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Kecuocryptone gel and preparation process thereof

The technology of Kecuo cryptonone gel and tanshinone powder is applied in the field of Kecuo cryptonone gel and its preparation technology, and can solve the problems of large skin irritation, easy scab formation, poor permeability and the like, and achieve less skin irritation. , good stability and improved efficacy

Active Publication Date: 2004-03-24
HEFEI LIFEON PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently on the market, gramacryptone emulsion and tincture for acne treatment are more irritating to the skin, easy to scab, have a greasy feeling, poor permeability, affect the appearance of patients after application, and have poor stability under the temperature of different regions , perishable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0039] Make 1000 grams of Acnecryptone gel, weigh 1.5 grams of tanshinone powder, 1.5 grams of trimethoprim, 3 grams of vitamin A, 3 grams of vitamin E, 12 grams of carbomer 940, disodium edetate 0.1 gram, 80 grams of propylene glycol, 50 grams of carbitol, 20 grams of lauryl alcohol, 1 gram of ethyl paraben, 250 grams of 95% ethanol, and an appropriate amount of water. Include the following steps:

[0040] Firstly, take the disodium salt of ethylenediaminetetraacetic acid according to the above weight, add water to dissolve it, add carbomer, stir evenly, and let it stand for 12 to 24 hours to obtain carbomer gel.

[0041] Its two, get 95% ethanol by above-mentioned weight, propylene glycol, carbitol are mixed, then add trimethoprim, tanshinone powder, lauryl alcohol, ethylparaben, vitamin A and vitamin E, after stirring to dissolve, namely Get a mixture.

[0042] Finally, combine the mixed solution with the carbomer gel, adjust the pH value to 5-7 with triethanolamine, and ...

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PUM

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Abstract

The present invention relates to a kecuocryptone gel and its preparation process. Said kecuocryptone gel is composed of salvia miltiorrhiza powder, trimethoprim, vitamin A, vitamin E, propylene glycol, laurinol, ethyl P-hydroxyhenzoate, ethyl alcohol and carbomer gel. Its preparation process includes the following steps: dissolving disodium ededate salt by adding water, adding carbomer, stirring, standing still to obtain carbomer gel; mixing ethyl alcohol, propylene glycol and carbitol uniformly, adding trimethoprim, salvia miltiorrhiza, laurinol, ethyl p-hydroxybenzoate, vitamin A and vitamin E, stirring them and combining them with carbomer gel, using triethanolamine to regulate pH value to 5-7 and stirring them uniformly so as to obtain the invented product.

Description

technical field [0001] The invention belongs to Chinese and western medicine gel preparations, in particular to gramacryptone gel and a preparation process thereof. Background technique [0002] Acne is a chronic inflammatory skin disease of the hair follicles and sebaceous glands. The incidence rate accounts for about 20% to 24% of the population. It is more common in men and women in adolescence, and it can also occur in men after adulthood. Currently on the market, gramacryptone emulsion and tincture for acne treatment are more irritating to the skin, easy to scab, have a greasy feeling, poor permeability, affect the appearance of patients after application, and have poor stability under the temperature of different regions , perishable. Contents of the invention [0003] The purpose of the present invention is to provide a skin that is less irritating to the skin, is not easy to scab, has no greasy feeling, has good permeability, is easy to spread, does not affect t...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/505A61P17/10
Inventor 童玉新
Owner HEFEI LIFEON PHARMA
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