Use of vMIP and congeneric E protein ligand in pharmacy

A protein and drug technology, which is applied to the application field of vMIP and its similar E protein ligands in pharmaceuticals, can solve problems such as impossible to talk about, leukocyte decline, etc., and achieves good prospects and improves the effect of medicinal effects.
CN1470284AInactive Publication Date: 2004-01-28JINAN UNIVERSITY
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
JINAN UNIVERSITY
Publication Date
2004-01-28
Estimated Expiration
Not applicable Β· inactive patent
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Abstract

The invention refers to the new use of HHV8 chemotactic factor vMIP and the ramification and other albumen factor in the pharmacy field, especially refers to the use in preventing and curing the SARScorresponding Coronaviridae infection. The invention uses vMIP-I, vMIP-II, vMIP-III of recombined HHV8, combines the process that the E albumen of SARS coronaviridae can resist the virus infecting the cell, the invention has prominent effect on decreasing the infection rate of SARS coronaviridae to kidney cell Vero E6, the mechanism is that the combination with homologous E albumen receiver prevents the infection, so it is possible that human control SARS disease effectively.
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Description

Technical field

[0001] The present invention relates to the new use of the viral chemokine vMIP and its derivatives and other ligand protein-like factors that can be combined with the SARS coronavirus E protein pseudo-receptor in the pharmaceutical field, in particular to the preparation and prevention of human SARS (severe acute Respiratory Syndrome) in the application of drugs related to coronavirus infections. Background technique

[0002] Since November 2002, the SARS coronavirus has spread rapidly around the world in just six months, with more than 8,000 cases and more than 500 deaths.

[0003] At the beginning of the SARS epidemic, people thought it was a myxovirus-rich virus, but soon from a transmission electron microscope photo, people began to believe that the culprit of SARS was the coronavirus, and soon it was confirmed and completed by laboratories in Canada, China, and the United States almost at the same time. Genome sequencing of the virus, currently known SARS vi...

Claims

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