Mint oil preparation for treating obstructive sleep apnea and low ventilation syndrome

A sleep apnea and peppermint oil technology, which is applied in aerosol delivery, respiratory diseases, medical preparations containing active ingredients, etc., to achieve the effects of reducing dosage, protecting normal physiological barriers, and replenishing water loss

Inactive Publication Date: 2006-10-04
徐湄
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far there are no literature and patents related to peppermint oil preparations for the treatment of OSAHS related reports

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 The clinical experiment of the present invention before and after treating OSAHS patient polysomnography:

[0015] Experiment is with random, control principle design clinical trial scheme, in order to investigate the degree of pharyngeal stenosis or collapse of reducing OSAHS patient of the present invention, alleviate the clinical effect of hypoxemia, 60 light, moderate OSAHS patient (polysomnography) The apnea hypopnea index (AHI) was 5-30 times / h; the average age was (55.9±13.6) years old, from 32 to 79 years old; the body mass index (BMI) was (25.8±2.6) kg / m 2 ) participated in this 2-week randomized, controlled clinical treatment trial. The control group (because there is no effective drug for the treatment of OSAHS now) adopts the composition ratio of glycerin and distilled water in the peppermint oil preparation, and the composition ratio of peppermint oil is replaced by distilled water to make a control oily solution.

[0016] The experimental sub...

Embodiment 2

[0023] Components, proportioning and preparation of embodiment 2 peppermint oil preparation of the present invention:

[0024] (1), the preferred percentage by weight of the prescription of preparation medicine of the present invention is:

[0025] Peppermint oil 0.5~1.5%

[0026] Glycerin 32-34%

[0027] Distilled water 64.5-67.5%.

[0028] (2), the optimum weight percent of medicine of the present invention is:

[0029] Peppermint Oil 1%

[0030] Glycerin 33%

[0031] Distilled water 66%.

[0032] The production method that above-mentioned each component is made into medicine of the present invention is:

[0033] (1), get peppermint, at the full flowering stage, after drying at room temperature, 100 g of the sample is pulverized, and the volatile oil is extracted by steam distillation to obtain the peppermint oil component and measure the volatile oil content.

[0034] (2) Peppermint oil, glycerin, and distilled water are prepared into a transparent solution according...

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PUM

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Abstract

The invention provides a mint oil preparation which comprises mint oil, glycerin, and distilled water.

Description

technical field [0001] The invention relates to a peppermint oil drop or spray for treating obstructive sleep apnea-hypopnea syndrome (OSAHS) patients with pharyngeal stenosis or collapse by oral administration. Background technique [0002] Sleep apnea-hypopnea syndrome (SAHS) is a state-dependent syndrome. Due to its predisposing factors such as obesity and narrowing of the upper airway anatomy, it will produce a state-dependent decrease in muscle tone, resulting in upper The spectrum of recurrent airway collapse is described as beginning with simple snoring (pharyngeal vibrations), progressing to airflow limitation (hypopnea), and finally complete cessation of breathing (apnea). The main symptoms are snoring, observable apnea, and excessive daytime sleepiness. The immediate physiological consequences are hypoxemia, recurrent sympathetic impulses, increased cardiac workload, and recurrent cerebral arousal; the need for arousal to restore airway patency results in severe s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/534A61K9/12A61K9/08A61P11/00A61K9/00
Inventor 徐湄
Owner 徐湄
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