Kecuocryptone gel and preparation process thereof

The technology of Kecuo cryptonone gel and tanshinone powder is applied in the field of Kecuo cryptonone gel and its preparation technology, and can solve the problems of large skin irritation, easy scab formation, poor permeability and the like, and achieve less skin irritation. , good stability and improved efficacy

Active Publication Date: 2004-03-24
HEFEI LIFEON PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently on the market, gramacryptone emulsion and tincture for acne treatment are more irritating to the skin, easy to scab, have a greasy feeling, p

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0038] Examples:

[0039] Make 1000 grams of acne ketone gel, weigh 1.5 grams of tanshinone powder, 1.5 grams of trimethoprim, 3 grams of vitamin A, 3 grams of vitamin E, 12 grams of carbomer 940, and disodium edetate 0.1 g, 80 g of propylene glycol, 50 g of carbitol, 20 g of lauryl alcohol, 1 g of ethyl paraben, 250 g of 95% ethanol, and an appropriate amount of water. Including the following steps:

[0040] First, take ethylenediaminetetraacetic acid disodium salt according to the above weight, add water to dissolve it, add carbomer and stir evenly, let it stand for 12-24 hours to obtain carbomer gel.

[0041] Second, mix 95% ethanol, propylene glycol, and carbitol according to the above weight, then add trimethoprim, tanshinone powder, lauryl alcohol, ethyl paraben, vitamin A and vitamin E, and stir to dissolve it. Get the mixture.

[0042] Finally, combine the mixture with the carbomer gel, adjust the pH value to 5-7 with triethanolamine, and stir evenly to obtain the graminon...

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PUM

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Abstract

The present invention relates to a kecuocryptone gel and its preparation process. Said kecuocryptone gel is composed of salvia miltiorrhiza powder, trimethoprim, vitamin A, vitamin E, propylene glycol, laurinol, ethyl P-hydroxyhenzoate, ethyl alcohol and carbomer gel. Its preparation process includes the following steps: dissolving disodium ededate salt by adding water, adding carbomer, stirring, standing still to obtain carbomer gel; mixing ethyl alcohol, propylene glycol and carbitol uniformly, adding trimethoprim, salvia miltiorrhiza, laurinol, ethyl p-hydroxybenzoate, vitamin A and vitamin E, stirring them and combining them with carbomer gel, using triethanolamine to regulate pH value to 5-7 and stirring them uniformly so as to obtain the invented product.

Description

technical field [0001] The invention belongs to Chinese and western medicine gel preparations, in particular to gramacryptone gel and a preparation process thereof. Background technique [0002] Acne is a chronic inflammatory skin disease of the hair follicles and sebaceous glands. The incidence rate accounts for about 20% to 24% of the population. It is more common in men and women in adolescence, and it can also occur in men after adulthood. Currently on the market, gramacryptone emulsion and tincture for acne treatment are more irritating to the skin, easy to scab, have a greasy feeling, poor permeability, affect the appearance of patients after application, and have poor stability under the temperature of different regions , perishable. Contents of the invention [0003] The purpose of the present invention is to provide a skin that is less irritating to the skin, is not easy to scab, has no greasy feeling, has good permeability, is easy to spread, does not affect t...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61K31/505A61P17/10
Inventor 童玉新
Owner HEFEI LIFEON PHARMA
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