Radix aconiti agrestis extract and its preparing method

A technology of extract and Radix Root, applied in the field of Radix Root Extract, can solve the problems of adding water, decocting times, difficult firepower, improperly compatible prescriptions, inconvenient for large-scale production operation and quality control, etc., and achieves economical processing. cost, the effect of expanding drug sources

Inactive Publication Date: 2010-07-28
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In general self-prepared medicinal wine, the source of the drug is complicated, the dosage is large, and the compatible prescription is improper; the concentration of the wine is high, up to 35%-45%; the brewing time is long, the concentration is high; the taking time is long, or Taking it in an emergency can easily lead to poisoning, and aconitine is unstable in alcohol. As for whether it is related to toxicity, further research is needed
When used by patients, the Pharmacopoeia stipulates that it should be decocted first and used for a long time. As for how long it should be decocted first, it is difficult to control the amount of water, the number of decoctions, and the firepower in practice, which is not convenient for large-scale production operations and quality control.

Method used

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  • Radix aconiti agrestis extract and its preparing method
  • Radix aconiti agrestis extract and its preparing method
  • Radix aconiti agrestis extract and its preparing method

Examples

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Effect test

Embodiment 1

[0028] The preparation of embodiment 1 raw grass black water extract

[0029] Take 13.50 kg of raw Aconitum aconitum, soak in water for 30 minutes, add 10 times the amount of water to decoct, the decoction time is 3 hours after boiling, add 10 times the amount of water for the second time, decoct for 3 hours, filter, and combine the filtrate , concentrated under reduced pressure to 1.02-1.05 (60°C), dried to obtain 2.45Kg of extract, the inlet air temperature: 90-100°C, and the outlet air temperature: 60-65°C.

Embodiment 2

[0030] Embodiment 2 Preparation of Aconiti officinalis water extract

[0031] Take 12.50 kg of Aconitum aconitum medicinal material, soak in water for 30 minutes, add 10 times the amount of water to decoct, the decoction time is 3 hours after boiling, add 10 times the amount of water for the second time, decoct for 3 hours, filter, and combine the filtrate , concentrated under reduced pressure to 1.02-1.05 (60°C), dried to obtain 2.21Kg of extract, the inlet air temperature: 90-100°C, and the outlet air temperature: 60-65°C.

Embodiment 3

[0032] The preparation of embodiment 3 raw grass black water extract granules

[0033] Take 13.00kg of raw Aconitum aconitum, soak in water for 30 minutes, add 9 times the amount of water to decoct, the decoction time is 2.5 hours after boiling, add 7 times the amount of water for the second time, decoct for 2.5 hours, filter, and combine The filtrate is concentrated under reduced pressure to 1.02-1.05 (60°C), dried to obtain 2.25Kg of extract, the air inlet temperature is 90-100°C, the outlet air temperature is 60-65°C, and the extract is added to starch granules, The whole grain is made into granules.

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Abstract

The present invention relates to a radix aconite kusnezoffii extract which is obtained by using radix aconite kusnezoffii or its prepared product as raw material through a certain preparation process. In every gram of said extract the aconitene C34H47NO11 content is 0.01mg-0.7mg and total alkaloid content is 0.90-2.40mg.

Description

technical field [0001] The invention relates to an extract of Aconiti officinale, which belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Aconitum kusnezoffii Reichb. is the dry tuberous root of Aconitum kusnezoffii Reichb. Excavate in autumn when the stems and leaves wither, remove fibrous roots and sediment, and dry. In the 2005 edition of the Chinese Pharmacopoeia, it is stipulated that it is highly toxic, and it is generally used after processing. Because of its good expelling wind and dampness, warming meridian and relieving pain. It is used in folk and preparations to treat anemofrigid-damp arthralgia, joint pain, cold pain in trusted subordinates, and pain caused by cold cancer. At present, there are more and more cases caused by rheumatism, and at the same time, the ability to live and work is lost. The toxic and side effects of modern medicine are relatively large, and the curative effect is not optimistic. [0003]...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61P29/00A61P19/02A61K125/00
Inventor 彭成郭力
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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