59results about How to "With hemostatic function" patented technology

The invention relates to a medical chitosan antiseptic dressing, which takes chitosan fiber as a raw materials and is prepared by the following steps of spraying silver-loaded nano titanium dioxide particles on the chitosan fiber to prepare a dressing product, wherein the silver-loaded nano titanium dioxide particles accounts for 0.1-2wt% of the dressing; and drying the dressing product, cutting,packaging, sterilizing to obtain the product. The spray technology is as follows: spinning the chitosan fiber, cutting into short fiber, spraying the silver-loaded nano titanium dioxide particles on the chitosan short fiber, and preparing into the chitosan product. The invention has the advantages of imbibing function, moisture function, hemostasis function and antibiosis capability, and is a good medical dressing.

The invention relates to a traditional Chinese medicine parasite-expelling reagent, which comprises the following traditional Chinese medicine raw materials in parts by weight: 10-20 parts of santolina chamaecyparissus, 10-20 parts of herba pogostemonis, 10-20 parts of herbaagrimoniae, 10-20 parts of herba schizonepetae, 10-20 parts of sweet basil, 10-20 parts of fructusarctii, 10-20 parts of rhizoma atractylodis, 10-20 parts of herbamenthae, 10-20 parts of radix notoginseng, 10-20 parts of rhizoma acori tatarinowii, 10-20 parts of folium artemisiae argyi, 10-20 parts of herbaasari, 10-20 parts of floscaryophylli, 10-20 parts of radix saposhnikoviae, 10-20 parts of ramulus cinnamomi, 10-20 parts of rhizoma cyperi, 10-20 parts of radix angelicae dahuricae, 10-20 parts of radix sophorae flavescentis, 10-20 parts of radix angelicae pubescentis and 10-20 parts of fructus evodiae. The traditional Chinese medicine parasite-expelling reagent adopts multiple natural phytoextraction constituents, thus being natural and mild; the traditional Chinese medicine parasite-expelling reagent can prevent biting of mosquitos and insects, also can fast relieve the discomfortableness due to biting of mosquitos, the traditional Chinese medicine parasite-expelling reagent is pure and mild, irritation-free, and gives skin safer care. People can keep away from invasion of mosquitos in summer. The traditional Chinese medicine parasite-expelling reagent is natural and mild, safe, non-greasy and close fitted and comfortable.

The invention provides a method for preparing bleeding stopping oxidized celluloses in ramie oxidation degumming procedures. The method includes smashing raw ramie to obtain short fibers and soaking the short fibers to sufficiently moisten the short fibers and allow the short fibers to sufficiently swell; mixing the pretreated raw ramie short fibers and degumming solution with one another to obtain mixtures, heating the mixtures, then preserving heat, sufficiently removing colloid in the raw ramie by the aid of oxidability of specific oxidizing agents and simultaneously oxidizing celluloses with active hydroxyl to obtain oxidized celluloses with a large quantity of carboxyl; soaking oxidized and treated fibers by the aid of organic solvent aqueous solution and removing the unreacted oxidizing agents; separating the oxidized celluloses from water and carrying out drying treatment on the oxidized celluloses to ultimately obtain the powdery bleeding stopping oxidized celluloses. The method has the advantages that processes are simple, the original two working procedures are combined into a single working procedure, accordingly, the total reaction time can be shortened, medicines and the cost can be saved, and the efficiency can be greatly improved; the bleeding stopping oxidized celluloses which are products prepared by the aid of the method are high in bleeding stopping speed and bleeding stopping efficiency and can be widely applied to quickly stopping bleeding under conditions of war wound, trauma and the like, and stable effects can be realized.

The invention relates to a mixed preparation method of hyacinth bletilla effective components and a gel, and particularly relates to a method for preparing a hemostatic gel through polymerization of a hyacinth bletilla extract and hyaluronic acid and application of the hemostatic gel. Hyacinth bletilla and hyaluronic acid are used as raw materials, so that the hydrogel has high elasticity and certain mechanical strength and facilitates release of the hyaluronic acid, thereby ensuring that the hydrogel can be used as an injection hydrogel. By regulating the amount of the hyacinth bletilla and the concentration of the sulfhydrylated hyaluronic acid, hydrogels with different mechanical parameters can be obtained, thereby obtaining the hydrogel having a hemostatic function. The hyaluronic acid is an in vivo inherent component, can promote growth of cells and is fine in biocompatibility. The hyaluronic acid in the hydrogel obtained by the invention is easier to dissociate.

The invention provides a hemostatic sponge/drug-loaded fiber mat/hemostatic sponge compound and a preparation method thereof, and belongs to the technical field of polymeric medical materials. The compound has a three-layer sandwich structure, and comprises two hemostatic sponges and a drug-loaded fiber mat arranged between the two hemostatic sponges. The invention also provides the preparation method of the hemostatic sponge/drug-loaded fiber mat/ hemostatic sponge compound. The drug-loaded fiber mat is completely wrapped with the hemostatic sponges, the three layers are structurally closely connected and have no gaps, the hemostatic sponges have an obvious three-dimensional network structure, and apertures are connected, so the hemostasis function and the postoperative recurrence prevention function are realized.

The invention relates to the field of medicinal dressings and in particular relates to a multifunctional liquid dressing and a preparation method thereof. The multifunctional liquid dressing comprises the following components in parts by mass: 2-8 parts of polyvinyl butyral, 0.5-0.8 part of sodium alginate-polyvinylpyrrolidone, 0.2-0.6 part of nano-silver-chitosan, 0.1-0.4 part of sodium carboxymethylcellulose, 0.1-0.4 part of carrageenan, 0.1-0.4 part of menthol and 91-97 parts of absolute ethyl alcohol. The multifunctional liquid dressing disclosed by the invention is waterproof, breathable and visible in wound, can prevent infection and contributes to wound healing.

The invention relates to hemostatic and antibacterial PU (polyurethane) dressing and preparation method thereof. The PU dressing comprises the following ingredients in parts by weight: 30-50 parts ofdehydrated polyethylene glycol, 1-10 parts of chitosan, 1-10 parts of usnic acid, 5-10 parts of 1% acetum, 1-5 parts of glycerol, 20-40 parts of toluene diisocyanate, 0.5-2 parts of nano-titanium dioxide, 1-20 parts of polyether polyol, 0.5-1.5 parts of stannous octoate, 0.5-1.5 parts of dimethylethanolamine and 0.5-5.0 parts of a silicon surfactant. The preparation method of the PU dressing comprises the following steps: A, weighing the chitosan and the usnic acid, adding the chitosan and the usnic acid into the 1% acetum, stirring the 1% acetum to dissolve the chitosan and the usnic acid, performing standing after the chitosan and the usnic acid are completely dissolved and filtering out undissolved substances, so as to obtain solution A; B, preparing a prepolymer: mixing the solution A,the dehydrated polyethylene glycol, the glycerol and the toluene diisocyanate, stirring the mixture and performing a reaction under a heat preservation condition, so as to obtain the prepolymer; C, foaming: uniformly mixing the polyether polyol, the stannous octoate, the dimethylethanolamine and the silicon surfactant, adding the nano-titanium dioxide into the mixture, stirring the mixture, adding the prepolymer into the mixture, uniformly mixing the mixture, foaming the mixture and curing the foamed mixture, so as to obtain the PU dressing. The PU dressing provided by the invention not onlyhas a hemostatic function, but also has broad spectrum bactericidal property.

The invention relates to a one-way valve for infusion. The one-way valve comprises an upper housing, a lower housing, a latex sphere and a spring, wherein infusion channels are respectively formed in the upper housing and the lower housing; a supporting separating plate with a circular through hole is arranged on the upper end surface of the lower housing; the lower housing and the upper housing are integrally fixed in an adhering manner, and a tapered hollow cavity is formed between the lower housing and the upper housing; the latex sphere and the spring are arranged in the tapered hollow cavity; the bottom end of the spring is fixed on the supporting separating plate at the lower housing and while the top end of the spring is used for supporting the latex sphere at the upper part of the tapered hollow cavity; and the latex sphere blocks below the outlet of the infusion channel of the upper housing. The one-way valve for infusion is reasonable in structure and convenient and reliable in use, and has the function of stopping blood returning, so that the safety in infusion is ensured; and the one-way valve for infusion is an ideal one-way valve for infusion, which is suitable for being arranged on a medical infusion device, and can ensure the one-way flow in infusion and blood transfusion.

The invention relates to a preparation method of oxidized nano bacteria cellulose, belonging to the related fields of biomedical materials and medical appliances. The method comprises the following steps: performing pretreatment and purification treatment on nano bacteria cellulose film to obtain purified nano bacteria cellulose, and shearing into wafers or square slices of different specifications; placing sheared nano bacteria cellulose in a clean wide-necked bottle or a wide-necked bottle holding a nitric acid solution with appointed concentration, and introducing NO2/N2O4 gas generated by reaction between copper powder and concentrated nitric acid to the wide-necked bottle so as to oxidize the nano bacteria cellulose; and taking out the sample after appointed time, and repeatedly cleaning with deionized water to obtain oxidized nano bacteria cellulose containing carboxyl group on C6 position. The prepared oxidized nano bacteria cellulose has excellent degradation property, biocompatibility and cellular affinity, excellent bleeding arresting performance and mechanical properties, and excellent water permeation, gas permeation, guiding and moisture absorption effects, and has higher application value in the aspects of implantation materials and wound bleeding arresting materials.

The invention belongs to medical auxiliary apparatuses, in particular discloses a nasal meatus breathing tampon tube, comprising a breather tube and a hemostatic layer 1 which is coated on the outer surface of the breather tube 2; the hemostatic layer is a spongy layer of which the thickness is at least 1mm. For the breather tube, the inner diameter is 3mm-10mm, the outer diameter is 5mm-12mm, and the axial length is 25mm-75mm; the axial length of the spongy layer is 20-70mm, and the axial length of the sponge layer is smaller than that of the breather tube, one end of the sponge layer aligns with one end of the breather tube, and the other end thereof is shorter than that of the breather tube. Through holes 3 are arranged on the nasal meatus breathing tampon tube, the spacing of the adjacent through holes is 8mm-10mm, and the aperture is 3mm-5mm. As the nasal meatus breathing tampon tube of the invention is composed of the breather tube and the spongy layer, and the tube wall is provided with through holes, therefore, the tampon tube has the characteristics of breathing, plasticity and hemostasis, increases comfort of patients, and has simple preparation and convenient use.

The invention discloses a panax notoginseng loaded hemostatic tissue repair membrane. The panax notoginseng loaded hemostatic tissue repair membrane comprises a hemostatic layer and a tissue membrane repair layer, wherein the hemostatic layer is prepared by mixing panax notoginseng and/or dencichine with natural high polymer materials; the tissue membrane repair layer is prepared by performing electrostatic spinning on panax notoginseng and/or dencichine and an electrostatic spinning material for tissue repair; and in the tissue membrane repair layer, the panax notoginseng and/or dencichine accounts for 5-30 percent of the mass of the tissue membrane repair layer. The tissue repair membrane disclosed by the invention has a good hemostatic function, is conveniently operated by a doctor, realizes hemostasis, does not influence the original repair effect of the tissue repair membrane and is particularly suitable for repairing tissues of easily bleeding parts.

The invention provides a traditional Chinese medicine insect-expelling additive. The additive is characterized by being prepared from the following medicinal raw materials in parts by weight: 10-20 parts of rhizoma atractylodis, 10-20 parts of peppermint, 10-20 parts of shinyleaf pricklyash root, 10-20 parts of sophora flavescens, 10-20 parts of senecio scandens, 10-20 parts of rhizoma kaempferiae, 10-20 parts of acorus calamus, 10-20 parts of folium artemisiae argyi, 10-20 parts of borneol, 10-20 parts of flos magnoliae, 10-20 parts of asarum, 10-20 parts of clove, 10-20 parts of saposhnicovia divaricata, 10-20 parts of cassia twig, 10-20 parts of cinnamon, 10-20 parts of rhizoma cyperi, 10-20 parts of bletilla striata, 10-20 parts of fortune eupatorium herb and 10-20 parts of geranium. The additive is prepared from multiple natural herb extracted ingredients, is natural and mild, can be used for preventing mosquito bite and quickly relieving discomfort after mosquito bite, is pure and mild, is non-irritative and can be used for bringing safe care to adult skins, and keeping people away from mosquito intrusion in summer. The fabric of underware containing the additive is natural, mild, safe, non-greasy, fitting and comfortable.

The invention relates to a gel solution for treating gastric ulcer and gastrorrhagia. The gel solution is characterized in that carboxymethylcellulose sodium and other gels are compounded to form a solution substrate; and the medicament is carried with honey and sesame oil. The gel solution has the advantages that: 1, the solution can form a layer of protective film on the surface of stomach and duodenum, isolates the functions of stimulation and erosion of gastric acid, protease and food on an ulcer part, thereby accelerating rehabilitation and healing of the ulcer face; and 2, the solution has the function of hemostasis and has obvious hemostatic effect on gastrorrhagia.

The invention discloses an antitumor slow-release implant having strong adhesion and hemostasis functions and a preparation method thereof. Inspired by mussel adhesion mechanism and catechol and iron ion chelating mechanism, postoperative thermal chemotherapy hydrogel based on mussel adhesion mechanism deriving is developed successfully through bionic design and serves as a multifunctional operative tissue adhesion and treatment agent. Main ingredients of the implant include chitosan, gallic acid, Fe3+ chelating agent and drug. Coating and treating of a wound can be performed by covalently crosslinking and freeze-drying chitosan and gallic acid, dissolving before use, adding antitumor drug, utilizing the Fe3+ chelating agent for crosslinking and ultrasonically mixing well to form gel. The implant has various functions of adhesion, hemostasis, bacteria resisting, inflammation diminishing and thermal chemotherapy of the wound, and postoperative relapse prevention of tumor can be realized by coating an irregular wound of the tumor with the implant and performing mild thermal chemotherapy.

The invention discloses an endoscopic minimally invasive hoe scaler, comprising a catheter, hemostatic forceps, an operating grip and an operation control device. The endoscopic minimally invasive hoe scaler is characterized in that a head of the catheter is connected with the hemostatic forceps while a tail of the catheter is matched connection with the operating grip; the hemostatic forceps are composed of a subwarhead-shaped hollow binding clip of which two halves are closed and opened correspondingly; the hoe scaler is a plasma hoe scaler formed by a steel wire structure, and extends into a linked tube of the hemostatic forceps; the operating grip is provided with a hemostatic forceps push ring and a hoe scaler control grip capable of moving back and forth; and the operation control device comprises a hemostatic forceps operation control device and a hoe scaler operation control device. The endoscopic minimally invasive hoe scaler solves the defects in the prior treatment on digestive tumor, and comprises both the hoe scaler and the hemostatic forceps, so that cockamamie operations of repeatedly changing a plurality of prior instruments in the world at present are avoided; and after being powered on, the endoscopic minimally invasive hoe scaler has the functions of the biopsy forceps and the hemostatic forceps, and the function of incision, so that the detection, the incision and the haemostasis in time can be convenient, and the complications of bleeding can be reduced.

The invention discloses bone regeneration guiding collagen membrane for dental use and a preparation method thereof, and belongs to the technical field of regenerative medical materials. The preparation method of the bone regeneration guiding collagen membrane for dental use comprises the following steps: S1, preparing a raw material and carrying out pretreatment, including: S1-1, dissolving type-I collagen in an acidic solvent and carrying out homogenization so as to obtain collagen slurry, S1-2, filtering the collagen slurry, and S1-3, performing negative-pressure pumping on the collagen slurry filtered in S1-2 until no obvious bubbles exist; S2, carrying out freeze-drying, namely freeze-drying the collagen slurry prepared in S1 so as to obtain collagen sponge; S3, pressing the collagensponge into a thin piece, namely pressing the collagen sponge into a thin piece under a pressure of 1-5 MPa; and S4, performing severe dehydration and cross-linking on the thin piece in vacuum so as to obtain the bone regeneration guiding collagen membrane for dental use, and carrying out sterilizing and storing. The bone regeneration guiding collagen membrane for dental use disclosed by the invention can be used to stop bleeding and guide bone regeneration after dental implantation, and has the advantages of being low in immunogenicity, excellent in biocompatibility and capable of effectivelypromoting bone regeneration. Moreover, the preparation method of the bone regeneration guiding collagen membrane for dental use has the advantages of being efficient and easy in operation, non-toxicand harmless.

The invention provides a preparation method of a composite carbon nano tube reinforced hydroxyapatite material and relates to a composition using phosphate as a basic material. A chemical vapor deposition method is used for preparing carbon nano tubes, functionalization treatment is conducted on the carbon nano tubes, a method integrating a magnetic liquid-phase stirring method and a hydrogel method is adopted to conduct in-site collagen layer coating on the surfaces of the carbon nano tubes subjected to the functionalization treatment, and thus the collagen coated composite carbon nano tube reinforced hydroxyapatite material is prepared through a dry-state press-forming method. The method overcomes the defects that the composite carbon nano tube reinforced hydroxyapatite material ubiquitous in the prior art is low in interface bonding strength and poor in carbon nano tube dispersity and accordingly the comprehensive mechanical property of the composite material is low; the composite material is poor in biocompatibility, or even has toxicity, and certain risk exists when the material serves as a biomedical material; the effect of repairing migration, growth and differentiation of bone cells is poor; the material is poor in usage effect when serving as the biomedical material.

Belonging to the field of medicines, the invention in particular relates to a Dendrobium officinale patch with a hemostatic function. The active ingredient of the patch is Dendrobium officinale fruit powder. Tests prove that the Dendrobium officinale patch provided by the invention has an obvious hemostatic effect on experimental animals. The Dendrobium officinale patch can be used for trauma hemostasis, and has the characteristics of obvious curative effect and convenient use.

The invention particularly relates to an injectable hydrogel dressing based on polyphenol-gallium ion coordination as well as a preparation method and application of the injectable hydrogel dressing. The hydrogel compound dressing is prepared from the following raw materials in percentage by mass: 3-30% of an antibacterial high-molecular compound, 3-30% of a natural polyphenol compound, 3-30% of an inorganic gallium compound and deionized water. The hydrogel auxiliary material has good injectable performance, antibacterial performance, hemostatic performance and antioxidant effect, and can significantly improve the wound healing effect in a mouse full-thickness skin wound simulation model.

The invention discloses a chitosan-based bleeding stopping paste as a bone wax substitute, and a preparation method thereof. The preparation method comprises: dissolving carboxymethyl chitosan with aviscosity average molecular weight of 100000-150000 and a substitution degree of 50-150% in distilled water, adding chitosan with a viscosity average molecular weight of 100000-300000 and a deacetylation degree of more than 85%, and calcium alginate, uniformly stirring, sealing, and sterilizing with ethylene oxide. According to the present invention, the chitosan-based bleeding stopping paste hasstrong plasticity, can block bone cross-sections or any tissue gaps, and further has the bleeding stopping function, wherein the bone wax does not have the bleeding stopping function; the chitosan-based bleeding stopping paste can rapidly stop the bleeding of venous hemorrhage and capillary hemorrhage models; and CM-CS, CS and Al are natural polymer derivatives, can be completely degraded, and have good antibacterial properties, such that the postoperative infection can be reduced, and the risk of chronic inflammation and other adverse reactions can be reduced.

The invention relates to an eliminating turmeric acne gel paste for treating acne, which is characterized in that sodium carboxymethyl cellulose and other gels are compounded into a paste matrix; and the paste carries with carbon powder which is obtained by burning and baking an eliminating acne turmeric extraction liquid and residue thereof. The gel paste has the following advantages that: 1, the paste has hemostasis function; 2, the paste has the function of inhibiting the growth of bacteria; 3, the paste can prolong the time of medicament release; 4, the paste generates the bioadhension so as to firmly adhere to an afflicted part; 5, the paste has adsorption function on a tissue fluid generated by the acne; 6, the paste has the functions of inhibiting the growth of fibrocyte and reducing scars; 7, the paste makes a preparation more stable; and 8, the paste is convenient to carry and use.

The invention relates to an eliminating acne turmeric gel film agent for treating acne, which is characterized in that sodium carboxymethyl cellulose and other gels are compounded into a paste matrix; and the paste carries with carbon powder which is obtained by burning and baking an eliminating acne turmeric extraction liquid and residue thereof. The gel film agent has the following advantages that: 1, the film agent has hemostasis function; 2, the film agent has the function of inhibiting the growth of bacteria; 3, the film agent can prolong the time of medicament release; 4, the film agent generates the bioadhension so as to firmly adhere to an afflicted part; 5, the film agent has adsorption function on a tissue fluid generated by the acne; 6, the film agent has the functions of inhibiting the growth of fibrocyte and reducing scars; 7, the film agent has good ventilation property; 8, the film agent makes a preparation more stable; and 9, the film agent is convenient to carry and use.

The invention discloses a long-acting recombinant III-type collagen expressed by saccharomyces cerevisiae and an application of the long-acting recombinant III-type collagen in cosmetics. The amino acid sequence of the long-acting recombinant III-type collagen comprises a basic repetitive unit and a terminal amino acid sequence. The basic repetitive unit comprises a human type III collagen peptide fragment, and the amino acid sequence of the human type III collagen peptide fragment is GERGAPGFRGPAGPNGIPGEKGPAGERGAP. The terminal amino acid sequence comprises a human type II collagen peptide fragment, and the amino acid sequence of the human type II collagen peptide fragment is GPPGPCCGGG. The long-acting recombinant III-type collagen provided by the invention has good biocompatibility and good cell adhesion, can promote formation of new cells, has a hemostatic function, and has a stronger function of promoting growth of epithelial cells. Compared with collagen extracted from animal tissues and foreign bodies, the long-acting recombinant III-type collagen has the advantages of solubility, no virus hidden danger and low rejection reaction.

The invention relates to a common bletilla tuber health-care scented tea product. The common bletilla tuber health-care scented tea product consists of the following raw material components in parts by weight: 20-35 parts of common bletilla tubers, 10-20 parts of ampelopsis grossedentata, 3-15 parts of figs, 3-10 parts of licorice roots, 5-10 parts of orange peel, 5-10 parts of Chinese wolfberry fruits, and 5-10 parts of a common bletilla tuber extract. The common bletilla tubers are extracted to obtain the common bletilla tuber extract, and the common bletilla tuber extract is directly addedto the tea product, so that the purpose of sufficient use of the common bletilla tuber raw materials is realized, the utilization rate of the common bletilla tuber scented tea is effectively increased, and the tea soup obtained by brewing the tea product without the common bletilla tubers is consistent in color with that obtained by brewing the tea product with the common bletilla tubers; functional components of the common bletilla tubers capable of stopping bleeding and the like are used, so that the common bletilla tuber scented tea product not only has rich composite fragrance, but also has the function of stopping bleeding; fermentation and baking are performed on orange peel and Chinese wolfberry fruits, so that the special fragrance of the orange peel is effectively reduced, the content of volatile oil is effectively reduced, and the dissolving out speed of polysaccharide in the Chinese wolfberry fruits can also be increased.