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Chinese rose extract and its preparing method and use

A technology of Chinese rose flower and water extract, which is applied in the field of preparation of drugs for treating diabetes, can solve the problems that need to be carried out, and achieve the effect of small dosage, high safety, and clear hypoglycemic effect

Inactive Publication Date: 2006-07-05
CSPC ZHONGQI PHARM TECH (SHIJIAZHUANG) CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The applicant applied for "Chinese rose extract and its preparation method and use" on December 28, 2002, and clarified the pharmacological effects of the Chinese rose extract, but the qualitative and more in-depth pharmacodynamic studies of the extract still need to be carried out. pending

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment one: the preparation of Chinese rose water extract (I)

[0031] Take 1kg of Chinese rose medicinal materials, slightly smash it, add 10 times the amount of water to reflux for extraction, extract a total of 3 times, 1 hour each time, combine the extracts, filter, and concentrate the filtrate to an extract containing 1g of crude drugs per 1ml, and obtain a total of extracts. The paste is about 330g.

Embodiment 2

[0032] Example 2: Preparation of Chinese rose ethanol extract (II)

[0033] Take 1kg of Chinese rose medicinal materials, slightly smash it, add 8 times the amount of 45% ethanol for extraction at room temperature, extract 3 times in total, 8 hours each time, combine the extracts, filter, and concentrate the filtrate to a concentration of 1g crude drug per 1ml. Extract, a total of about 150g of extract.

Embodiment 3

[0034] Example 3: Preparation of Chinese rose ethanol extract (II*)

[0035] Take 1kg of Chinese rose medicinal materials, slightly smash them, add 8 times the amount of 60% ethanol for reflux extraction, extract 3 times in total, 1 hour each time, combine the extracts, filter, and concentrate the filtrate to an extract containing 1g of crude drugs per 1ml, A total of about 200g of extract was obtained.

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PUM

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Abstract

The present invention relates to Chinese rose extract, its preparation process and application in preparing medicine for treating diabetes. Animal experiment shows that Chinese rose extracts obtained via different extraction processes have obvious blood sugar reducing effect and may be used in preparing medicine for treating diabetes.

Description

technical field [0001] The present invention relates to Chinese rose extract and its extraction method, as well as its application in preparing medicine for treating diabetes. Background technique [0002] Diabetes mellitus is a common metabolic disease. It is a disorder of glucose metabolism caused by an absolute or relative lack of insulin secretion, which in turn leads to a disorder of fat and protein metabolism. Therefore, with the aging of the world population and the improvement of living standards, the dietary structure Due to unreasonable and genetic factors, diabetes has become a common and frequently-occurring disease. Because it involves the whole body system, many fatal complications occur, which seriously threatens human life and health. [0003] Diabetes can generally be divided into the following types: A, insulin-dependent (referred to as type I diabetes); B, non-insulin-dependent (referred to as type II diabetes); C, malnutrition diab...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/35A61K36/738A61K133/00A61P3/10C07B63/00C07D311/30C07H1/08C07H17/07
Inventor 刘振涛李清娟刘亚英陈卫平徐峰梁敏
Owner CSPC ZHONGQI PHARM TECH (SHIJIAZHUANG) CO LTD