46results about How to "Good hemostatic ability" patented technology

The invention relates to an alginate antibacterial dressing and its preparation method. The preparation method comprises the following steps of: preparing a spinning stock solution from soluble alginate, a water-soluble chitosan derivative or water-soluble chitin derivative and simultaneously adding a silver-based antibacterial agent into a coagulation bath, carrying out wet spinning to obtain a blend fiber product and further obtain the alginate antibacterial dressing, which can be used as a wound dressing, a hemostatic material and the like. The antibacterial dressing obtained in the invention has good biocompatibility, permeability and water absorption, can be used to rapidly stop bleeding, ease pain and promote wound healing, continuously acts on regenerative bacteria, and has a lasting and high-efficient sterilizing characteristic.

A staltic soluble cellulose sponge is proportionally prepared from carboxymethyl cellulose sodium and chitosan through dissolving carboxymethyl cellulose sodium in distilled water, dissolving chitosan in diluted acetic acid, mixing, adding polyethanediol 400, cane sugar and glycerin, stirring, laying aside while defoaming, filming, and vacuum freeze-drying.

An ultrahigh-absorption styptic dressing made of calcium alginate is prepared through mixing carboxymethyl chitosan with calcium alginate fibres, preparing non-woven cloth, attaching it on the one surfaces of acetate fibre cloth, and attaching an impervious layer on its another surface.

The invention discloses an alkylated chitosan multifunctional hydrogel as well as a preparation method and application thereof. The preparation method of the alkylated chitosan multifunctional hydrogel comprises the following steps: (1) preparing alkylated chitosan; (2) preparing an alkylated chitosan solution, and preparing a four-arm polyethylene glycol benzaldehyde solution; and (3) mixing thealkylated chitosan solution and the four-arm polyethylene glycol benzaldehyde solution, and performing gelatinization at room temperature. According to the method provided by the invention, an alkanechain is used to modify an amino group of chitosan to prepare the alkylated chitosan, the hydrophobic alkane chain and a hydrophobic cell membrane can be fixed to each other by hydrophobic interaction, so that blood cells can be fixed on the long chain of the chitosan, blood is coagulated, and bleeding is quickly stopped; and polyethylene glycol benzaldehyde is cross-linked through an imine bond to form the stronger-functional more-stable self-repairing hydrogel, and the hydrogel has the functions of concentrating the blood to stop bleeding, absorbing exudate, and promoting wound repair of a hydrogel.

The invention provides a water-soluble hemostatic material and a preparation method thereof, relating to a hemostatic material and a preparation method thereof. The invention solves the defects that the existing chitosan hemostatic material has poor hemostatic performance and can not deal with a larger amount of bleeding. The water-soluble hemostatic material is prepared from oxidized regenerated cellulose, chitosan solution and alkaline alcoholic solution. The preparation method comprises the following steps of: (1) soaking the oxidized regenerated cellulose into the chitosan solution, then carrying out suction filtration for washing with deionized water, and removing the moisture on the surface of the oxidized regenerated fiber loaded with chitosan; (2) putting the oxidized regenerated fiber loaded with chitosan into the alkaline alcoholic solution to be sealed to carry out a neutralization reaction; and (3) flushing with ethanol solution, then flushing with anhydrous ethanol, and drying to obtain the water-soluble hemostatic material. The water-soluble hemostatic material provided by the invention can be used as a hemostatic material.

The invention provides a gelatin composition. The gelatin composition comprises hydroxylated gelatin, microbial glutamine transaminase and protein glutaminase, wherein the hydroxylated gelatin is 20-60%proline-hydroxylated gelatin. The gelatin composition has an extremely-good bleeding stopping effect at a temperature in a range of 4-10DEG C. The invention also discloses a preparation method of the gelatin composition and an application of the gelatin composition.

The invention discloses a preparation method of an asymmetric composite sponge. The method comprises preparing sodium carboxymethyl cellulose into a solution with a concentration of 1% with distilled water, and preparing chitosan with dilute acetic acid into a solution with a concentration of 1%. The gelatin is made into a solution with a concentration of 1% with warm water; sodium carboxymethyl cellulose, gelatin and chitosan are measured according to the ratio of 1:0.5~3:0.5~3 by volume, left standing for defoaming, poured into In the membrane device, the sponge product is obtained by vacuum freeze-drying; put the sponge product into a watch glass of carbodiimide solution, seal it with a plastic wrap, place it on a decolorizing shaker, vibrate for 24 hours, add distilled water, and seal the mouth with a plastic wrap , placed on a shaker, shaken for 1 h, and repeated this operation three times. The cross-linked sponge is pre-frozen twice and dried to obtain an asymmetric composite sponge. The product prepared by the invention has strong hemostatic effect, is convenient for clinical use, and has good water absorption and water retention properties and drug loading performance.

The invention discloses an ultrasonic scalpel with enhanced hemostatic ability. The ultrasonic scalpel with enhanced hemostatic ability sequentially comprises, from near to far, a longitudinal-torsional compound vibration ultrasound transducer, an ultrasonic horn and an ultrasonic blade; and the ultrasonic scalpel further comprises an instrument box arranged with a transmission system in the bottom case. The longitudinal-torsional compound vibration ultrasound transducer comprises plural pieces of thickly polarized piezoelectric ceramics located between a front end cap and a middle end cap, and plural pieces of tangentially polarized piezoelectric ceramics located between the middle end cap and a rear end cap; the thickly polarized piezoelectric ceramics are used for generating longitudinal vibration; and the tangentially polarized piezoelectric ceramics are used for generating torsional vibration. The ultrasonic scalpel with enhanced hemostatic ability has the advantage of being capable of yielding faster hemostatic results due to adoption of torsional vibration perpendicular to tissue surface generated by a torsional vibration mode during coagulation of a blood vessel; and thus,the ultrasonic scalpel can be used for coagulating thicker blood vessels. Moreover, the ultrasonic scalpel with enhanced hemostatic ability can very well coagulating blood vessels with traction tension so as to reduce operation risk and difficulty of doctors' operation; and the ultrasonic scalpel can be used in surgical robot systems.

The invention relates to injectable and degradable dry hemostatic cryogel with good shape memory and blood coagulation capability as well as a preparation method and an application of the injectable and degradable dry hemostatic cryogel. Chitosan is resuspended in deionized water, glacial acetic acid is dropwise added under stirring, and a CS solution is obtained after uniform mixing; dopamine hydrochloride is added to the deionized water to prepare a DA solution; the CS solution is mixed with the DA solution, an oxidant solution is added simultaneously, and the solutions are uniformly mixed to obtain a mixed solution; and finally, the mixed solution is placed at the temperature of subzero 7-subzero 20 DEG C to react for 12-36 h, a cross-linked cryogel network in a frozen state is obtained, and is placed in the deionized water to be melted, freeze drying is conducted, and the injectable and degradable dry hemostatic cryogel with good shape memory and blood coagulation capability is obtained. The cryogel dressing has high elasticity and ultrafast shape recovery capability, can quickly absorb blood, and has photo-thermal antibacterial performance and the like.

The invention discloses a traditional Chinese medicine preparation for treating the Chinese soft-shell turtle rotten-skin disease caused by edwardsiella and a preparing method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is medicine powder prepared from, by weight, 15-25% of isatis root, 5-15% of rheum officinale, 5-15% of sophora flavescens, 5-15% of humifuse euphorbia herb, 5-15% of Chinese gall, 5-13% of liquorice, 5-13% of folium isatidis, 5-15% of amur cork tree bark, 5-13% of houttuynia cordata and 3-9% of fructus forsythiae. The sum of the percentages of all the components is 100%. The traditional Chinese medicine preparation for treating the Chinese soft-shell turtle rotten-skin disease caused by the edwardsiella has the advantages of being good in treating effect on treating the Chinese soft-shell turtle rotten-skin disease caused by the edwardsiella and free of drug residues.

The invention discloses a phyllanthus emblica leaf extractive preparation method which comprises the following steps: (1) soaking; (2) pulping and performing enzymolysis; (3) performing carbon dioxidesupercritical extraction; (4) separating; (5) distilling and freeze drying to obtain the phyllanthus emblica leaf extractive. According to the preparation method disclosed by the invention, are soaked and activating treatment is performed at first and then the activated phyllanthus emblica leaves are subjected to crush and pulp, and enzymolysis treatment is performed; thus, cell walls of the phyllanthus emblica leaves are damaged, the phyllanthus emblica particles are refined, effective ingredients in the phyllanthus emblica leaves can be extracted out more easily, quality is improved, and extracting time is shortened; then the carbon dioxide supercritical extracting method is utilized to extract the active ingredients of the phyllanthus emblica leaves, the purity is high, damage to the active ingredients is effectively reduced, and quality of a finished product is ensured. The phyllanthus emblica leaf extractive prepared by the preparation method disclosed by the invention can be added into pharmaceutical adjuvant to be prepared into corresponding preparation, can be applied to treating or assisting to treat aids, can strengthen patient physique and can improve patient life quality.

The invention provides a medical developing dressing as well as a preparation method and production equipment thereof, and relates to the technical field of preparation of medical gel dressings. The medical developing dressing comprises a non-woven gauze and an absorbent gauze which are compounded; at least two developing lines which are parallel to each other and are uniformly arranged are arranged on one side, away from the absorbent gauze, of the non-woven gauze; the outer surface layer of the non-woven gauze is provided with an antibacterial layer and a liquid absorption layer which wrap the non-woven gauze, the antibacterial layer is located between the non-woven gauze and the liquid absorption layer, and the developing lines are located between the antibacterial layer and the non-woven gauze; a plurality of containing grooves located between the adjacent developing lines are evenly formed in the non-woven gauze; and openings of the containing grooves are located in the side, close to the absorbent gauze, of the non-woven gauze and protrude towards the side, away from the absorbent gauze, of the non-woven gauze, and the containing grooves are filled with hemostatic. The developing dressing prepared by the invention has relatively strong imbibition capacity and hemostasis capacity, the use effect is effectively improved, the developing dressing can be tracked by a medical image, the developing lines are not easy to fall off, and medical negligence caused by the fact that the medical developing dressing is left in the body of a patient is avoided.

The invention belongs to the technical field of medical products, relates to a material for stopping bleeding and in particular relates to bionic cloth for stopping bleeding. The bionic cloth for stopping bleeding has a multilayered structure and comprises a repairing dissolving layer, an isolation and ventilation layer, a bleeding stopping medicine layer and a covering outer layer in sequence, wherein the repairing dissolving layer is cyanoacrylate tissue glue; the isolation and ventilation layer is formed by weaving cotton and hemp fibers; the bleeding stopping medicine layer is a medical treatment medicament; the covering outer layer is cotton and hemp fiber cloth; the repairing dissolving layer, the isolation and ventilation layer, the bleeding stopping medicine layer and the coveringouter layer are stuck and cured together through crosslinking; the bleeding stopping medicine layer is prepared from the following components in percentage by mass: 22 to 24 percent of mannitol, 0.5 to 12.6 percent of chitosan, 9 to 22 percent of vitamin C, 5.2 to 6.5 percent of dexamethasone, 2.0 to 2.2 percent of thrombin, 2.0 to 3.2 percent of polyvinyl alcohol, 0.2 to 0.5 percent of sodium dodecyl sulfonate, 0.5 to 7.2 percent of modified zeolite and the balance of starch micro-pore polysaccharide granules. After the product absorbs a lot of blood, the volume is expanded so that blood vessel ruptures or wounds are sealed and a barrier is provided for a bleeding stopping opening; the bionic cloth has a more rapid healing speed and a better effect.

The purpose of the present invention is to provide a lipid-containing hemostatic material capable of promoting adhesion or agglutination of platelets even without having a protein or a peptide supported thereon, such as GPIb and H12, involved in for adhesion or agglutination of platelets. In order to accomplish said purpose, provided is a hemostatic material (10) provided with a water-insoluble base material (1) and a lipid supported on the surface of the base material (1), wherein the lipid comprises one or more types of anionic lipid.

The invention discloses a positively charged bio-fiber hemostatic and antibacterial material as well as a preparation method and an application thereof. The material is a non-woven fabric material, aknitted fabric material, a woven fabric material, a machine knitting fabric material, a gauze material, a fiber strip material, a fiber cotton ball material or a fiber flocculent material which is formed by biological fibers containing biological polysaccharide quaternary ammonium salt. The positively charged bio-fiber hemostatic and antibacterial material is applied to preparation of medical materials and functional dressings for rapid hemostasis, sterilization, bacteriostasis and wound healing promotion. The material has the advantages that firstly, the biological polysaccharide quaternary ammonium salt with positive charges has stronger positive charges than primary amino; secondly, the material has a loose fiber structure; and therefore, the material has excellent hemostasis performance and sterilization and bacteriostasis performance, and also has the effect of promoting wound healing. The material is convenient to use and operate clinically, can be used for covering, filling andbinding surgical wounds and traumatic wounds very conveniently, can play the functions of stopping bleeding, inhibiting bacteria and promoting healing at the same time, and can better meet clinical application.

The embodiment of the invention discloses a fusion wave laser output device and a laser therapy apparatus. The fused wave laser output device comprises a first laser, the first laser comprises a first controlled end and a continuous laser output end, and the first laser is used for outputting continuous laser through the continuous laser output end according to a first control signal received by the first controlled end; a second laser comprises a second controlled end and a pulse laser output end, and the second laser is used for outputting pulse laser through the pulse laser output end according to a second control signal received by the second controlled end; a controller is used for simultaneously sending the first control signal and the second control signal; an output fiber; and a beam combiner is used for coupling the continuous laser and the pulse laser into the output optical fiber. According to the embodiment, the operation efficiency can be improved, the visual field condition in the operation is improved, the postoperative recovery speed of a patient is increased, and the blood loss amount in the operation is reduced.

The invention belongs to the technical field of preparation of gels to treat bone and joint pain and relates to a Chinese-hemp-derived composition and gel to treat rheumatic bone and joint pain and apreparation method of the gel. The gel herein is mainly made from twotooth achyranthes root extract, ginger extract, astragalus root extract, Angelica sinensis extract, mulberry leaf extract, Chinesehemp leaf extract, Chinese hemp stalk-based activated carbon, sodium hyaluronate, sodium carboxymethylcellulose, glycerol, and purified water. The Chinese hemp stalk-based activated carbon has rich duct structure and surface functional groups on the surface, has good chemical stability, and can increase absorption rate and absorption depth for infrared radiation therapy and increase the absorptionrate of local exudation. Good treatment effect is attained through scientific compatibility; under assistance of an infrared radiation apparatus, the effect rate for rheumatic joint pain reaches 100%.