Process for producing water-soluble hemostatic etamine
A technology of hemostatic gauze and production process, which is applied in the field of production process of water-soluble hemostatic gauze, can solve the problems of polluting the environment, waste is not easy to rot, etc., and achieve the effect of avoiding the formation of adhesion and promoting wound healing
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Embodiment 1
[0011] (1) Solution A: 80% alcohol containing 2.5mol / L chloroacetic acid. Submerge the degreased gauze in the solution A at a temperature of 40-50°C and shake for 6 hours.
[0012] (2) Solution B: in 80% alcohol containing 4.0 mol / L sodium hydroxide. Put the gauze treated with solution A at a temperature of 40-50°C and shake for 6 hours.
[0013] (3) Wring out the gauze treated with solution B, put it into 95% alcohol, then adjust the pH value to 6.5-8.5 with concentrated hydrochloric acid; then immerse it in 95% alcohol, scrub it three times, wring it dry, and put it in the temperature of 25-30°C , Dry in a drying room with a humidity of 40-55°C; when the gauze is 90% dry, pull the gauze flat; after the gauze is completely dry, cut it according to different specifications and put it into a packaging bag.
[0014] (4) Gamma ray irradiation sterilization, the minimum absorbed dose is 25KGy.
Embodiment 2
[0016] (1) Solution A after titration embodiment 1 reaction is the 70% alcohol that contains 1.5mol / L chloroacetic acid. It is supplemented as 70% edible alcohol containing 2.5mol / L chloroacetic acid.
[0017] (2) Titration The solution B after the reaction of Example 1 is 80% alcohol containing 2.5mol / L sodium hydroxide. Make it up to 80% alcohol containing 4.0 mol / L sodium hydroxide.
[0018] (3) All the other steps are the same as in Example 1.
Embodiment 3
[0020] (1) Solution A after titration embodiment 1 reaction is the 70% alcohol that contains 1.6mol / L chloroacetic acid. Make it up to 70% alcohol containing 2.0mol / L chloroacetic acid.
[0021] (2) Titration The solution B after the reaction of Example 1 is 70% alcohol containing 2.2mol / L sodium hydroxide. Make it up to 70% alcohol containing 3.0 mol / L sodium hydroxide.
[0022] (3) All the other steps are the same as in Example 1.
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