False portulaca oleracea extracts, its prepn. and usage

A technology of bacopa monniera and its extract, which is applied in the field of bacopa monniera extract, can solve the problems of unfavorable large-scale industrial production operation and high cost, and achieve the effect of remarkable drug effect, low cost and large processing capacity

Inactive Publication Date: 2010-08-11
CHENGDU WAGOTT PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

) This extraction process is separated and refined with acetone, using organic solvents such as acetone that are harmful to the human body, which is unfavorable for large-scale industrial production operations and high cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 Bacopa monniera extract of the present invention

[0028] 200g dried whole plant of Bacopa monnieri, reflux extraction with 40% ethanol three times, the dosage is 10, 8, 6 times respectively, each extraction for 1 hour, the three extractions are filtered and concentrated until alcohol-free, adsorbed by macroporous adsorption resin, Wash with water until colorless, first elute with 10% ethanol, then elute with 95% ethanol, concentrate the eluate with 95% ethanol, and dry to obtain 3.4 g of product with aglycone content of 21.8%.

Embodiment 2

[0029] The preparation of embodiment 2 Bacopa monniera extract of the present invention

[0030] 60kg whole herb raw material, reflux extraction with 70% ethanol twice, the dosage is 10, 10 times respectively, each extraction for 1 hour, filter and combine the filtrate, concentrate the filtrate on the column, wash with water until colorless, wash with 120L of 95% ethanol The eluate was spray-dried to obtain 200 g of product, the glycoside content: 31.1%.

Embodiment 3

[0031] The preparation of embodiment 3 Bacopa monniera extract of the present invention

[0032] 350g dried whole plant of Bacopa monnieri, reflux extraction with 80% ethanol three times, dosages are: 8, 8, 6 times respectively, 1.5 hours for each extraction, filter and concentrate the three extracts to 600ml, absorb with macroporous adsorption resin, first Wash with water until colorless, then elute with 600ml of 10% ethanol, and then with 1000ml of 95% ethanol. Concentrate and dry the 95% ethanol eluate to obtain 6 g of dry powder. The glycoside content is 43.24%.

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Abstract

An extract of pseudo-portulaca, which contains the pseudo-portulaca saponin (20-80 Wt %), is disclosed. A composite medicine containing said extract, its preparing process and its application are disclosed.

Description

technical field [0001] The invention relates to an extract of Bacopa monniera, specifically, an extract made of natural medicinal material Bacopa monniera as a raw material, including a preparation method and application of the extract, and belongs to the field of medicine. Background technique [0002] Bacopa monniera is the whole herb of Bacopa monninera in the family Scrophulariaceae, and it is a traditional herbal medicine in India. It has the effects of clearing heat and detoxification, reducing inflammation and reducing swelling, and can treat red eye dysentery, red eyes, swelling and pain, red and swollen skin, etc. It is a famous medicine in India for calming the nerves and improving memory. [0003] At present, the report about Bacopa monniera has: Yang Xiaofeng, Song Chunqing, artificial product in natural product research, Acta Pharmaceutica Sinica, 1999,34 (12) discloses " the alcohol extract of Indian herbal medicine Bacopa monnieri can obviously improve Cognit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P25/00A61K36/80A61P25/24
CPCA61K36/80A61K31/7048A61P25/00A61P25/24A61P25/28
Inventor 阳明富黄云秀雷玉萍
Owner CHENGDU WAGOTT PHARMA
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