Application of wogonin for preparing medicine to treat or prevent hepatitis B

A technology of wogonin and medicine, which is applied in the field of application of wogonin in the preparation of drugs for treating or preventing hepatitis B, can solve the problems of not specifying the specific type of hepatitis, and not disclosing the pharmacological effect of wogonin on hepatitis, and achieve good curative effect , small side effects, and the effect of inhibiting replication

Active Publication Date: 2006-06-14
CHINA PHARM UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this document does not disclose the pharmacological effect of wogonin on hepatitis, and does not point out the specific type of hepatitis that can be treated. The present invention has carried out further research on this basis

Method used

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  • Application of wogonin for preparing medicine to treat or prevent hepatitis B
  • Application of wogonin for preparing medicine to treat or prevent hepatitis B
  • Application of wogonin for preparing medicine to treat or prevent hepatitis B

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] Take 10g of wogonin, add appropriate auxiliary materials for injections (including freeze-dried powder injections and sterile subpackaged dry powder injections), and prepare anti-hepatitis B drug injections according to the injection (including freeze-dried powder injections and sterile subpackaged dry powder injections) process.

Embodiment 2

[0098] Take wogonin 10g, add suitable auxiliary materials for tablets (including sustained and controlled release tablets, matrix tablets, coated tablets, dispersible tablets, etc.), press the tablet (including sustained and controlled release tablets, matrix tablets, coated tablets, dispersible tablets, etc.) ) technology is prepared into anti-hepatitis B tablet.

Embodiment 3

[0100] Get 10g of wogonin, add appropriate auxiliary materials for capsules, and prepare anti-hepatitis B drug capsules according to the capsule process.

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PUM

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Abstract

An application of wogonin in preparing the medicines for preventing and treating hepatitis B by suppressing the copying of HBV DNA and the secretion of s and e antigens of hepatitis B and decreasing the content of HbsAg in serum is disclosed.

Description

technical field [0001] The invention belongs to the field of pharmacy and relates to the application of wogonin in the preparation of medicines for treating or preventing hepatitis B. Background technique [0002] Viral hepatitis B (hepatitis B) is an infectious disease caused by hepatitis B virus (HBV), which is mainly caused by liver inflammatory lesions and can cause multiple organ damage. , mainly affects children and young adults, and a small number of patients can be transformed into liver cirrhosis or liver cancer. Hepatitis B has become a worldwide disease that seriously threatens human health. It is also the most widespread and most harmful infectious disease in China. According to reports, about 120 million people in my country are carrying hepatitis B virus, of which more than 30 million are chronic hepatitis B patients. 350,000 people die from chronic hepatitis B-related diseases every year. Research and development of drugs for the treatment and prevention of h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P1/16A61P31/20
Inventor 尤启冬齐琦王伟郭青龙张坤赵丽顾红燕张海伟胡扬
Owner CHINA PHARM UNIV
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