Styptic powder

Abstract

The invention aims to provide a crosslinking poly glutamic acid calcium microsphere. The adopted base material poly glutamic acid is a polyamino acid material obtained through microorganism fermentation synthesis, controllable in structure, biodegradable, excellent in biocompatibility, simple in product forming technology and easy to control in quality; in addition, the hemostasis process of the crosslinking poly glutamic acid calcium microsphere is not affected by normal clotting mechanism and can still play the stypticity for patients using an anticoagulant and with low blood platelets and complete blood cells; release of Ca <2+> in the material can accelerate activation of intrinsic coagulation factors to realize the auxiliary stypticity; moreover, poly glutamic acid has better biological adhesiveness, facilitates control of continuous errhysis of tissues, and is higher in hemostasis capacity.

Description

technical field

[0001] The invention belongs to the technical field of biomedical materials, and in particular relates to a hemostatic powder. Background technique

[0002] In many cases, injury or uncontrolled bleeding after surgery is the leading cause of death. In various surgical operations, absorbable hemostatic materials can directly reduce blood loss in the body to effectively maintain blood volume, avoid adverse reactions caused by the use of systemic coagulation drugs, reduce blood transfusion and operation time; reduce postoperative exudation and complications Therefore, it has been highly valued by the medical and industrial circles of various countries. Common hemostatic materials come in a variety of dosage forms, including sponges, films, micropowders, gels, etc. The fields of application of different dosage forms of hemostatic materials are also different.

[0003] Absorbable hemostatic powder is a new type of hemostatic material developed in recent years. I...

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