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Medicine for treating acute/chronic colitis and preparation process thereof

A colitis, acute and chronic technology, applied in the field of preparation of the drug, can solve the problems such as the length of the disease course and the degree of the disease are not well balanced, the authenticity of the clinical conclusion is questioned, and the basic experimental research is few, etc., so as to inhibit the acute experimental ulcer. Colitis, reducing capillary permeability, promoting healing and recovery

Active Publication Date: 2006-02-22
昆明市医学科学研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still many problems to be solved: there is no unified cognition standard for TCM syndrome differentiation and classification, resulting in relative dispersion of the classification, duplication of syndrome manifestations among the classifications, so the prescriptions are messy, which is not conducive to academic exchanges, and the selection and observation of cases are difficult. The principles of randomization, control, and double-blindness were not implemented, the duration of the disease and the severity of the disease were not well balanced, and the observation data lacked strict statistical analysis, which led to doubts about the authenticity of the clinical conclusions. There are many clinical summaries and few basic experimental studies, especially few pharmacological studies on drugs with significant clinical efficacy. The disease has a long course of disease, good short-term effect of treatment, poor long-term effect, and often relapses. Therefore, anti-relapse is the key A big problem, this is the direction of future efforts

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] 1. Select the following raw materials (weight unit: kilogram):

[0037] Fupian 55, Coix Seed 25, Patrinia 12, Evodia 5, Coptis 8, Dried Ginger 12, Chishizhi 12, Chuanxiong 8, Cyperus cyperus 8, Swertia 12, Hedyotis diffusa 18.

[0038] 2. Prepare according to the following steps:

[0039] 1) washing the crude drug for subsequent use;

[0040] 2) Boil the attached slices in water for about 2 hours, and set aside;

[0041] 3) Add the remaining ten herbs and decoct twice, the first time for 1 hour, the second time for 30 minutes, filter, combine the two filtrates, concentrate under reduced pressure to a thick paste, and dry in an oven (60°C) , get dry extract for later use;

[0042] 4) After pulverizing the dry extract, add an appropriate amount of excipient starch, perform wet granulation with 85% alcohol, and dry to obtain granules. Packing: 10g / bag, each bag is equivalent to 51.25g of crude drug, this product is dark brown granules, bitter in taste.

Embodiment 2

[0044] 1. Select the following raw materials (weight unit: kilogram):

[0045] Fupian 60, Coix seed 30, Patrinia 15, Evodia 6, Coptis 9, Dried ginger 15, Chishizhi 15, Chuanxiong 10, Cyperus 10, Swert sprout 15, Hedyotis diffusa 20.

[0046] 2. Prepared according to the method of Example 1.

Embodiment 3

[0048] 1. Select the following raw materials (weight unit: kilogram):

[0049] Fupian 65, Coix Seed 35, Patrinia 17, Evodia 8, Coptis 10, Dried Ginger 17, Chishizhi 17, Chuanxiong 12, Cyperus 12, Swert sprout 17, Hedyotis diffusa 25.

[0050] 2. Prepared according to the method of Example 1.

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PUM

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Abstract

The invention relates to a medicine for treating acute / chronic colitis and preparation process, wherein the medicine is prepared from the following traditional Chinese medicinal herbs (by weight portion), slice of aconite 55-65, coix seed 25-35, herba patriniae 12-17, evodia rutaecarpa 5-8, coptis root 8-10, dried ginger 12-17, red halloysite 12-17, Ligusticum wallichii 8-12, nutgrass flatsedge rhizome 8-12, swertiamar 12-17, and oldenlandia 18-25.

Description

technical field [0001] The invention relates to a medicine for treating acute and chronic colitis, specifically a Chinese patent medicine prepared from Chinese herbal medicines as raw materials, and also relates to a preparation method of the medicine. Background technique [0002] In recent years, with the improvement of people's living standards and changes in diet structure and lifestyle, the incidence of acute and chronic colitis in our country has been increasing year by year, and has been widely valued by the medical circles at home and abroad. Western medicine treatment mainly contains sulfasalazine, aminosalicylic acid, corticosteroids, immunosuppressants, etc., but due to the unstable curative effect of these drugs and the large side effects of drugs, people have tried to treat this disease by combining traditional Chinese and Western medicine in recent years, and achieved good results. curative effect. Ulcers are difficult to heal due to lingering conditions and e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/16A61P1/00
Inventor 吴荣祖
Owner 昆明市医学科学研究所