.
[0048] image 3 is a block diagram of an apparatus for non-invasively measuring the concentration of a biological fluid according to an embodiment of the present invention. see image 3 , the device 50 for the non-invasive measurement of biological fluid concentration includes a light source 51; an acoustic signal generator 53 located near the measured object, and an optical signal is applied to the acoustic signal generator; a signal detection device located on the other side of the measured object 55, a light detector (not shown) for detecting the intensity (E) of the light signal, a controller, a calculator, and an indicator 57. Wherein, the controller, the calculator and the indicator 57 are connected with the light sour...
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The present invention provides an apparatus and method for non-invasively measuring the concentration of biological fluids using photoacoustic spectroscopy. The apparatus includes: a light source that irradiates a light signal having a predetermined wavelength band that can be absorbed into a predetermined component of the living body on a predetermined portion of the living body; an acoustic signal generator that generates light in the vicinity of the predetermined portion of the living body an acoustic signal A1 having a frequency band similar to that of a photoacoustic signal PA generated when a light signal is absorbed into a predetermined component of a living body; a signal detector that detects the photoacoustic signal PA and the acoustic signal and A calculator that calculates a signal compensation value (N) based on the intensity (E) of the light signal from the light source and the photoacoustic signal (PA) and acoustic signal A2 input from the signal detector, and calculates the concentration (C) of a predetermined component .
Description
technical field [0001] The present invention relates to devices and methods for non-invasively measuring the concentration of biological fluids, and more particularly, to a device and method for non-invasively measuring the concentration of biological fluids using photoacoustic spectroscopy. Background technique [0002] Although research has been carried out worldwide on methods for measuring glucose values using light without taking blood, they have never succeeded in providing any distinctive results. Various measurement techniques, such as near-infrared absorption, far-infrared absorption, Raman (Ramann) spectroscopy, polarization (polarization) rotation, stimulated Raman (Stimulate Ramann), dispersion measurement, temperature measurement, statistical analysis and preprocessing research, have been For in vivo measurement of biological fluid concentrations. However, because each of these conventional measurement techniques has its own drawbacks, they can never be readi...
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IPC IPC(8): G01N21/17G01N33/487G01N33/66A61B5/00G01N29/00A61B5/145A61B5/1455A61B8/00G01N21/00G01N21/49
CPCA61B5/0059A61B5/0095A61B5/14532A61B5/1455G01N21/1702G01N21/49G01N2021/1706A61B8/00
Inventor 全桂珍尹吉源黄寅德
Owner SAMSUNG ELECTRONICS CO LTD